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51.
Mengyang Liu Yuanli Chen Xiaoxiao Yang Ling Zhang Tao Zhao Buchang Zhao Lifu Jia Yan Zhu Xiumei Gao Boli Zhang Xiaoju Li Rong Xiang Jihong Han Yajun Duan 《科学通报(英文版)》2014,59(13):1366-1373
Clinical observations indicate that DanHong Injection (DHI) can increase blood flow and reduce various syndromes in patients with cardiovascular disease. How- ever, it still needs to define the function of DHI and the involved mechanisms in details, such as the protective effect on the development of primary abdominal aortic aneurysms (AAAs). In this study, we determined whether DHI is able to inhibit AAA in apoE knockout (apoE-/-) mice. Thirty apoE-/- male mice on high-fat diet (0.5 % cholesterol, 21% fat) were randomly divided into two groups and received i.p. injection of saline (100 μL/day) and DHI (100 μL/day), respectively, for 16 weeks. At the end of experiment, we determined the development of atherosclerosis in en face aorta and aneurysms,pathological morphology of arterial wall, and serum lipid levels. We also determined the expression of monocyte chemoattractant protein-1 (MCP-1), MMP-2, and MMP-9 mRNA in aortic wall using real-time RT-PCR. Our results indicated that high-fat diet induced the development of AAAs in apoE-/- mice, but the induction was totally blocked by DHI (P 〈 0.01). The result of staining of abdominal aortic cross sections showed that DHI main- tained the collagen content in arterial wall, thereby pre- venting the animals from the development of AAA. Although DHI had little effect on serum total- and LDL- cholesterol levels, it reduced the expression of MCP-1, MMP-2, and MMP-9 mRNA in aortic wall (P 〈 0.01). Taken together, our study suggests that DHI can inhibit the high-fat diet-induced AAA formation. The inhibitory effects may be related to the maintenance of the collagen content and inhibition of expression of AAA-related genes. Our study may suggest a new application of DHI in clinics. 相似文献
52.
段立松 《南京大学学报(自然科学版)》2014,(1):6-7,67
概述了氨酸法料床直接反应工艺的特点,并提出其后续优化措施,即将浓硫酸的稀释热用于液氨的汽化或将部分原料加热熔融生成料浆,采用两段湿法洗涤的手段对造粒尾气、干燥尾气和冷却尾气进行综合治理。采用上述改进措施后,能进一步提高热量的利用水平,明显提高了尾气的净化效果,实现洗涤液零排放。 相似文献
53.
Xueling Shi Tao Chen Lingqian Zhang Suping Duan Jiang Liu Zhaohai He 《科学通报(英文版)》2014,59(34):4790-4796
An ion flux dropout near the dipolarization front (DF) at around XGSM =- 11 RE in the Earth' s plasma sheet was observed by Time History of Events and Macroscale Interaction during substorms (THEMIS) on March 31, 2009. The ion differential energy fluxes at energies from 450 eV to 150 keV measured by the ESA and SST instruments from THC began to decrease about 2 s before the detection of the DF and reached a local minimum 6 s later. Then, the ion fluxes gradually increased to form a dropout around the DF. The spatial extent of the dropout was about 4,000 km. For energies above 20 keV, the ion fluxes after the dropout are greater than those before it, contrary to the fluxes at energies below 20 keV. The associated ion density variation indicates that the ion flux dropout coincides with the ion density dropout. Taking advantage of multipoint observations, THD, THC, and THE detected the same DF consecutively. Only THC detected an obvious ion flux dropout; THD observed an indistinct one about 2 s before THC; no high-energy (E 〉 30 keV) ion flux dropout was observed by THE. Our study suggests that the ion flux dropout may evolve with the earthward-propagating DF, and its properties can depend on locations relative to the DF. 相似文献
54.
用模型论的方法证明了一类不定方程a1xr11 a2xr22 ... anxrnn=bys(其中a1,...,an,b为任意整数,r1,...,rn,s为任意正整数)有解.进一步地,我们用相同的方法解决了一个猜想. 相似文献
55.
干线协调交叉口多相公交信号优先控制策略 总被引:1,自引:0,他引:1
针对干线协调交叉口多个相位有公交车到达的情况,为降低公交车延误,建立了以不破坏协调绿波带为前提的多相位公交优先控制策略.在该策略中,提出了“就近原则”以解决多个相位的公交优先申请冲突,对公交优先级别进行排序,并建立了多相位公交优先控制流程;考虑最高优先级别公交车的不同相位属性,采用绿灯延长和绿灯提前起亮两种优先方式,分... 相似文献
56.
Coalbed methane (CBM) accumulation models include continuous gas accumulation and staged gas accumulation.However,studied on the geochemical characteristics and indices to evaluate staged accumulation CBM are lacking.This study for the first time obtained the carbon and hydrogen isotopic compositions of methane and ethane generated at different evolution stages using thermal simulation of samples prepared by treating an herbaceous swamp peat at different temperatures.The results showed that the carbon isotopic compositions of methane and ethane were obviously affected by the thermal evolution level of the starting sample,while the hydrogen isotopic compositions were closely related to the maturity of gases.The carbon and hydrogen isotopic compositions of gases generated by coal-forming organic matter with Ro values from 1.2%,1.7%,2.4%,3.2% and 3.7% to 5.2% were determinated.The relationship between Ro values and the carbon and hydrogen isotopic compositions of gases generated by coal-forming organic matter at different evolution stages as well as the carbon or hydrogen isotopic relationships between methane and ethane were established.The results provide a scientific basis for studying the genesis of CBM generated at different maturity intervals and understanding the geochemical characteristics of staged accumulation CBM.These results were applied to a case study on CBM from the southern Qinshui basin,and it was found that the CBM accumulated after the Middle Jurassic and was characteristic of staged gas accumulation.This is consistent with the result of geological studies,and further showed that the results of thermal simulation experiments are very important for evaluating the genesis of natural CBM. 相似文献
57.
火车是目前交通运输能力最强的交通工具之一,火车的运输能力使火车站周边经济能够迅速繁荣起来.如何通过火车站的效益带动周边经济,实现火车站经济圈增长对于我国社会经济具有重要的促进作用.本文在相关理论的基础上,分析了我国现行发展状况下火车站经济圈建设的必要性与意义,同时制定了符合我国实际的发展对策. 相似文献
58.
110kV分段及备投保护屏由四方继保CSC-215母联充电保护装置和CSC-246备用电源投切装置组成.CSC-215保护方面的主要功能有:①短充电流保护、零流保护;②长充电过流、零流保护.CSC-246备投方面的主要功能有:①线路备投方案;②变压器备教方案;③可编程方式制定特殊的备投方式;④备投逻辑中充放电自动完成. 相似文献
59.
在市场经济体制下,招投标管理对公路桥梁施工起到了极大的促进作用,文章从招投标管理的积极作用入手,分析了现阶段招投标管理的一些问题,并提出建议。 相似文献
60.
两点边值问题Daubechies小波δ-序列数值解法 总被引:1,自引:0,他引:1
使用广义函数δ-序列方法数值求解两点边值问题.这种δ-序列以Daubechies小波为基础,具有紧支、对称、拟插值的性质.以对流占优方程为例,空间导数采用Daubechies小波δ-序列作数值格式离散,验证了该方法的有效性.使用Daubechies小波δ-序列数值方法求解两点边值问题,方法简单,能方便地处理各类边值问题,计算精度高.数值算例表明,Daubechies小波δ-序列数值方法不仅能够较好地求解具有边界层的两点边值问题,而且可以非常方便地求解具有较高阶导数的梁、板等力学问题. 相似文献