Lung cancer susceptibility locus at 5p15.33

We carried out a genome-wide association study of lung cancer (3,259 cases and 4,159 controls), followed by replication in 2,899 cases and 5,573 controls. Two uncorrelated disease markers at 5p15.33, rs402710 and rs2736100 were detected by the genome-wide data (P = 2 x 10(-7) and P = 4 x 10(-6)) and replicated by the independent study series (P = 7 x 10(-5) and P = 0.016). The susceptibility region contains two genes, TERT and CLPTM1L, suggesting that one or both may have a role in lung cancer etiology.     

一种新型2.45GHz准椭圆LTCC低通滤波器

设计了一种新型2.45GHz含螺旋传输线结构的准椭圆LTCC低通滤波器,给出了带外传输有限零点的解析公式.针对实际结构中的螺旋传输线的寄生耦合效应,修正了该滤波器的等效电路,使仿真等效电路得到的散射参数曲线与测量结果相互吻合.测量结果表明,该低通滤波器性能良好,达到了指标要求.     

烟道式锅炉飞灰微波测碳系统的开发和应用

该文基于国内外现有微波测碳方法存在的问题,提出了一种新的烟道式微波测碳系统的工作原理,设计特点及试验结果,这种新方法不需附加采样装置,故结构荼量小,可实时连续监测飞灰含碳量。     

中菊头蝠和折翼蝠组织乳酸脱氢酶同工酶的研究

以聚丙烯酰胺凝胶电泳法,测定了中菊头蝠（Ｒｈｉｎｏｌｏｐｈｕｓａｆｆｉｎｉｓ）和折翼蝠（Ｍｉｎｉｏｐｔｅｒｕｓｓｃｈｒｅｉｂｅｒｓｉ）的心脏、肝、胃、肾脏、骨骼肌和脑等６种组织乳酸脱氢酶（ｌａｃｔａｔｅｄｅｈｙｄｒｏｇｅｎａｓｅ,ＬＤＨ）同工酶．结果显示：①ＬＤＨ同工酶在不同动物的不同组织中表达各异;②出现了骨骼肌中Ｂ亚基含量显著高于Ａ亚基的异常现象,可能与翼手类飞行时需大量能量来源的生理特性有关     

基于BERT的数控机床故障领域命名实体识别

针对数控机床(computer numerical control,CNC)故障领域命名实体识别方法中存在实体规范不足及有效实体识别模型缺乏等问题,制定了领域内实体标注策略,提出了一种基于双向转换编码器(bidirectional encoder representations from transformers,BERT)的数控机床故障领域命名实体识别方法。采用BERT编码层预训练,将生成向量输入到双向长短期记忆网络(bidirectional long short-term memory,BiLSTM)交互层以提取上下文特征,最终通过条件随机域(conditional random field,CRF)推理层输出预测标签。实验结果表明,BERT-BiLSTM-CRF模型在数控机床故障领域更具优势,与现有模型相比,F1值提升大于1.85%。     

沸石的复合改性及其同步脱氮除磷效果

为了解决污水处理厂后续脱氮除磷处理工艺的占地及成本问题,以廉价天然沸石为原料,制备了能够同步脱氮除磷的复合改性沸石,研究了不同制备条件对吸附效果的影响.研究结果表明,季铵盐-氯化钠复合改性沸石不仅去除氨氮,而且实现了同步去除磷和硝氮,脱氮除磷速度快,效率高,且去除互不影响;对氨氮、磷和硝氮的吸附数据均符合伪二级动力学方程.当该沸石在生活污水中的投加量为50 g/L时,实际出水水质可由一级B一步提高到一级A,对氨氮、硝氮和磷的去除率分别高达71.09%,91.18%,93.11%.吸附饱和后的沸石经单一的NaCl溶液再生后可循环使用,且再生时间短,操作简单.该复合改性沸石在实际生活污水的处理中具有良好的应用前景.     

降雨影响下紧邻桥梁软土基坑围护结构受力变形研究

某基坑受连续降雨影响,基坑围护结构及其紧邻桥梁桩基受力变形影响较大,施工安全风险大增。为此,本文基于饱和与非饱和土体强度参数变化规律和线性内插法对坑内土体力学参数进行计算,结合现场实测数据,采用有限元模拟分析了坑内降水及开挖所引起的围护结构受力变形规律及紧邻桥梁桩基变形规律,并探讨了降雨时长对基坑围护结构变形影响。结果表明,基坑开挖至坑底,围护结构发生“踢脚”大变形,易引起第一道混凝土支撑受拉脱落,最大水平位移发生在围护结构底部;桥梁桩基减弱了因开挖引起的基坑周围土体滑移,造成围护结构两侧受力不对称,导致其远离桩基侧变形过大;降雨引起坑内部分土体软化,使得围护结构水平位移进一步增大;在基坑非饱和区范围内且降雨强度一定时,围护结构水平位移量随降雨时长呈非线性加速增长趋势。     

Evaluating Volume Fractions of the Elements for Composite Laminates by Using Dielectric Properties

A series and parallel model for investigating the capacity of composite laminates and the relationship between the dielectric properties of the composites and its constituents are presented. Volume fractions of the constituents are considered in this study. The expression of the complex dielectric constants for evaluating volume fractions under discrete frequencies is established and the general solutions for the resultant linear simultaneous equations for system are also exploited. The results show that the high accuracy of proposed method is obtained.     

Statistical analyses of metric data of hominoid teeth found in Yuanmou of China

Mesial-distal and buccal-lingual dimensions of 1 266 hominoid teeth found in Yuanmou of Yunnan Province during the period of 1986 and 1988 have been measured. The statistical analyses of the metric data show that the tooth sizes of Yuanmou hominoid can be divided into big and small two types, and most tooth dimensions display obvious bimodalities in both histograms and 2 dimensional plots. The coefficients of variance (CV) reveal that the CVs of Yuanmou hominoid tooth sizes are within or close to the CV ranges ofLufengpithecus and extant great apes. The comparisons of tooth sizes and their proportions indicate that Yuanmou hominoids have close affinities with Lefeng and Kaiyuan hominoids, and have obvious differences with Gorilla, Chimpanzee and Orangutan. The authors believe that the hominoid fossils found in Yuanmou in the past 10 years represent a single species with highly sexual dimorphism in morphology and this species may have a close evolutionary relationship with the hominoids found in Kaiyuan and Lufeng.     

Periodicity of Holocene climatic variations in the Huguangyan Maar Lake

There exist five primary periods of 2 930, 1 140, 490, 250 and 220 a in the Holocene climatic variations in the Huguangyan Maar Lake, according to the energy-spectrum and filter analyses of high-resolution time sequences (10–15 a) of the sediment dry density. The peak values of the three temperature-decreasing periods with the 2 930 a cycle occur at about 7 300, 4 250 and 1 200 Cal. aBP. There are 7–8 temperature-decreasing periods with the 1 140 a cycle, and the climate fluctuation range is largest in the early Holocene, and reduces gradually in the middle and late Holocene. The millennial-scale climatic change in the Holocene may adjust the global water cycle and the thermohaline circulation intensity through the harmonic tones of the earth’s precession cycle, which in turn influences the global climate change.