Efficient statistical analysis method of power/ground(P/G) network

In this paper, we propose an incremental statistical analysis method with complexity reduction as a pre-process for on-chip power/ground (P/G) networks. The new method exploits locality of P/G network analyses and aims at P/G networks with a large number of strongly connected subcircuits(called strong connects) such as trees and chains. The method consists of three steps. First it compresses P/G circuits by removing strong connects. As a result, current variations (CV) of nodes in strong connects are transferred to some remaining nodes. Then based on the locality of power grid voltage responses to its current inputs, it efficiently calculates the correlative resistor (CR) matrix in a local way to directly compute the voltage variations by using small parts of the remaining circuit. Last it statistically recovers voltage variations of the suppressed nodes inside strong connects. This new method for statistically compressing and expanding strong connects in terms of current or voltage variations in a closed form is very efficient owning to its property of incremental analysis. Experimental results demonstrate that the method can efficiently compute low-bounds of voltage variations for P/G networks and it has two or three orders of magnitudes speedup over the traditional Monte-Carlo-based simulation method, with only 2.0% accuracy loss.     

Mediators of vascular remodelling co-opted for sequential steps in lung metastasis

Metastasis entails numerous biological functions that collectively enable cancerous cells from a primary site to disseminate and overtake distant organs. Using genetic and pharmacological approaches, we show that the epidermal growth factor receptor ligand epiregulin, the cyclooxygenase COX2, and the matrix metalloproteinases 1 and 2, when expressed in human breast cancer cells, collectively facilitate the assembly of new tumour blood vessels, the release of tumour cells into the circulation, and the breaching of lung capillaries by circulating tumour cells to seed pulmonary metastasis. These findings reveal how aggressive primary tumorigenic functions can be mechanistically coupled to greater lung metastatic potential, and how such biological activities may be therapeutically targeted with specific drug combinations.     

A giant outburst two years before the core-collapse of a massive star

The death of massive stars produces a variety of supernovae, which are linked to the structure of the exploding stars. The detection of several precursor stars of type II supernovae has been reported (see, for example, ref. 3), but we do not yet have direct information on the progenitors of the hydrogen-deficient type Ib and Ic supernovae. Here we report that the peculiar type Ib supernova SN 2006jc is spatially coincident with a bright optical transient that occurred in 2004. Spectroscopic and photometric monitoring of the supernova leads us to suggest that the progenitor was a carbon-oxygen Wolf-Rayet star embedded within a helium-rich circumstellar medium. There are different possible explanations for this pre-explosion transient. It appears similar to the giant outbursts of luminous blue variable stars (LBVs) of 60-100 solar masses, but the progenitor of SN 2006jc was helium- and hydrogen-deficient (unlike LBVs). An LBV-like outburst of a Wolf-Rayet star could be invoked, but this would be the first observational evidence of such a phenomenon. Alternatively, a massive binary system composed of an LBV that erupted in 2004, and a Wolf-Rayet star exploding as SN 2006jc, could explain the observations.     

高吞吐量协作防火墙的双向去冗余方法

针对协作防火墙中冗余规则会降低其吞吐量的问题,提出一种基于双向去冗余的高吞吐量协作防火墙优化方法.该方法通过比对协作防火墙中双方的防火墙规则,双向去除域内防火墙之间的冗余规则,提高整个协作防火墙的数据包过滤能力.仿真实验结果表明,该方法的冗余率达到了22.7％,提高了8.2％吞吐量,明显优于已有协作防火墙优化方法.     

Role of metallothioneins in peripheral nerve function and regeneration

The physiological role of the metallothionein (MT) family of proteins during peripheral nerve injury and regeneration was examined in Mt1+ 2 and Mt3 knockout (KO) mice. To this end, the right sciatic nerve was crushed, and the regeneration distance was evaluated by the pinch test 2-7 days postlesion (dpl) and electrophysiologically at 14 dpl. The quality of the regeneration was assessed by light microscopy and immunohistochemical methods. The results show that the regeneration distance was greater in the Mt3 KO than in the Mt1+ 2 KO mice, whereas control mice showed intermediate values. Moreover, the number of regenerating axons in the distal tibial nerve was significantly higher in Mt3KO mice than in the other two strains at 14 dpl. Immunoreactive profiles to protein gene product 9.5 were present in the epidermis and the sweat glands of the plantar skin of the hindpaw of the Mt3 KO group. The improved regeneration observed with the Mt3 KO mice was confirmed by compound nerve action potentials that were recorded from digital nerves at 14 dpl only in this group. We conclude that Mt3 normally inhibits peripheral nerve regeneration.     

西太平洋热带气旋路径对北京PM10污染的预示作用

利用北京地区空气质量监测资料和NCEP再分析资料, 分析了北京地区PM10污染过程与天气形势和天气系统的关系. 特别是通过对海平面气压场和西太平洋热带气旋路径的分析, 发现西太平洋热带气旋路径对北京地区PM10污染的发生具有预示作用, 即当热带气旋北上并在朝鲜半岛或日本登陆的情况下, 北京地区一般受持续均压场等弱中尺度天气系统控制, 经常容易发生区域性的PM10空气污染过程. 这为开展北京空气污染预报预警和污染控制, 提供了一个有效的预报方法和手段.     

三维杂金属(3d-4f)配位聚合物: {[Ln2Cu(pydc)4(H2O)6]•2H2O}n的合成与结构

在水热条件下(160℃), 通过稀土氧化物(Ln₂O₃)、氯化铜(CuCl₂)与2,5-吡啶二甲酸(H₂pydc)反应合成了两个新颖的3d-4f配位聚合物{[Ln₂Cu(pydc)₄(H₂O)₆]•2H₂O}_n [Ln = Eu(1)和Gd(2)]. X射线晶体学研究表明, 配位聚合物(1)和(2)是同晶异质体, 都具有开放的三维网状结构. 晶体结构和热重分析结果都表明在配位聚合物内存在较强的氢键相互作用.     

内电解预处理提高酵母废水可生化性机理研究

内电解预处理可以提高酵母废水的可生化性, 利用紫外扫描(UV)、渗透凝胶色谱(GPC)、气相色谱-质谱(GC-MS)等方法对处理前后废水中有机物的紫外吸收、分子量分布及化学组成等特性进行了研究. 旨在探讨内电解预处理法提高废水可生化性的机理. 研究结果表明: (ⅰ) 内电解过程中有机物可能通过分解, 水解使复合物简单化, 使环状物质开环, 分解或部分开环变为链状物质, 大分子物质裂解断链变为小分子物质, 生成的物质含有推电子基团的物质增多, 可生化性有所增强; (ⅱ) 原水中及内电解过程中生成的小分子的酸、醇等易降解的有机化合物可以通过挥发、电化学聚集等方式去除, 而其去除使废水COD降低, 从而B/C值提高.     

双圆环形超深基坑支护结构的数值模拟与监测分析

结合某锚碇基础双圆环形超深基坑支护结构的工程实例,采用全三维有限元分析方法模拟整个基坑的施工开挖过程,考虑土和支护结构的相互作用,并结合现场的监测数据进行对比分析,得出了双圆环形超深基坑支护结构的变形特征和受力特性,以及周围土体的变形特征和塑性区分布.从结果看出双圆环形超深基坑具有明显的空间效应和拱效应特点,按照传统方法进行设计是偏于保守的;同时因双圆环形超深基坑支护结构本身变形较小,所以内衬由于地下连续墙位移而产生的内力并不占主导地位,而施工期间的温度变化等其他因素对其受力有很大影响,因而,内衬环向应力基本以受拉为主.