硫代磷酸三(4-马来亚酰氨基苯)酯的合成

以对乙酰氨基苯酚和三氯硫磷为原料,经过酯化反应、水解反应得到硫代磷酸三(4-氨基苯)酯(TPTA),再以TPTA和马来酸酐为原料,经过酰胺化反应得到硫代磷酸三(4-马来亚酰氨基苯)酯(TPTM),总产率达到76.5%.以红外光谱、质谱及核磁共振谱对各产物的结构进行了表征,结果表明该法成功合成了目标产物.对TPTM紫外光谱进行了初步的研究,发现在204.5nm、280.0nm两处有吸收峰.     

互联网时代的“数字化校园”建设与高校管理工作的思考

随着互联网的飞速发展,教育界掀起了一股数字化校园建设热潮,众多的学校纷纷投入到其中,架构在网络环境上的＂数字化校园＂成为学校信息化建设的重点。搞好校园网络建设,构建现代化的教育环境,成为教育现代化的重要内容,也是形成现代教育办学体系的重要组成部分。我们的数字化校园建设是要以网络技术、多媒体技术等现代化信息技术为手段、以提高教育教学工作效率为目的,实现资源的有效整合和优化,从根本上转变教育教学和管理模式与方法。因此,我们要从根本上转变思想,建立与完善现代化管理意识的校园网络;同时,加强师资队伍建设,培养一支素养高、勇于创新、善于运用现代化技术的教师队伍。     

西部地方高校《财务管理学》教学满意度调查研究

《财务管理学》是会计学专业重要的基础课和专业课程,课程的教学质量会直接影响到学生对后续课程的学习以及学生综合能力的培养。通过对财务管理学课程教学满意度进行调研,并应用因子分析的方法,期望得到相关的反馈信息。     

Discussion of the Hospital Union Management System Innovation in the New Era

医院工会作为工作人员利益的代表,在医院对工作人员开展的管理工作中发挥着极其重要的作用,而随着目前人力资源管理工作不断地趋于复杂,工会工作也产生了诸多新的工作任务.推动工会管理工作制度的有效创新,以使工会工作能够达到对时代要求的有效满足,已成为当前时期医院工作所不可避免的一项任务.文章通过分析新时期时代对于我国医院工会管理工作提出的新要求,探讨了医院积极对工会管理制度进行创新改革的几点措施.     

Preface

In the past decades, the ability of observing and manipulating quantum phenomena has been tremendously improved. It has advanced the thriving of quantum technologies with atomic, optical and solid-state systems.     

基于网络药理学研究厚朴-杏仁治疗哮喘的潜在作用机制

本研究采用网络药理学方法分析厚朴-杏仁配伍治疗哮喘的潜在作用机制。通过BATMAN-TCM数据库检索厚朴、杏仁的中药化学成分及靶标信息，PALM-IST数据库搜索疾病靶标信息，string数据库构建靶标的蛋白质相互作用网络，利用Cytoscape v3.5.1对药物靶标相互作用进行可视化分析，DAVID数据库和Cytoscape v3.5.1的ClueGO+CluePedia插件对药物关键靶标进行GO生物功能富集分析和KEGG信号通路富集分析。共检索到厚朴-杏仁化合物51个，靶标435个，哮喘疾病相关靶标415个，进而分析得到药物治疗疾病关键靶标14个，包括肿瘤坏死因子、过氧化氢酶、白介素13、β2肾上腺素能受体等；GO基因功能分析主要涉及应激反应调控、先天性免疫反应调控、防御反应、急性炎症反应、刺激反应、凝血止血调节、自我内稳定、活性氧代谢过程等生物过程；KEGG分析主要参与NF-κB、IL-17、FcεRI、Toll受体及FoxO等信号通路。厚朴-杏仁能通过多个靶点、多种途径、多条通路对哮喘的气道慢性炎症、气道重塑和气道高反应起潜在治疗作用。     

网络文化对当代青年政治认知的负面影响及对策

当代青年的政治认知即当代青年对政治客体即政治体制、政治权力、政治规范、政治功能等方面的认识、评价和判断。随着现代信息技术的高速发展,特别是因特网的日益普及,诞生了独特的网络文化。网络文化在推动当代青年政治认知发展的同时,也带来了不可低估的负面影响。积极采取有效措施,应对网络文化给青年的政治认知带来的负面影响,这不仅有利于当代青年的健康成长,而且也有利于我国社会的政治稳定。     

Sedimentation processes and sedimentary characteristics of tidal bores along the north bank of the Qiantang Estuary

A tidal bore is a unique Earth surface process, characterized by its highly destructive energy, predictable periodicities and magni-tudes, and the production of characteristic sedimentary features. Tidal bores and associated rapid flood flows are highly turbulent flows of the upper-flow regime with a velocity over several meters per second. Reynolds (Re) and Froude (Fr) numbers, respectively, are larger than 104 and 1.0, making them significantly different from regular tidal flows but analogous to turbidity currents. Until now, understanding of tidal-bore depositional processes and products has been limited because of the difficulty and hazards involved with gauging tidal bores directly. The Qiantang bore is known as the largest breaking bore in the world. Field surveys were carried out in May 2010, along the north bank of the Qiantang Estuary to observe the occurrence of peak bores, including regular observations of current, water level and turbidity at the main channel. Several short cores were sampled on the intertidal flats to study the characteristic sedimentary features of tidal bores. Hydrodynamic and sedimentological studies show that the processes of sediment resuspension, transport and deposition are controlled primarily by the tidal bores, and the subsequent abruptly accelerated and decelerated flood flows, which only account for one tenth of each semidiurnal tidal cycle in the estuary. Tidal-bore deposits are generally poorly sorted because of rapid sedimentation after highly mixed suspension by intense turbulence. This behavior is characteristic of the absence of tractive-current depositional components in a C-M diagram. It also goes along with well-developed massive bedding, graded bedding, basal erosion structures, convolute bedding and dewatering structures. Together, these sedimentary features can constitute fingerprinting of turbidites, widely distributed in the deep-water environment. However, a tidal bore is triggered by intensely deformed tidal waves propagating into a shallow-water environment, which returns to regular tidal flows rapidly after the passage of the bore head. The tidal-bore deposits are usually bounded by the intertidal-flat deposits with typical tidal beddings at the top and on both flanks. The difference between tidal-bore deposits (TBD) and tidal sandy/muddy deposits (TSD/TMD) is evident not only in sedimentary structures, but also in the grain-size composition. They can be clearly distinguished in grain-size bivariate plots, typically the plot of mean grain size vs. standard deviation (or sorting). Some trend variations generally exist in mean grain size with TBD>TSD>TMD, sorting with TMD>TBD>TSD (larger value indicating poorer sorting), and both skewness and kurtosis with TSD>TBD>TMD. These findings will undoubtedly shed new light on our understanding of tidal-bore sedimentology, ancient tidal-bore sedimentary facies and environments, and related oil-and-gas field prospecting.     

提高企业自主创新能力的对策

到目前为止,中国企业的自主创新能力较差,国际核心竞争力相对较弱,在激烈的市场竞争环境中,自主创新能力对我国企业的发展有着非常重要的意义,而且自主创新能力是国家竞争力的核心,创新型企业是我国建设创新型国家的基础,所以我国企业必须迅速提高企业的自主创新能力.     

岩溶地区桥梁桩基施工方法

通过某特大桥钻孔桩施工,介绍溶洞地区桥梁桩基施工常出现的问题、施工工艺、质量检测和预防处理措施.