Optimal design and experiment research of an orthogonal-parallel six-axis force/torque sensor

A novel orthogonal-parallel six-axis force/torque sensor is studied based on a modified Stewart platform architecture,and the optimal design and experiment rese...     

SAm级防撞活动护栏碰撞仿真分析

针对目前高速公路中央分隔带开口处活动护栏防撞等级较低的问题,提出了一种SAm级混凝土活动护栏及一种新型连接装置.基于有限元的方法,建立车辆与护栏的碰撞模型,通过LS-DYNA对车辆与护栏碰撞过程进行求解,根据不同车型的碰撞结果分别在缓冲,阻挡和导向性能上对护栏的安全性能进行评价,其中小型车辆与护栏碰撞后的OIV(Occ...     

三种咪唑物质检测技术研究进展

咪唑、2-甲基咪唑及4-甲基咪唑是一类五元杂环小分子化合物,2-甲基咪唑和4-甲基咪唑是同分异构体,常是氨(铵)法生产食品添加剂—焦糖色素的副反应产物,是影响食品添加剂安全性的重要因素.其中4-甲基咪唑会抑制细胞色素P450同功酶,引起人体畸变、癌变等症状,危害人体健康.近年来,有文献先后报道了咪唑及(2-或4-)甲基...     

感光树脂版伪造印章印文的检验

感光树脂制版伪造印章与真实印章的印章规格特征基本相同;伪造后的印章印文在笔画的细节形态、长短、角度、起收笔部位,以及细小笔画的相互搭配关系等方面会与真实印章印文表现出一定的差异;在制作伪印章时,由于犯罪分子疏漏导致的个别背景纹线残留在底片上,或者修版过度造成印迹缺损等现象,都会在伪章盖印的印文中反映出来。在检验时,应结合照相制版及感光树脂材料的特性进行具体分析和综合评断。     

Experimental studies on oxidizing removal of Cyclops of zooplankton

0 IntroductionCyclops couldn’t be effectively inactivated by theconventional disinfection such as chlorination due to itsstronger resistance to oxidation.In addition,the motilityof Cyclops makes it easily penetrate sand filter into theclean water tank in waterworks , even municipal servicepipe .Adult Cyclops , with body length of one to severalmillimeters, may be caught by naked eye to bring con-sumers unsanitary sense and may become disease trans-mission mediumas the host of pathogenic para…     

Yersinia pestis genome sequencing identifies patterns of global phylogenetic diversity

Plague is a pandemic human invasive disease caused by the bacterial agent Yersinia pestis. We here report a comparison of 17 whole genomes of Y. pestis isolates from global sources. We also screened a global collection of 286 Y. pestis isolates for 933 SNPs using Sequenom MassArray SNP typing. We conducted phylogenetic analyses on this sequence variation dataset, assigned isolates to populations based on maximum parsimony and, from these results, made inferences regarding historical transmission routes. Our phylogenetic analysis suggests that Y. pestis evolved in or near China and spread through multiple radiations to Europe, South America, Africa and Southeast Asia, leading to country-specific lineages that can be traced by lineage-specific SNPs. All 626 current isolates from the United States reflect one radiation, and 82 isolates from Madagascar represent a second radiation. Subsequent local microevolution of Y. pestis is marked by sequential, geographically specific SNPs.     

Molecular mechanisms of BK channel activation

Large conductance, Ca²⁺-activated potassium (BK) channels are widely expressed throughout the animal kingdom and play important roles in many physiological processes, such as muscle contraction, neural transmission and hearing. These physiological roles derive from the ability of BK channels to be synergistically activated by membrane voltage, intracellular Ca²⁺ and other ligands. Similar to voltage-gated K⁺ channels, BK channels possess a pore-gate domain (S5–S6 transmembrane segments) and a voltage-sensor domain (S1–S4). In addition, BK channels contain a large cytoplasmic C-terminal domain that serves as the primary ligand sensor. The voltage sensor and the ligand sensor allosterically control K⁺ flux through the pore-gate domain in response to various stimuli, thereby linking cellular metabolism and membrane excitability. This review summarizes the current understanding of these structural domains and their mutual interactions in voltage-, Ca²⁺ - and Mg²⁺ -dependent activation of the channel. Received 25 September 2008; received after revision 23 October 2008; accepted 24 October 2008     

技术转移协商谈判系统方法探讨

技术转移谈判一直困扰着参与技术转移的双方,针对这一问题本文借鉴并发展了现有的协商谈判方法,提出了适用于技术转移的协商谈判的系统方法,以引导双方在谈判中达到“共同盈得”的协议．     

流行词“吃货”的多角度考察

"吃货"最早出现在清代小说中,指光吃不干活的人,带有贬义色彩。近年来,"吃货"一词被广大美食爱好者广泛传播,用于自称和互称。"吃货"一词的词义已发生明显变化,指"喜欢吃各类美食的人,有品位的美食爱好者";词义附带的感情色彩逐渐趋于中性甚至褒义。而导致这些变化的原因主要是人们对"吃"观念的改变,网络语言环境的高度自由化以及使用网络语言的从众心理。     

综合环境费用的概念与计算方法研究

在分析了环境费用的概念及估价方法后 ,针对环境费用较难以估量的问题 ,提出了综合环境费用的概念 ,并在投入占用产出的框架内 ,给出了三种计算方法 .在综合环境费用的基础上 ,给出了衡量环境破坏程度的相对指标 -环境破坏度的概念 ,并对其计算方法进行了研究 .