双湖记

长期以来,俄国都拥有着本文将着力研究的两个湖的主权:西伯利亚的贝加尔湖和南极的罗斯托克湖。它们都有着诱人的秘密:关于气候的变化、物种的进化、生物怎样在极端恶劣的环境下生存,也许还有关于其他星球上的生命。     

教学产品是怎样形成的

1在木桶里寻求答案当然．对教师来说．“产品”一词还不能象“教学结果”概念那样被普通使用。在使用这个词的时候．往往是每次不得不作准确说明．即在每一具体场合，所指的是怎样一种结果。不知是指可以用肉眼看得到的知识、技能、能力．还是指深刻的潜在的新生物——个人的思维水平和类型．世界观和视野、兴趣和认识的需要、工作厅式、积极性．热爱劳动及为教学所形成的其它各种品质。要想对不确定的结果作系统分析是件困难的事·然而对4一切创造过程来说“产品”和“产品率”的一般概念可以使思想、体系和结构更加清晰。它们开辟了由教学…     

时变系统的稳定性

§1 引言文献[1—3]都对变系数线性系统的稳定性进行了研究,特别在文[3]中利用Ляпунов函数法对缓变系数系统稳定性的研究,得到较好的结果,我们于本文中借助于文[3]的思想,讨论了一般变系数线性系统的稳定性,得到一些结果,改进和推广了这方面的研究。     

Regulation of cellulose synthesis in Acetobacter xylinum by cyclic diguanylic acid

Cellulose is the most abundant renewable carbon resource on earth and is an indispensable raw material for the wood, paper, and textile industries. A model system to study the mechanism of cellulose biogenesis is the bacterium Acetobacter xylinum which produces pure cellulose as an extracellular product. It was from this organism that in vitro preparations which possessed high levels of cellulose synthase activity were first obtained in both membranous and soluble forms. We recently demonstrated that this activity is subject to a complex multi-component regulatory system, in which the synthase is directly affected by an unusual cyclic nucleotide activator enzymatically formed from GTP, and indirectly by a Ca (2+) -sensitive phosphodiesterase which degrades the activator. The cellulose synthase activator (CSA) has now been identified as bis-(3' 5')-cyclic diguanylic acid (5'G3'p5'G3'p) on the basis of mass spectroscopic data, nuclear magnetic resonance analysis and comparison with chemically synthesized material. We also report here on intermediary steps in the synthesis and degradation of this novel circular dinucleotide, which have been integrated into a model for the regulation of cellulose synthesis.