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排序方式: 共有10000条查询结果,搜索用时 15 毫秒
891.
892.
HLA-restricted T-cell recognition of Epstein-Barr virus-infected B cells 总被引:23,自引:0,他引:23
In mice the cytotoxic T-cell response to several types of virus is influenced by genes within the major histocompatibility complex; in particular, genetic control is exercised at the effector cell level through a requirement that virus-specific cytotoxic T cells recognise viral antigens in association with H-2K and H=2D region gene products on the surface of infected cells. In man the restriction which the analogous HLA-A, -B and -C-region gene products might place on virus-specific T-cell function is still in dispute. The earliest and most controversial evidence concerns the Epstein-Barr virus (EBV), a B lymphotropic agent which causes infectious mononucleosis (IM) and which induces an unusually vigorous T-cell response; cytotoxic T cells from IM patients' blood were shown to be EBV-specific yet, in contrast to mouse systems, apparently free of any obvious HLA restriction. Since then T-cell recognition of EBV-infected B cells has assumed particular significance as a model system for the study of cytotoxic T-cell function in man. This report describes the results of a new approach clearly indicating that HLA-A and -B region products do indeed have a role in this system. 相似文献
893.
H. E. Gray S. E. Wenzel W. G. Luttge S. F. Zornetzer 《Cellular and molecular life sciences : CMLS》1979,35(8):1126-1127
Summary An apparently transient elevation of basal morning (08.00 h) plasma corticosterone levels in male mice was found 48 h after bilateral electrolytic lesions of the brainstem locus coeruleus complex but was not observed 6 weeks after lesioning.Supported by Alfred P. Sloan Foundation research fellowships awarded to W.G. Luttge and S.F. Zornetzer. 相似文献
894.
Riassunto Vengono riportati i dati relativi allo sviluppo in funzione dell'età, della reatività immunologica primaria nel topo con nanismo ereditario preipofisario e nel corrispondente fratello normale. Mentre in quest'ultimo si è notato un graduale incremento della reattività immunitaria di tipo primario soprattutto a partire dalla fine del periodo di allattamento, nel topo nano la reattività immunitaria primaria è rimasta costante nel tempo su bassi livelli anche dopo lo svezzamento. Alla luce dei dati sperimentali riportati viene ipotizzata l'esistenza di un controllo ipofisario della reattività immunitaria primaria. 相似文献
895.
E. A. Savino M. F. Gimeno A. L. Gimeno 《Cellular and molecular life sciences : CMLS》1967,23(2):144-145
Zusammenfassung Oxamat, das die Lactat-Dehydrogenase hemmt, erniedrigt die Kontraktionsfähigkeit des Vorhofs mit und ohne Anwesenheit von Glucose im Medium und bei Hinzufügung von 2-DG oder Atropin. Hohe Konzentration von Pyruvat erhöht die Depression von Oxamat auf den Vorhof im Glucose-Milieu. Oxamat sensibilisiert das Gewebe für funktionellen Abbau durch Glycolyse.
This research was supported by grants No. 1441 and No. HE-994801 from Consejo Nacional de Investigaciones de la República Argentina, and from the National Institute of Health, respectively.
Research Fellow from the Consejo Nacional de Investigaciones de la República Argentina.
Established Investigator from the Consejo Nacional de Investigaciones de la República Argentina. 相似文献
This research was supported by grants No. 1441 and No. HE-994801 from Consejo Nacional de Investigaciones de la República Argentina, and from the National Institute of Health, respectively.
Research Fellow from the Consejo Nacional de Investigaciones de la República Argentina.
Established Investigator from the Consejo Nacional de Investigaciones de la República Argentina. 相似文献
896.
Riassunto Il dodecilsolfato di sodio causa la dissociazione dell'urease (massa molecolare 480,000) in una maniera che dipende fortemente sulla concentrazione relativa dei reagenti. Il prodotto ottenuto con un sufficiente eccesso di detergente ha una massa molecolare di 50,000–60,000.
This work was supported by Grant No. 11,573 and Career Award No. 5K3 GM 13,489 (to G.G.) from the National Institutes of Health, Department of Health, Education and Welfare. 相似文献
This work was supported by Grant No. 11,573 and Career Award No. 5K3 GM 13,489 (to G.G.) from the National Institutes of Health, Department of Health, Education and Welfare. 相似文献
897.
898.
899.
Pisolkar VG 《Nature》1970,225(5236):936-937
900.