空域色噪声背景下双基地MIMO雷达角度估计

空域有色噪声会导致现有多输入多输出(multiple input multiple output, MIMO)雷达算法性能下降, 甚至完全失效。针对空域色噪声背景下双基地MIMO雷达联合波离角(direction of departure, DOD)和波达角(direction of arrival, DOA)估计问题, 分析了现有算法失效的原因。考虑到匹配滤波后无噪协方差矩阵的低秩特性、色噪声协方差矩阵的稀疏特性以及MIMO雷达数据的多维结构特性, 提出一种基于张量分析的角度估计算法。首先, 构造角度估计的协方差张量, 通过去除协方差张量中受噪声协方差影响的元素对色噪声进行抑制。其次,利用张量填充技术对无噪协方差矩阵进行恢复。然后,利用平行因子分解获得目标角度的方向矩阵。最后, 采用最小二乘算法对目标的DOA和DOD进行拟合。仿真结果表明, 所提算法对色噪声不敏感, 且无孔径损失。相比现有矩阵及张量分析算法, 所提算法具有更高的估计精度。     

基于OSG林地可视化系统设计与实现

森林、树木和花卉等植被实时可视化仿真是复杂虚拟园林环境中的重要组成部分.论文基于OpensceneGraph(OSG)和实时建模工具MuitiGen Creator(Creator)设计并实现了林分场景可视化系统.重点介绍了系统实现的框架和技术流程,并对如何在Creator中建立模型的层次结构关系进行了分析与研究.同时对该系统中使用的关键技术,如粒子系统、漫游设计和碰撞检测等实现方法进行了介绍.最后利用该方法对北京市八达岭地区林分场景进行了可视化模拟,模拟的场景逼真、自然,能满足用户实时交互的需要.     

Common variants near MC4R are associated with fat mass, weight and risk of obesity

To identify common variants influencing body mass index (BMI), we analyzed genome-wide association data from 16,876 individuals of European descent. After previously reported variants in FTO, the strongest association signal (rs17782313, P = 2.9 x 10(-6)) mapped 188 kb downstream of MC4R (melanocortin-4 receptor), mutations of which are the leading cause of monogenic severe childhood-onset obesity. We confirmed the BMI association in 60,352 adults (per-allele effect = 0.05 Z-score units; P = 2.8 x 10(-15)) and 5,988 children aged 7-11 (0.13 Z-score units; P = 1.5 x 10(-8)). In case-control analyses (n = 10,583), the odds for severe childhood obesity reached 1.30 (P = 8.0 x 10(-11)). Furthermore, we observed overtransmission of the risk allele to obese offspring in 660 families (P (pedigree disequilibrium test average; PDT-avg) = 2.4 x 10(-4)). The SNP location and patterns of phenotypic associations are consistent with effects mediated through altered MC4R function. Our findings establish that common variants near MC4R influence fat mass, weight and obesity risk at the population level and reinforce the need for large-scale data integration to identify variants influencing continuous biomedical traits.     

Systematic assessment of copy number variant detection via genome-wide SNP genotyping

SNP genotyping has emerged as a technology to incorporate copy number variants (CNVs) into genetic analyses of human traits. However, the extent to which SNP platforms accurately capture CNVs remains unclear. Using independent, sequence-based CNV maps, we find that commonly used SNP platforms have limited or no probe coverage for a large fraction of CNVs. Despite this, in 9 samples we inferred 368 CNVs using Illumina SNP genotyping data and experimentally validated over two-thirds of these. We also developed a method (SNP-Conditional Mixture Modeling, SCIMM) to robustly genotype deletions using as few as two SNP probes. We find that HapMap SNPs are strongly correlated with 82% of common deletions, but the newest SNP platforms effectively tag about 50%. We conclude that currently available genome-wide SNP assays can capture CNVs accurately, but improvements in array designs, particularly in duplicated sequences, are necessary to facilitate more comprehensive analyses of genomic variation.     

张拉膜结构风振响应的数值风洞模拟

膜结构作为一种风敏感结构,其风致振动需考虑流固耦合效应.建立膜结构风振响应的数值模拟平台,该平台调用已有的结构计算模块ANSYS以及流场求解模块CFX,并开发了大位移边界下的动态网格更新以及流固耦合边界的自匹配功能,从而实现了膜结构风振响应的数值模拟计算.利用该平台对工程应用较为广泛的典型张拉膜结构进行了初步风致振动响应研究.数值模拟结果显示:张拉膜结构的风振是由结构多个模态的耦合叠加所组成,其风振响应体现了结构较强的几何非线性特征;来流的风速大小、风向角以及张拉膜的预张力、矢跨比等因素都会对结构的风振响应产生一定的影响.     

病毒基因组中的对称性

病毒基因组中的重复序列比率很低,因为其核酸序列大都是编码区域.如果出现一段同向对称或者是反向对称序列在病毒基因组中,它往往代表一个调控元件,或者是一个信号因子.我们总结了病毒中的一些对称序列,并阐明它的特点,分布及功能.     

我国优秀棒球运动员推理能力特征的研究

采用实验与统计相结合的方法,对我国优秀棒球运动员推理能力特征进行了研究。结果表明:不同训练年限的棒球运动员在推理能力测验上存在的差异显著;高运动等级的运动员的推理能力优于低运动等级的运动员;投手在对系统变化的认识能力上较其他防守位置的队员得到了良好的发展。     

一种基于MPXY8020A的智能胎压监测系统设计

概述了当前汽车智能胎压监测系统(TPMS)的发展现状,并介绍了基于Motorola公司智能传感器MPXY8020A的智能胎压监测系统设计开发过程。该系统分为压力采集、发射和压力接收、显示两个子系统,在介绍了整个系统的系统结构后,分别对硬件和软件的设计与实现进行了描述。