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141.
This study examines an optimal inventory strategy when a retailer markets a product at different selling prices through a dual-channel supply chain, comprising an online channel and an offline channel. Using the operating pattern of the offline-to-online (O2O) business model, we develop a partial robust optimization (PRO) model. Then, we provide a closed-form solution when only the mean and standard deviation of the online channel demand distribution is known and the offline channel demand follows a uniform distribution (partial robust). Specifically, owing to the good structural properties of the solution, we obtain a heuristic ordering formula for the general distribution case (i.e., the offline channel demand follows a general distribution). In addition, a series of numerical experiments prove the rationality of our conjecture. Moreover, after comparing our solution with other possible policies, we conclude that the PRO approach improves the performance of incorporating the internet into an existing supply chain and, thus, is able to adjust the level of conservativeness of the solution. Finally, in a degenerated situation, we compare our PRO approach with a combination of information approach. The results show that the PRO approach has more “robust” performance. As a result, a reasonable trade-off between robustness and performance is achieved.  相似文献   
142.
Genome-wide association studies of 14 agronomic traits in rice landraces   总被引:20,自引:0,他引:20  
Huang X  Wei X  Sang T  Zhao Q  Feng Q  Zhao Y  Li C  Zhu C  Lu T  Zhang Z  Li M  Fan D  Guo Y  Wang A  Wang L  Deng L  Li W  Lu Y  Weng Q  Liu K  Huang T  Zhou T  Jing Y  Li W  Lin Z  Buckler ES  Qian Q  Zhang QF  Li J  Han B 《Nature genetics》2010,42(11):961-967
Uncovering the genetic basis of agronomic traits in crop landraces that have adapted to various agro-climatic conditions is important to world food security. Here we have identified ~ 3.6 million SNPs by sequencing 517 rice landraces and constructed a high-density haplotype map of the rice genome using a novel data-imputation method. We performed genome-wide association studies (GWAS) for 14 agronomic traits in the population of Oryza sativa indica subspecies. The loci identified through GWAS explained ~ 36% of the phenotypic variance, on average. The peak signals at six loci were tied closely to previously identified genes. This study provides a fundamental resource for rice genetics research and breeding, and demonstrates that an approach integrating second-generation genome sequencing and GWAS can be used as a powerful complementary strategy to classical biparental cross-mapping for dissecting complex traits in rice.  相似文献   
143.
磁盘表层润滑剂在磁头与磁盘之间转移会影响磁头飞行的稳定性.本文采用改进后的粗粒珠簧模型,运用分子动力学方法,研究了磁盘上类金刚石薄膜(diamondlikecarbon,DLC)层粗糙度和磁盘表面凸起对润滑剂在磁盘表面分布及磁头/磁盘之间润滑剂转移的影响.研究结果表明,DLC层粗糙度对润滑膜平均厚度及磁盘表层粗糙度的影响很小;磁盘表面凸起对磁盘表层润滑剂分布的影响明显.类金刚石薄膜层的粗糙度和磁盘表层凸起均可增加转移到磁头上的润滑剂的体积.但磁盘表层粗糙度对磁头/磁盘之间润滑剂转移量的影响明显低于由磁盘表层凸起导致的磁头/磁盘之间润滑剂的转移量.  相似文献   
144.
145.
Huang X  Zhao Y  Wei X  Li C  Wang A  Zhao Q  Li W  Guo Y  Deng L  Zhu C  Fan D  Lu Y  Weng Q  Liu K  Zhou T  Jing Y  Si L  Dong G  Huang T  Lu T  Feng Q  Qian Q  Li J  Han B 《Nature genetics》2012,44(1):32-39
A high-density haplotype map recently enabled a genome-wide association study (GWAS) in a population of indica subspecies of Chinese rice landraces. Here we extend this methodology to a larger and more diverse sample of 950 worldwide rice varieties, including the Oryza sativa indica and Oryza sativa japonica subspecies, to perform an additional GWAS. We identified a total of 32 new loci associated with flowering time and with ten grain-related traits, indicating that the larger sample increased the power to detect trait-associated variants using GWAS. To characterize various alleles and complex genetic variation, we developed an analytical framework for haplotype-based de novo assembly of the low-coverage sequencing data in rice. We identified candidate genes for 18 associated loci through detailed annotation. This study shows that the integrated approach of sequence-based GWAS and functional genome annotation has the potential to match complex traits to their causal polymorphisms in rice.  相似文献   
146.
研究了带有时变不确定性的It型随机系统的输出反馈镇定问题,采用变结构滑模控制(SMC)方法设计了镇定控制器.在系统的不确定性满足一定匹配条件的情况下,构造了对不确定性具有不变性以及参数不含噪声激励的滑模切换流形和变结构滑模控制律,分析和证明了滑模的可达性和闭环系统的稳定性,并给出了滑模控制律的参数选择条件.最后通过示例系统仿真实验证明了文中结果的正确性和有效性.  相似文献   
147.
当前大部分的聚类算法都难以处理任意形状和大小、存在孤立点和噪音以及密度多变的簇,为此,文中提出了一种基于连通图动态分裂的聚类算法.首先构造数据集的l-连通图,然后采用动态分裂策略对l-连通图进行分割,把数据集分成多个互不相连的连通图子集,每个连通图子集为一类.实验结果表明,所提出的算法能够有效地解决任意形状和大小、存在孤立点和噪音以及密度多变的簇的聚类问题,具有广泛的适用性.  相似文献   
148.
The problem of scalable classification by clustering in large databases was discussed. Clustering based classification method first generates clusters using clustering algorithms. To classify new coming da-ta points, it finds the κ nearest clusters of the data point as neighbors, and assign each data point to the dominant class of these neighbors. Existing algorithms incorporated class information in making clustering decisions and produced pure clusters (each cluster associated with only one class). We presented hybrid cluster based algorithms, which produce clusters by unsupervised clustering and allow each cluster associ- ated with multiple classes. Experimental results show that hybrid cluster based algorithms outperform pure ones in both classification accuracy and training soeed.  相似文献   
149.
利用传统方法,将Van Der Corput不等式的一个加强式做了改进,建立了Van Der Corput不等式两个更强的加强式,它们优于现有的众多结论.  相似文献   
150.
In this study, we selected 10 susceptible SNPs loci to investigate their contribution to susceptibility to type 2 diabetes in Han Chinese among Hubei population. We genotyped SNPs rs5219, rs1801282, rs1470579, rs1111875, rs1081661, rs7754840, rs4506565, rs13266634, rs4402960, and rs5643981 by using the method of polymerase chain reaction-ligase detection reaction (PCR-LDR). In a case-control study, we have genotyped the 10 candidate susceptibility SNP loci, and here, we reported that the SNP rs5219 in KCNJ1...  相似文献   
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