钢管弧形切割机的设计

采用可在轨道上移动的加长电机轴的金属切割机来切割钢管端面,在钢管端面上加工出所需要的弧形,设计了钢管弧形切割机.该设计针对解决在管口现场的钢管弧形切割问题,与现有设备比较,具有加工范围广、精度高、机动性强的优点.     

Maize HapMap2 identifies extant variation from a genome in flux

Whereas breeders have exploited diversity in maize for yield improvements, there has been limited progress in using beneficial alleles in undomesticated varieties. Characterizing standing variation in this complex genome has been challenging, with only a small fraction of it described to date. Using a population genetics scoring model, we identified 55 million SNPs in 103 lines across pre-domestication and domesticated Zea mays varieties, including a representative from the sister genus Tripsacum. We find that structural variations are pervasive in the Z. mays genome and are enriched at loci associated with important traits. By investigating the drivers of genome size variation, we find that the larger Tripsacum genome can be explained by transposable element abundance rather than an allopolyploid origin. In contrast, intraspecies genome size variation seems to be controlled by chromosomal knob content. There is tremendous overlap in key gene content in maize and Tripsacum, suggesting that adaptations from Tripsacum (for example, perennialism and frost and drought tolerance) can likely be integrated into maize.     

A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis

To identify susceptibility loci for ankylosing spondylitis, we performed a two-stage genome-wide association study in Han Chinese. In the discovery stage, we analyzed 1,356,350 autosomal SNPs in 1,837 individuals with ankylosing spondylitis and 4,231 controls; in the validation stage, we analyzed 30 suggestive SNPs in an additional 2,100 affected individuals and 3,496 controls. We identified two new susceptibility loci between EDIL3 and HAPLN1 at 5q14.3 (rs4552569; P = 8.77 × 10(-10)) and within ANO6 at 12q12 (rs17095830; P = 1.63 × 10(-8)). We also confirmed previously reported associations in Europeans within the major histocompatibility complex (MHC) region (top SNP, rs13202464; P < 5 × 10(-324)) and at 2p15 (rs10865331; P = 1.98 × 10(-8)). We show that rs13202464 within the MHC region mainly represents the risk effect of HLA-B*27 variants (including HLA-B*2704, HLA-B*2705 and HLA-B*2715) in Chinese. The two newly discovered loci implicate genes related to bone formation and cartilage development, suggesting their potential involvement in the etiology of ankylosing spondylitis.     

碳氮比对A/O-MBR工艺中污水脱氮除磷的影响研究

在高、低碳氮比情况下,探究A/O-MBR现场工艺中污水氨氮、总氮和总磷的去除效率及其变化规律。研究结果显示,随着进水碳氮比升高,出水中总氮去除效率由(44.1±8.9)%提升至(78.5±7.9)%,总磷去除效率未受影响。差异性代谢产物分析表明,提升碳氮比能够增强菌群的氨基酸代谢功能,同时促进核黄素的生物合成,共同提升污水中氮的去除效率。     

用siRNA抑制胃癌细胞AGS中COX-2表达及对AKT磷酸化的抑制

构建了可在真核细胞中表达针对COX-2基因的siRNA表达载体,并用胃腺癌细胞系AGS建立了COX-2 siRNA的稳定转染细胞系。用Western-Blot检测稳定转染细胞系中COX-2的表达以及AKT的磷酸化水平。结果表明稳定转染C0X-2 siRNA的细胞中COX-2的表达较转染空载体的细胞明显降低,且发现COX-2表达的降低可抑制AKT—Ser^473和Thr-^308的磷酸化水平。为进-步探索抑制COX-2对胃癌细胞生物学特性的影响,及其在肿瘤治疗中的作用奠定了基础。     

柔软的黑人性与坚硬的主体性--解读《白宫管家》

《白宫管家》以交叉叙事的方式书写了西塞尔·盖恩斯在种族主义语境中的摇摆人生，以及与之相随的柔软黑人性和坚硬主体性，具体表现在三个方面：第一，棉花田里的舞勺之年，未谙世事的西塞尔以反抗彰显着其黑人性；第二，私刑下的而立与不惑，失去父亲的西塞尔用忍耐守望着自己的主体性，尽量不谈政治；第三，后政治秀的耄耋期颐，失去儿子的西塞尔凭反抗坚守着长期以来其族裔所需的黑人性。实际上，这三段从反抗→忍耐→反抗的人生，是当时黑人在“主人”宰制下的策略生存，旨在以迎合语境所允许个体“奴仆”承载的主体性的前提下守护集体的黑人性。     

高强贝氏体钢测定R_(P0.2)准确性分析

对高强贝氏体钢在拉伸检测过程中影响测定RP0.2准确性的检测方法、检测设备和检测材料三个因素进行了分析。通过严格控制检测材料加工的平行度和加工面的平整度,及时更换磨损过度的钳口套和钳口并保证充分润滑,有效的解决了力学拉伸曲线紊乱,不能准确测定高强贝氏体钢非比例延伸强度RP0.2的问题。     

具阻尼和动态边界的热弹性板的指数衰减性

文章研究一个具有阻尼和动态边界条件的热弹性板的指数衰减性,运用频域方法和偏微分方程的技巧证明了所考虑弹性系统的能量是指数衰减的.     

千禧·龙城住宅小区规划设计

从开发优势条件、规划范围、规划原则、规划理念等方面阐述了千禧·龙城住宅小区的具体规划设计。     

右中立Beta过程的一些结果

给出了非参数Bayesian 中的Beta 过程的2个性质,并证明了在考虑非参数Bayesian 时,用Beta 过程和Beta-Stacy 过程作先验是等价的.