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61.
XIEKe TIANLing DENGHongxin WEIYuquan 《科学通报(英文版)》2003,48(11):1051-1054
Tumor antigen is one of the important bases of tumor immunotherapy . With the discovery of novel tumor antigens, interest in specific immunotherapy for treatment of malignancies has increased substantially. Nowadays more and more scientists paid close attention to various tumor antigens with their roles or/and applications in anti-cancer immune responses, immune tolerance, tumor markers, 相似文献
62.
Lu Wei-bing Wang Cun-xin Deng Li-zhi Zhou Xiao-hai Ren Jian-guoCollege of Chemistry Molecular Sciences Wuhan University Wuhan Hubei China 《武汉大学学报:自然科学英文版》2003,8(2):428-432
A new dinucleating ligand having two metal-binding sites has been designed and synthesized as model ligand for Cytochrome c Oxidase. The corresponding heterodi-nuclear complex, as an active site model of Cytochrome c Oxidase, consisting of a porphyrinatocobalt compound covalently linked with a copper derivative of tris(2-benzimidazylmethyl) amine bearing three benzimidazole ligands for copper was synthesized and spectroscopically characterized. The spectra data suggest that there are interactions between the cobalt and copper coordination units. The cobalt is coordinated to four central nitrogens of the porphyrin and the copper has pentaco-ordinate geometry with the four tertiary amine nitrogens and a chloride. 相似文献
63.
Deng Ren-qing Liu Qing-hua Zhang Hu-shengCollege of Physical Science Technology Wuhan University Wuhan Hubei China Department of electric computer engineering National University of Singapore Singapore Singapore 《武汉大学学报:自然科学英文版》2003,8(2):463-466
Ultralow frequency (ULF) pulsed-gradient magnetic field (with the maximum intensity of 0.6-2.0 T, gradient of 10-100 T·m-1, pulse width of 20-200 ms and frequency of 0. 16-1. 34 Hz) treatment of mice can inhibit murine malignant tumour growth and can induce apoptosis of cancer cell. The apoptotic cancer cell contracted, became rounder and divorced from adjacent cells; the heterochromatin condensed and coagulated together along the inner side of the nuclear membrane; the endoplasmic reticulums expanded and fused with the cellular membrane; many apoptotic bodies which were packed by the cellular membrane appeared and were devoured by some lymphocytes and plasma. By Lorentz force the magnetic field keeps the moving ions within bounds of Larmor radius. Thus, penetrating capability of the positive and negative ions through the cell membrane was affected, even the role on the cell membrane formed. 相似文献
64.
论述了过采样 Σ- ΔADC的基本原理及结构 ,分析了 Σ- Δ调制器的频域传输特性和系统的信噪比 ,给出了实现不同的 A/D转换精度必须满足的条件和用单片机实现 Σ- ΔADC的具体方法和电路 .实际使用表明 ,该方法测量结果可靠 ,具有实用价值 相似文献
65.
本文详细介绍了如何把AutoCAD绘制的图形插入到Word文档;如何把Excel制作的表格插入到AutoCAD图形中,并转换成AutoCAD图元以及对象选择的几种方式。 相似文献
66.
NIEYuchun KEYeyan WANGZai YUXiang DENGHongkui DINGMingxiao 《科学通报(英文版)》2003,48(13):1352-1357
The L protein (241kD) of vesicular stomatitis virus (VSV) is the most important snbnnit of the replication complex. The existence of specific localization signal in the L protein was investigated by making recombinant constructs expressing truncated mutants of the L protein fused to green fluorescent protein (GFP) in transient transfection assays. The chimeric genes encoding varied N-terminal of L and GFP gene were put under the control of T7 promoter or CMV promoter. The fusion proteins were transiently expressed in BHK-21, COS-7, CHO or Hep G2 cells. When more than 120 residues were deleted or only 96 residues were kept on the N-terminal, the fusion proteins were shown to be distributed throughout the cells, cytoplasm and nucleus under the confocal microscope. However, other chimeric proteins with 120 or more amino acids were dotted and distributed in the perinuclear regions. And the fusion protein with 96—120 aa has the similar distribution. A thirteen-residue peptide QGYSFLHEVDKEA (108—120) was identified as localization signal, whose function would be absolutely distributed with the deficiency of D or V. Our results show that there is an independent localizing signal in N-terminal domain of L protein of VSV and this functional signal is conserved in different cell lines. 相似文献
67.
LIUHongyan TIANYuhong DINGDeng 《科学通报(英文版)》2003,48(17):1853-1856
Different land cover types in Otindag Sandy Land and Bashang area of Hebei Province are linked to a material source of sand stormy weather in Beijing based on results of field vegetation and soil survey and laboratory works. Results of grain size analysis show that dust release potential in per unit area of moving sandy land is small,while lowland meadow and meadow steppe in stony hills have high potential of releasing dusts in per unit area during sand stormy weather occurrence. Further considering the effects of vegetation, it is inferred that the moving sandy land served as a material source of past dust storm and the possibility of dust release in per unit area is low in current time.Typical steppe in stony hills is undergoing desertification and its dust release possibility in per unit area is high. Farmland has strong potential of release dusts when they are ploughed in spring, but a large amount of therophytes grow and thus prevent dusts from release when cultivation was terminated.Potentials of dust release in per unit area in fixed sand dunes,stony mountain meadow steppe and low land meadow are lowdue to high cover of perennials. Sand dune reactivation and desiccation of lakes and lowlands under estimated future climatic change will make them serve as a future material source of sand stormy weather. 相似文献
68.
基于GIS和VR的矿图数字化 总被引:3,自引:1,他引:3
从矿山系统工程角度,分析了矿图以及使用CAD技术实现其数字化工作的意义,探讨了矿图数字化建立在地理信息系统(GIS)和虚拟现实技术(VR)基础上的相关措施,讨论了进行该项工作需要使用的软件,目前基于GIS和VR的矿图数字化工作,已经取得了进展,进一步的研究有理论和应用方面的重要价值。 相似文献
69.
WASP6系统在三峡库区水质仿真中的应用 总被引:11,自引:0,他引:11
以1996—2002年三峡库区干流代表性断面水质监测资料为基础,运用WASP6系统对三峡库区水质进行了模拟与预测.结果表明,模拟值与实测值吻合较好,相对误差在15%以下的占92%;在维持现有污染负荷不变的情况下,蓄水前后水质变化不大,各断面水质均可达到地面水环境质量标准中的Ⅲ类或Ⅱ类水质标准;低水位运行的情况下,各断面的水质明显好于高水位运行情况. 相似文献
70.
从资源,固体废弃物,废水、废气,绿树、绿地等方面阐述了只有对环境因素进行全方位控制,才能实现最佳物业管理服务效用,创造优美、舒适、温馨的社区环境。 相似文献