自焙碳砖-陶瓷砌体非稳态热传导特点的数学模型分析

测定了高炉用自焙碳砖在其自焙烧过程中,导热系数随时间变化规律及其它物理性质·结果表明,自焙碳砖自焙烧过程中导热系数λ与焙烧时间τ可表示为λ＝３８３４５＋０００１４３τ·结合鞍钢７＃高炉生产数据,建立了自焙碳砖 陶瓷砌体非稳态热传导的数学模型,并采用数值分析方法对该模型进行了分析求解·其结果表明该模型与实际生产情况比较吻合,除炉底中心部位之外,炉缸耐火材料内衬８００℃以上等温线随自焙碳砖石墨化程度的提高逐渐上移至陶瓷砌体层内,从温度场分布角度上看,新型炉缸结构将消除传统结构炉缸所存在弊端,有助于高炉长寿·     

Key technology for construction of connection between steel pylon and concrete pile cap of middle pylon of Taizhou Bridge

Taizhou Yangtze River Bridge is a suspension bridge with three pylons and two 1080m main spans. The middle pylon is a steel frame with longitudinal herringbone shape and lateral gate shape. The connection between steel pylon and concrete pile cap is a key part to transfer the huge inner force from the pylon to the foundation. Its construction quality is a critical factor to the overall structural loading of the whole bridge, therefore the contact ratio between the bearing steel plate of pylon and concrete pile cap is required to be over 75%. The inclined joint surface in two directions, longitudinally at 39/1920 and laterally at 1/4, posted a challenge to the construction works. Technological tests were carried out to find an optimal construction method by comparison, and finally the Post-Injection method was selected as it can meet the requirement of concrete strength and contact ratio at the connection. The successfully application of the Post-Injection method at Taizhou Yangtze River Bridge has provided an example and reference for similar projects in the future.     

风速对浇筑期轻质泡沫混凝土性能的影响

为了探究风速在浇筑期对轻质泡沫混凝土（lightweight cellular concrete,LCC）性能的影响规律,设计模拟风速的室内试验研究了LCC宏观性能和微观结构的演变规律,并揭示了微孔结构参数与宏观性能参数之间的相互关系。结果表明：当风速在4级风以下和持续时间在6 h以内,LCC干密度和抗压强度均与风速呈正相关,吸水率与风速呈负相关;等效孔径和平均孔圆周度与风速呈负相关,孔径分布符合对数正态分布,气孔逐渐趋于有利于受力特性的圆形;风速对孔隙分布分维影响不大,但总体趋势也是与孔分布分维呈负相关。可见,在4级风以下和持续时间较短（6 h以内）时,风速增长、时间延长总体上对LCC各项性能起优化作用。     

一种支持TCAM规则更新与压缩方法

提出了一种TCAM空间划分和规则压缩相结合的方法,使得OpenFlow网络在支持实时更新的同时能采用小容量的TCAM芯片来存储网络中的规则.所提方法将TCAM芯片空间划分为实时更新区和压缩存储区,实时更新区处在TCAM芯片的前部,用于存放中央控制器发送过来的实时更新规则.后台服务器以一定的时间周期将TCAM芯片中的实时更新区的规则以及压缩存储区中的规则进行压缩,并将压缩后的规则存入TCAM的压缩区,保持实时更新区具有空间接收实时更新规则.分析了区间划分的比率问题,并利用ClassBench工具产生原始规则集进行了仿真实验,实验结果验证了本文方法的有效性.     

论网络环境下的知识产权保护

随着网络的迅猛发展 ,网络环境下的知识产权保护问题也日益显得突出。文章就网络环境下的知识产权保护问题提出了一些对策     

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

Although AKT1 (v-akt murine thymoma viral oncogene homologue 1) kinase is a central member of possibly the most frequently activated proliferation and survival pathway in cancer, mutation of AKT1 has not been widely reported. Here we report the identification of a somatic mutation in human breast, colorectal and ovarian cancers that results in a glutamic acid to lysine substitution at amino acid 17 (E17K) in the lipid-binding pocket of AKT1. Lys 17 alters the electrostatic interactions of the pocket and forms new hydrogen bonds with a phosphoinositide ligand. This mutation activates AKT1 by means of pathological localization to the plasma membrane, stimulates downstream signalling, transforms cells and induces leukaemia in mice. This mechanism indicates a direct role of AKT1 in human cancer, and adds to the known genetic alterations that promote oncogenesis through the phosphatidylinositol-3-OH kinase/AKT pathway. Furthermore, the E17K substitution decreases the sensitivity to an allosteric kinase inhibitor, so this mutation may have important clinical utility for AKT drug development.     

透明土物理模拟试验技术现状与趋势

透明土物理模拟试验技术是研究解决岩土工程基础科学与工程技术问题的重要手段之一.对当前透明土物理模拟试验技术的基本原理、主要内容、工程应用以及当前存在问题与未来发展趋势进行了系统归纳与总结分类.研究发现:利用激光制斑的透明砂土可以二次复用,极大地降低了实验成本;在透明度确定的原则下可以适当增大模型尺寸以减小边界效应带来的...     

Surface PEGylation of hollow mesoporous silica nanoparticles via aminated intermediate

A hybrid of organic/inorganic system, hollow mesoporous silica nanoparticles functionalized with poly(ethylene glycol), was synthesized in the presence of coupling agent and aminated ends. Doxorubicin (DOX) was used as a model drug to evaluate the effect of PEGylation on the loading capacity and release pattern of the system. Characterization with transmission electron microscopy (TEM) and scanning electron microscopy (SEM), X-ray diffraction (XRD), nitrogen adsorption-desorption, thermogravimetric analysis (TGA) and Fourier transformed infrared (FTIR) confirmed the PEG conjugation, as well as the amorphous mesoporous nature of the synthesized particles. Due to the capping effect of PEG molecules over the pores in the silica structure, the synthesized system was able to retain higher amount of cargo and establish a controlled manner when releasing.     

天津市软土地层地铁盾构区间下穿施工对京沪高铁南仓特大桥影响的数值分析

为研究天津地区软土地层隧道盾构区间下穿施工对京沪高铁南仓特大桥的影响,以下穿京沪高铁的天津地铁7号线外院附中站-榆关道站区间隧道工程为背景,对下穿京沪高铁南仓特大桥段区间盾构隧道进行设计,通过运用Midas/GTS有限元软件数值分析方法对盾构区间下穿京沪高铁南仓特大桥进行有限元数值分析。研究盾构区间下穿京沪高铁南仓特大桥施工过程中桥面、桥墩、承台及桥桩位移变化规律特征。总结盾构区间侧穿桥桩施工过程中桥桩附加应力变化规律;揭示了盾构区间下穿京沪高铁特大桥施工过程中承台差异沉降及地层应力变化规律。结果表明,盾构隧道施工过程中京沪高铁天津南仓特大桥桥桩附加弯矩较小,桥面、承台、桥墩及桥桩沉降最大值均在控制标准值范围以内,桥桩水平位移最大值在控制标准值范围以内,不会对大桥产生破坏影响。可见在软土地区盾构施工对高铁特大桥有一定程度影响,但通过施加工程措施后,可有效降低对桥的影响程度,保证高铁桥的安全。研究成果可为类型工程施工设计提供参考。     

黔东南下古生界碳酸盐岩台地演化

位于上扬子地块东南缘的黔东南石阡地区,下古生界地层连续发育,地质现象丰富,是研究扬子台地演化最有利的地区之一。根据野外勘查、实测剖面以及镜下薄片观察资料,识别出陆棚相、台地边缘相、台地相、潮坪相4种沉积相类型,并对扬子碳酸盐岩台地的演化过程进行精细刻画,建立其台地演化模式,研究台地由出现至成熟至衰亡的发展过程。结果表明,黔东南地区下古生界碳酸盐岩台地演化经历过建设期、发展期、逆演化期3个明显阶段。第二世早期(清虚洞组沉积期)黔南地区开始出现碳酸盐岩沉积,晚期完整的台、坡、盆格局形成;特马豆克期,碳酸盐岩沉积累计厚度达千余米,为发展期的顶峰;早奥陶世大坪期,受郁南运动影响,黔东地区由局限台地向开阔台地转变,受郁南运动的持续影响,台地逐渐向缓坡相过渡,沉积了大套的碎屑岩以及碎屑岩与碳酸盐岩混积的缓坡相岩石组合,拉开了碳酸盐岩台地逆向的序幕。晚奥陶世末,黔中隆起、雪峰隆起相继形成,毕节—遵义—石阡—铜仁一线以南抬升遭受剥蚀,五峰组、龙马溪组地层缺失,中上扬子碳酸盐岩台地的演化迎来终结。