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821.
李德 《科技情报开发与经济》2008,18(28):226-227
从灵丘县基本情况和固城灌区发展现状出发,明确了灌区发展方向,同时结合当前农业灌溉出现的问题,提出了未来灌区发展的对策。 相似文献
822.
Carotenuto R De Marco N Biffo S Wilding M Vaccaro MC Marchisio PC Capriglione T Russo GL Campanella C 《Cellular and molecular life sciences : CMLS》2005,62(14):1641-1652
p27BBP/eIF6 is an evolutionarily conserved regulator of ribosomal function. It is necessary for 60S biogenesis and impedes improper joining of 40S and 60S subunits, regulated by protein kinase C or Efl1p. No data on p27BBP/eIF6 during early development of Metazoa are available. We studied the distribution, post-translational changes and association with the cytoskeleton of p27BBP/ eIF6 during Xenopus oogenesis and early development. Results indicate that p27BBP/eIF6 is present throughout oogenesis, partly associated with 60S subunits, partly free and with little cytoskeleton bound. During prophase I, p27BBP/eIF6 is detected as a single band of 27-kDa. Upon maturation induced by progesterone or protein kinase C, a serine-phosphorylated 29 kDa isoform appears and is kept throughout development to the neurula stage. Confocal microscopy showed that the distribution of p27BBP/eIF6 and its association with the cytoskeleton varies according to oogenesis stages. Briefly, in stage 6 oocytes, p27BBP/eIF6 has a limited dot-like distribution, and does not co-localize with cytokeratin, whereas upon maturation it spreads throughout the cytoplasm. After fertilization, a large fraction coalesces around cytomembranes and a cytochalasin B-sensitive co-localization with cytokeratin occurs. RNAse removes p27BBP/eIF6 from the cytokeratin fibres. Developmental data suggest a role of p27BBP/eIF6 in controlling ribosomal availability or regulating cross-talk between ribosomes and the cytoskeleton.Received 7 April 2005; received after revision 11 May 2005; accepted 25 May 2005R. Carotenuto and N. De Marco contributed equally to the paper 相似文献
823.
An integrative genomics approach to infer causal associations between gene expression and disease 总被引:2,自引:0,他引:2
824.
825.
826.
F. Couillaud A. B. Koopmanschap C. A. D. De Kort A. Girardie 《Cellular and molecular life sciences : CMLS》1987,43(3):312-314
Summary Hemolymph from adult femaleLocusta migratoria migratorioides was analyzed for binding of juvenile hormone III (JH-III) after allatectomy and transection of thenervus corporis allati 1 (NCA-I). These operations did not affect the apparent dissociation constant of the binding (Kd=3.3 10–8 M). The concentration of binding sites exhibited fluctuations in relation to age and type of operation: an increased concentration of binding sites in females with disconnected corpora allata and a decreased concentration in allatectomized females. The changes in concentration of binding sites was not due to differences in water content or hemolymph volume in operated animals. The hemolymph protein concentration was reduced after NCA-I transection and even more after allatectomy. However, variations in protein concentration did not correlate with changes in concentration of JH-III binding sites. The changes in binding site concentration were related to changes in JH-titer. 相似文献
827.
828.
On the stability of bilirubin 总被引:2,自引:0,他引:2
829.
830.