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排序方式: 共有67条查询结果,搜索用时 15 毫秒
31.
Fabian AC Johnstone RM Sanders JS Conselice CJ Crawford CS Gallagher JS Zweibel E 《Nature》2008,454(7207):968-970
The giant elliptical galaxy NGC 1275, at the centre of the Perseus cluster, is surrounded by a well-known giant nebulosity of emission-line filaments, which are plausibly in excess of 10(8) years old. The filaments are dragged out from the centre of the galaxy by radio-emitting 'bubbles' rising buoyantly in the hot intracluster gas, before later falling back. They act as markers of the feedback process by which energy is transferred from the central massive black hole to the surrounding gas. The mechanism by which the filaments are stabilized against tidal shear and dissipation into the surrounding extremely hot (4 x 10(7) K) gas has been unclear. Here we report observations that resolve thread-like structures in the filaments. Some threads extend over 6 kpc, yet are only 70 pc wide. We conclude that magnetic fields in the threads, in pressure balance with the surrounding gas, stabilize the filaments, so allowing a large mass of cold gas to accumulate and delay star formation. 相似文献
32.
Individual variation in gene expression is important for evolutionary adaptation and susceptibility to diseases and pathologies. In this study, we address the functional importance of this variation by comparing cardiac metabolism to patterns of mRNA expression using microarrays. There is extensive variation in both cardiac metabolism and the expression of metabolic genes among individuals of the teleost fish Fundulus heteroclitus from natural outbred populations raised in a common environment: metabolism differed among individuals by a factor of more than 2, and expression levels of 94% of genes were significantly different (P < 0.01) between individuals in a population. This unexpectedly high variation in metabolic gene expression explains much of the variation in metabolism, suggesting that it is biologically relevant. The patterns of gene expression that are most important in explaining cardiac metabolism differ between groups of individuals. Apparently, the variation in metabolism seems to be related to different patterns of gene expression in the different groups of individuals. The magnitude of differences in gene expression in these groups is not important; large changes in expression have no greater predictive value than small changes. These data suggest that variation in physiological performance is related to the subtle variation in gene expression and that this relationship differs among individuals. 相似文献
33.
Crawford N. Sutton Maureen Horsfield G. I. 《Cellular and molecular life sciences : CMLS》1966,22(11):710-710
Zusammenfassung Im Verlauf elektronenmikroskopischer Untersuchungen der Thrombocyten des Menschen wurden Fibrillen von etwa 200 å im Durchmesser beobachtet, die Bündel bilden, welche sich durch die ganze Zelle und in die cytoplasmatischen Fortsätze erstrecken können. Diese Struktur steht mit dem Vorhandensein eines kontraktilen Proteins im Zusammenhang. 相似文献
34.
Wild turkey ( Meleagris gallopavo ) brood-rearing sites have been described for portions of their range, but brood-rearing habitat use and characteristics of brood-rearing sites used by Rio Grande Wild Turkeys ( M. g. intermedia ) in the Pacific Northwest were unknown. We described cover types at 362 brood-rearing sites and measured habitat characteristics at 64 of these sites used by a recently established Rio Grande Wild Turkey population in southwestern Oregon during May-September 1989 and 1990. Hens with broods used 9 of 10 available cover types. Meadows, mixed hardwood/conifer woodlands, and savannas were used more often than expected (47% of observations, P ≤ 0.05). Broods used mature mixed conifer and dense sapling/pole mixed conifer cover types less than expected and did not use brush-fields. Many brood-rearing sites were characterized by a parklike appearance. Understory vegetation averaged P ≤ 0.05). We suggest that land managers maintain mixed hardwood/conifer woodland and savanna cover types adjacent to meadows on south slopes to provide brood-rearing habitat for Rio Grande Wild Turkeys in southwestern Oregon. 相似文献
35.
Neale BM Kou Y Liu L Ma'ayan A Samocha KE Sabo A Lin CF Stevens C Wang LS Makarov V Polak P Yoon S Maguire J Crawford EL Campbell NG Geller ET Valladares O Schafer C Liu H Zhao T Cai G Lihm J Dannenfelser R Jabado O Peralta Z Nagaswamy U Muzny D Reid JG Newsham I Wu Y Lewis L Han Y Voight BF Lim E Rossin E Kirby A Flannick J Fromer M Shakir K Fennell T Garimella K Banks E Poplin R Gabriel S DePristo M Wimbish JR Boone BE Levy SE Betancur C Sunyaev S Boerwinkle E Buxbaum JD Cook EH Devlin B 《Nature》2012,485(7397):242-245
Autism spectrum disorders (ASD) are believed to have genetic and environmental origins, yet in only a modest fraction of individuals can specific causes be identified. To identify further genetic risk factors, here we assess the role of de novo mutations in ASD by sequencing the exomes of ASD cases and their parents (n = 175 trios). Fewer than half of the cases (46.3%) carry a missense or nonsense de novo variant, and the overall rate of mutation is only modestly higher than the expected rate. In contrast, the proteins encoded by genes that harboured de novo missense or nonsense mutations showed a higher degree of connectivity among themselves and to previous ASD genes as indexed by protein-protein interaction screens. The small increase in the rate of de novo events, when taken together with the protein interaction results, are consistent with an important but limited role for de novo point mutations in ASD, similar to that documented for de novo copy number variants. Genetic models incorporating these data indicate that most of the observed de novo events are unconnected to ASD; those that do confer risk are distributed across many genes and are incompletely penetrant (that is, not necessarily sufficient for disease). Our results support polygenic models in which spontaneous coding mutations in any of a large number of genes increases risk by 5- to 20-fold. Despite the challenge posed by such models, results from de novo events and a large parallel case-control study provide strong evidence in favour of CHD8 and KATNAL2 as genuine autism risk factors. 相似文献
36.
M McDonald M Bayliss BA Benson RJ Foley J Ruel P Sullivan S Veilleux KA Aird ML Ashby M Bautz G Bazin LE Bleem M Brodwin JE Carlstrom CL Chang HM Cho A Clocchiatti TM Crawford AT Crites T de Haan S Desai MA Dobbs JP Dudley E Egami WR Forman GP Garmire EM George MD Gladders AH Gonzalez NW Halverson NL Harrington FW High GP Holder WL Holzapfel S Hoover JD Hrubes C Jones M Joy R Keisler L Knox AT Lee EM Leitch J Liu M Lueker D Luong-Van A Mantz DP Marrone JJ McMahon J Mehl SS Meyer ED Miller 《Nature》2012,488(7411):349-352
In the cores of some clusters of galaxies the hot intracluster plasma is dense enough that it should cool radiatively in the cluster's lifetime, leading to continuous 'cooling flows' of gas sinking towards the cluster centre, yet no such cooling flow has been observed. The low observed star-formation rates and cool gas masses for these 'cool-core' clusters suggest that much of the cooling must be offset by feedback to prevent the formation of a runaway cooling flow. Here we report X-ray, optical and infrared observations of the galaxy cluster SPT-CLJ2344-4243 (ref. 11) at redshift z = 0.596. These observations reveal an exceptionally luminous (8.2?×?10(45)?erg?s(-1)) galaxy cluster that hosts an extremely strong cooling flow (around 3,820 solar masses a year). Further, the central galaxy in this cluster appears to be experiencing a massive starburst (formation of around 740 solar masses a year), which suggests that the feedback source responsible for preventing runaway cooling in nearby cool-core clusters may not yet be fully established in SPT-CLJ2344-4243. This large star-formation rate implies that a significant fraction of the stars in the central galaxy of this cluster may form through accretion of the intracluster medium, rather than (as is currently thought) assembling entirely via mergers. 相似文献
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39.
The study of patterns in living diversity is driven by the desire to find the universal rules that underlie the organization of ecosystems. The relative abundance distribution, which characterizes the total number and abundance of species in a community, is arguably the most fundamental measure in ecology. Considerable effort has been expended in striving for a general theory that can explain the form of the distribution. Despite this, a mechanistic understanding of the form in terms of physiological and environmental parameters remains elusive. Recently, it has been proposed that space plays a central role in generating the patterns of diversity. Here we show that an understanding of the observed form of the relative abundance distribution requires a consideration of how individuals pack in time. We present a framework for studying the dynamics of communities which generalizes the prevailing species-based approach to one based on individuals that are characterized by their physiological traits. The observed form of the abundance distribution and its dependence on richness and disturbance are reproduced, and can be understood in terms of the trade-off between time to reproduction and fecundity. 相似文献
40.
The motor side of depth vision 总被引:7,自引:0,他引:7
To achieve stereoscopic vision, the brain must search for corresponding image features on the two retinas. As long as the eyes stay still, corresponding features are confined to narrow bands called epipolar lines. But when the eyes change position, the epipolar lines migrate on the retinas. To find the matching features, the brain must either search different retinal bands depending on current eye position, or search retina-fixed zones that are large enough to cover all usual locations of the epipolar lines. Here we show, using a new type of stereogram in which the depth image vanishes at certain gaze elevations, that the search zones are retina-fixed. This being the case, motor control acquires a crucial function in depth vision: we show that the eyes twist about their lines of sight in a way that reduces the motion of the epipolar lines, allowing stereopsis to get by with smaller search zones and thereby lightening its computational load. 相似文献