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Blain S Quéguiner B Armand L Belviso S Bombled B Bopp L Bowie A Brunet C Brussaard C Carlotti F Christaki U Corbière A Durand I Ebersbach F Fuda JL Garcia N Gerringa L Griffiths B Guigue C Guillerm C Jacquet S Jeandel C Laan P Lefèvre D Lo Monaco C Malits A Mosseri J Obernosterer I Park YH Picheral M Pondaven P Remenyi T Sandroni V Sarthou G Savoye N Scouarnec L Souhaut M Thuiller D Timmermans K Trull T Uitz J van Beek P Veldhuis M Vincent D Viollier E Vong L Wagener T 《Nature》2007,446(7139):1070-1074
The availability of iron limits primary productivity and the associated uptake of carbon over large areas of the ocean. Iron thus plays an important role in the carbon cycle, and changes in its supply to the surface ocean may have had a significant effect on atmospheric carbon dioxide concentrations over glacial-interglacial cycles. To date, the role of iron in carbon cycling has largely been assessed using short-term iron-addition experiments. It is difficult, however, to reliably assess the magnitude of carbon export to the ocean interior using such methods, and the short observational periods preclude extrapolation of the results to longer timescales. Here we report observations of a phytoplankton bloom induced by natural iron fertilization--an approach that offers the opportunity to overcome some of the limitations of short-term experiments. We found that a large phytoplankton bloom over the Kerguelen plateau in the Southern Ocean was sustained by the supply of iron and major nutrients to surface waters from iron-rich deep water below. The efficiency of fertilization, defined as the ratio of the carbon export to the amount of iron supplied, was at least ten times higher than previous estimates from short-term blooms induced by iron-addition experiments. This result sheds new light on the effect of long-term fertilization by iron and macronutrients on carbon sequestration, suggesting that changes in iron supply from below--as invoked in some palaeoclimatic and future climate change scenarios--may have a more significant effect on atmospheric carbon dioxide concentrations than previously thought. 相似文献
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G Durand J P Dumont M Appel D Durand J Davy J Féger J Agneray 《Comptes rendus des séances de l'Académie des sciences. Série D, Sciences naturelles》1979,288(5):523-526
Hepatocytes isolated from streptozotocin treated Rats bind less asialotransferrin than hepatocytes isolated from normal rats. This decrease is parallel with a decrease in the sialic acid content. Insulin therapy restored simultaneously membrane sialic acid content and asialotransferrin binding capacity. 相似文献
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Dictyostelium discoideum cells shed vesicles with associated DNA and vital stain Hoechst 33342 总被引:2,自引:0,他引:2
I. Tatischeff M. Bomsel C. de Paillerets H. Durand B. Geny D. Segretain E. Turpin A. Alfsen 《Cellular and molecular life sciences : CMLS》1998,54(5):476-487
Dictyostelium discoideum cells are highly resis tant to xenobiotics. We previously observed that these primitive eukaryotic cells contain a 170-kDa
P-glycoprotein, mediating multidrug resistance in mammalian cells, but nonfunctional in Dictyostelium cells. We show here that D. discoideum cells vitally stained with the DNA-specific dye, Hoechst 33342, release fluorescent material in their culture medium. Electron
microscopy and lipid analysis demonstrate the vesicular nature of this material. Moreover, nucleic acids associate with these
extracellular vesicles independently of Hoechst vital staining. The main vesicular DNA component exhibits a size >21 kb. Shedding
of microvesicles during cell growth is not concomitant with programmed cell death. We propose that these extracellular vesicles
are involved in a new cellular resistance mechanism against xenobiotics. Furthermore, since the association of DNA with vesicles
occurs in physiological growth conditions and independently of vital staining, the new shedding process might be involved
in a more general intercellular mechanism.
Received 14 November 1997; received after revision 16 March 1998; accepted 16 March 1998 相似文献
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P. Scarmato C. Cherqui-Eisenberg G. Durand J. Feger 《Cellular and molecular life sciences : CMLS》1989,45(5):480-482
Summary The binding of asialoglycoproteins by hepatic binding protein was studied in freshly isolated hepatocytes from genetically diabetic BB Wistar rats. The number of cell surface asialoglycoprotein receptors was dramatically decreased (58,000±38,000 for diabetic rats compared to 267,000±70,000 for normal rats), while the association equilibrium constant was not changed. These results parallel those obtained with streptozotocin-diabetic rats and support the hypothesis that insulin deprivation is responsible for the decrease in the receptor number. 相似文献