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951.
A. Chung S. Y. Kim L. T. Cheng A. Castro Ph. D. 《Cellular and molecular life sciences : CMLS》1973,29(7):820-821
Résumé On a développé un anticorps d'une grande affinité et spécifité envers le phénobarbital en inoculant des lapins avec une solution de barbiturateprotéide, synthétisée d'acide barbiturique de 5-phényl-5-(4-aminobutyl) et d'albumine de sérum bovin par du carbodiimide. Usant de cet anticorps comme radioimmunoeassai, on peut mesurer jusqu'à 1 picomole de phénobarbital par ml de fluides biologique sans que d'autres barbiturates y opposent une réaction significative.
We express our appreciation to the Lilly Research Laboratories for the donation of amobarbital and secobarbital. 相似文献
We express our appreciation to the Lilly Research Laboratories for the donation of amobarbital and secobarbital. 相似文献
952.
953.
The recent discovery of a pterosaur egg with embryonic skeleton and soft tissues from the Yixian Formation confirmed that the flying pterosaurs were oviparous. Here we describe another pterosaur egg whose exquisite preservation indicates that the shell structure was soft and leathery. 相似文献
954.
Each cone photoreceptor in the retina responds to light in a limited range of wavelengths, giving it a spectral phenotype. This phenotype is determined by the most prevalent of the photoreceptor's visual-pigment proteins (opsins) and is assumed to remain unchanged during an animal's lifetime. Here we show that in the Pacific pink salmon, Oncorhynchus gorbuscha, single cones can switch their spectral phenotype from ultraviolet to blue by regulating the production of the appropriate opsins as the fish grow older. This photoreceptor plasticity may operate to modulate colour vision as the salmon's lifestyle changes. 相似文献
955.
Novel aspects of glypican glycobiology 总被引:5,自引:0,他引:5
Fransson LA Belting M Cheng F Jönsson M Mani K Sandgren S 《Cellular and molecular life sciences : CMLS》2004,61(9):1016-1024
Mutations in glypican genes cause dysmorphic and overgrowth syndromes in men and mice, abnormal development in flies and worms, and defective gastrulation in zebrafish and ascidians. All glypican core proteins share a characteristic pattern of 14 conserved cysteine residues. Upstream from the C-terminal membrane anchorage are 3–4 heparan sulfate attachment sites. Cysteines in glypican-1 can become nitrosylated by nitric oxide in a copper-dependent reaction. When glypican-1 is exposed to ascorbate, nitric oxide is released and participates in deaminative cleavage of heparan sulfate at sites where the glucosamines have a free amino group. This process takes place while glypican-1 recycles via a nonclassical, caveolin-1-associated route. Glypicans are involved in growth factor signalling and transport, e.g. of polyamines. Cargo can be unloaded from heparan sulfate by nitric oxide-dependent degradation. How glypican and its degradation products and the cargo exit from the recycling route is an enigma.Received 27 November 2003; received after revision 8 January 2004; accepted 13 January 2004 相似文献
956.
Wet periods in northeastern Brazil over the past 210 kyr linked to distant climate anomalies 总被引:1,自引:0,他引:1
Wang X Auler AS Edwards RL Cheng H Cristalli PS Smart PL Richards DA Shen CC 《Nature》2004,432(7018):740-743
The tropics are the main source of the atmosphere's sensible and latent heat, and water vapour, and are therefore important for reconstructions of past climate. But long, accurately dated records of southern tropical palaeoclimate, which would allow the establishment of climatic connections to distant regions, have not been available. Here we present a 210,000-year (210-kyr) record of wet periods in tropical northeastern Brazil--a region that is currently semi-arid. The record is obtained from speleothems and travertine deposits that are accurately dated using the U/Th method. We find wet periods that are synchronous with periods of weak East Asian summer monsoons, cold periods in Greenland, Heinrich events in the North Atlantic and periods of decreased river runoff to the Cariaco basin. We infer that the wet periods may be explained with a southward displacement of the Intertropical Convergence Zone. This widespread synchroneity of climate anomalies suggests a relatively rapid global reorganization of the ocean-atmosphere system. We conclude that the wet periods probably affected rainforest distribution, as plant fossils show that forest expansion occurred during these intermittent wet intervals, and opened a forest corridor between the Amazonian and Atlantic rainforests. 相似文献
957.
从马克思主义哲学和伦理学的视角论证了“三个代表”的内在辩证关系及伟大意义,指出高校思想政治工作必须按照“三个代表”的要求,加大思想政治工作的科技含量,加强思想政治工作的体制创新,思政工作的创新关键是以人为本,重在实践。 相似文献
958.
This paper deals with the experimental study on the correlation between the geometrical parameters of electrical tree and corresponding partial discharge (PD) characteristic parameters in the course of electrical tree aging within cross linked polyethylene (XLPE) insulation. The electrical tree aging tests were performed on specimens removed from a section of 220 kV transmission cable. The PD macroscopic characteristic parameters were found to be significantly dependent on the corresponding geometrical parameters of electrical tree channels in the course of aging of XLPE, and different kind of electrical tree has different characteristics, and there is obvious correlation between the type of electrical tree and the pre-applied power-frequency stress. Beside, using regression analysis, the expression of the relation between them were obtained, and from which it can be seen that there is significant nonlinear correlation between geometrical parameters of electrical tree and corresponding PD characteristic parameters in the course of aging of XLPE. Therefore, the aging degree of XLPE can be effectively evaluated by recognizing the changing regularity of the PD rnacroscopic characteristic parameters. 相似文献
959.
In this work, we made progress on the problem that [ symbol: see text] is a Banach algebra under schur product. Our results extend Tonge's results. We also obtained estimates for the norm of the random quadralinear form A:l(r)(M) x l(p)(N) x l(q)(K) x l(s)(H)-->C, defined by: A(e(i), e(j), e(k), e(s))=a(ijks), where the (a(ijks))'s are uniformly bounded, independent, mean zero random variables. We proved that under some conditions [ symbol: see text] is not a Banach algebra under schur product. 相似文献
960.
The new Moderate-Resolution Imaging Spectroradiometer (MODIS) satellite image offers a large choice of opportunities for operational applications. The 1-km Advanced Very High Resolution Radiometer (AVHRR) image is not suitable for retrieval of field level parameter and Landsat data are not frequent enough for monitoring changes in crop parameters during the critical crop growth periods.A methodology to map areas of paddy fields using MODIS,geographic information system (GIS) and global position system (GPS) is introduced in this paper. Training samples are selected and located with the help of GPS to provide maximal accuracy.A concept of assessing areas of potential cultivation of rice is suggested by means of GIS integration. By integration of MODIS with GIS and GPS technologies the actual areas of rice fields in 2002 have been mapped. The classification accuracy was 95.7% percent compared with the statistical data of the Agricultural Bureau of Zhejiang Province. 相似文献