Influences of ultrasonic irradiation on the morphology and structure of nanoporous Co nanoparticles during chemical dealloying

The Co-61.8 wt% Al nanoparticles of 45 nm were prepared by hydrogen plasma-metal reaction (HPMR) method. The nanoparticles display core shell structure with Al13Co4 and CoAl core and aluminum oxide shell (about 2 nm). Under ultrasonic irradiation, nanoporous fcc-Co nanoparticles were produced successfully by chemically dealloying the Co-Al nanoparticles at room temperature, whereas, without ultrasonic irradiation CoAl phase could hardly react with sodium hydroxide solution. At 323 K the Co-Al nanoparticles could be dealloyed to fcc-Co and hcp-Co phases even without ultrasonic irradiation. The surface area of the dealloyed nanoparticles under ultrasonic irradiation was larger than that of the dealloyed sample without ultrasonic irradiation at the same temperature. It is believed that the microjet and shock-wave induced by ultrasonic irradiation give rise to particles size reduction, interparticle collision and surface cleaning, and accelerate the dealloying process and the phase transformation.     

Epithelial-cell-intrinsic IKK-beta expression regulates intestinal immune homeostasis

Intestinal epithelial cells (IECs) provide a primary physical barrier against commensal and pathogenic microorganisms in the gastrointestinal (GI) tract, but the influence of IECs on the development and regulation of immunity to infection is unknown. Here we show that IEC-intrinsic IkappaB kinase (IKK)-beta-dependent gene expression is a critical regulator of responses of dendritic cells and CD4+ T cells in the GI tract. Mice with an IEC-specific deletion of IKK-beta show a reduced expression of the epithelial-cell-restricted cytokine thymic stromal lymphopoietin in the intestine and, after infection with the gut-dwelling parasite Trichuris, fail to develop a pathogen-specific CD4+ T helper type 2 (T(H)2) response and are unable to eradicate infection. Further, these animals show exacerbated production of dendritic-cell-derived interleukin-12/23p40 and tumour necrosis factor-alpha, increased levels of CD4+ T-cell-derived interferon-gamma and interleukin-17, and develop severe intestinal inflammation. Blockade of proinflammatory cytokines during Trichuris infection ablates the requirement for IKK-beta in IECs to promote CD4+ T(H)2 cell-dependent immunity, identifying an essential function for IECs in tissue-specific conditioning of dendritic cells and limiting type 1 cytokine production in the GI tract. These results indicate that the balance of IKK-beta-dependent gene expression in the intestinal epithelium is crucial in intestinal immune homeostasis by promoting mucosal immunity and limiting chronic inflammation.     

纤维素酶液中β-葡萄糖苷酶的分离纯化

通过(NH4)2SO4分级沉淀、HiPrep 26/10 Desalting脱盐柱、Source15Q阴离子交换柱、Source 15 S阳离子交换柱、HiTrap 16/60 Sephacryl S 200 HR凝胶过滤等技术,分离纯化3种来源里氏木霉、黑曲霉、里氏木霉与黑曲霉混合纤维素酶液中的β-葡萄糖苷酶。结果表明,经SDS PAGE电泳鉴定均为电泳纯,测得黑氏木霉、黑曲霉单独培养β-葡萄糖苷酶相对分子质量分别为68、129 ku,而混合菌培养分离得到两种β-葡萄糖苷酶分子质量大小分别为66.2、134 ku。与单独培养的β-葡萄糖苷酶相似。3种来源的β-葡萄糖苷酶经多步分离纯化后的纯化倍数分别为37.25、40.21、30.12,酶活回收率分别为20.1 2%、23.21 %、28.56 %。     

退火温度对用PⅢ方法制备共掺杂p型ZnO薄膜结构和性能的影响

采用射频磁控共溅射的方法制备出ZnO:Al薄膜,以NO和O2为源气体(V(O2)/V(O2+NO)=75%),采用等离子体浸没离子注入(PⅢ)方法对薄膜进行注入得到ZnO:Al:N薄膜,注入剂量为2.23×1015 cm-2,并在N2氛围下对样品进行了不同温度的退火处理.通过XRD图谱、霍尔效应(Hall)测试结果、紫外-可见光透射光谱等对样品的结构和性能进行了分析,着重研究了退火温度对ZnO:Al:N薄膜性质的影响.结果表明,退火可以使注人产生的ZnO(N2)3团簇分解,并且使N以替位O的方式存在.当退火温度达到850℃时,ZnO薄膜实现了p型反转,实现p型反转的ZnO:AliN薄膜载流子浓度可达3.68×1012cm-3,电阻率为11.2 Ω·cm,霍耳迁移率为31.4 cm2·V-1·s-1.     

圆弧空间曲线梁架钢结构施工技术

天津霍元甲纪念馆工程为圆形钢结构仿古建筑,圆弧钢梁采用热轧H型钢制作,本文论述了圆弧空间复杂曲线钢梁施工的技术难点、施工方法。     

圆弧空间曲线梁架钢结构施工技术

天津霍元甲纪念馆工程为圆形钢结构仿古建筑,圆弧钢梁采用热轧H型钢制作,本文论述了圆弧空间复杂曲线钢梁施工的技术难点、施工方法.     

上跨既有高速公路现浇连续箱梁门洞支架施工技术

上跨既有高速公路桥梁施工越来越普遍,其中,钢管立柱与工字钢梁组合门洞支架法运用于现浇桥梁上跨既有道路已是相当成熟的技术,其施工工艺简单、受力明确、操作方便,在建平阳高速太原枢纽互通中BK0+563.5跨线桥上跨原太高速公路即采用该法进行现浇梁施工。文章以该次上跨为例,详细介绍了门洞支架在保证通车的条件下搭设、拆除的施工工艺。     

人性化管理在医学图书馆中的应用

当前,随着我国信息技术发展速度的不断加快,我国医学图书馆的服务观念已从单纯的读者服务转向协调、合作、共享的服务模式。我国医学图书馆正在向信息增值型、产业型以及服务型的方向发展。将人性化管理理念运用于医学图书馆管理中来,就是一种以围绕人的生活、工作习性展开研究,使现代医学图书馆在管理过程中能够更加贴近人性,满足人的多样化需求,从而更有效地提高工作效率。     

多目标规划纯量化问题的Lipschitz稳定性

利用Kojima函数的正则性质研究了多目标规划问题的纯量化问题解的强Lipschitz稳定性．     

一类奇异微分方程边值问题的数值方法

在再生核空间中讨论一类二阶奇异微分方程两点边值问题.研究方程解存在的充分性和解唯一的必要性,建立解的精确表达式,获得近似解的求解方法,数值模拟结果说明该方法的有效性.