A New Discipline of Science-The Study of Open Complex Giant System and Its Methodology

This paper introduces the conception of open complex giant system and the methodology for dealing with the system, with stress on its profound significance in development of science and technology. The authors conclude that the reductionism underlying the exact science is not suitable to open complex giant system, and the only feasible alternative is the meta-synthetic engineering from the qualitative to the quantitative.     

剩余半坡

本文提出半坡(p,+,·),在半坡上引进算子“∝”,“■”,得到的代数系统(p,+,·,∝,■)称为剩余半坡,本文给出剩余半坡p的一些基本性质,且证明了(Mn(p),+,·)是剩余半坡。     

流动注射化学发光增强法测定酪氨酸

在Na2CO3-NaHCO3介质中,酪氨酸对Luminol-K3Fe(CN)6化学发光体系有很强的增敏作用.据此建立了流动注射化学发光增强法测定酪氨酸的方法.发光信号的增强值(ΔI)与酪氨酸的浓度在5.0×10-5～4.0×10-7mol/L的范围内呈良好的线性关系,检出限为1×10-7mol/L(S/N=3),对于1.0×10-6mol/L的酪氨酸测定相对标准偏差为2.4%(N=11).该法用于测定医用氨基酸注射液中的酪氨酸,结果令人满意.     

一个安全的主动网络编程语言模型

为解决主动网络安全威胁问题，从编程语言角度分析了语言级的主动网络的安全需求，使用软件机制而不是硬件机制保护主机防止恶意代码攻击，并折中了通信需求和程序语言需求，为主动网络提供了一个安全的编程语言模型。     

Heat shock proteins and infection: interactions of pathogen and host.

Invasive microorganisms encounter defensive attempts of the host to starve, destroy and eliminate the infection. In experimental model systems aiming to imitate defensive actions of the host, microorganisms respond by the rapid acceleration in the rate of expression of heat shock and other stress proteins. Heat shock proteins (hsp) of most if not all pathogens are major immune targets for both B- and T-cells. Host cells involved in the defensive action cannot avoid exposure to their own reactive compounds, such as oxygen radicals, resulting in premature cell death and tissue damage. Long-term consequences to the host may include cancer. In cells in tissue culture, induction of host-specific hsps occurs upon exposure to oxidants and in viral infections. Drugs that bind to members of the hsp70 family induce peroxisome proliferation and hepatocarcinoma, but may open the way for the development of novel drugs in support of antimetabolite treatment of infections and cancer.     

一类优美有向图的充要条件

研究了由恰有一个公共顶点的有向回路→／Ｃｍ和→／Ｃｎ（ｍ，ｎ≥３）组成的有向图→／Ｗｍ，ｎ的优美性，给出了→／Ｗｍ，ｎ是优美有向图的充要条件。     

沉管碎石桩处理软土地基的应用过程

沉管碎石桩是地基处理的方法之一,可以有效地提高地基承栽力,使沉降量减少,增加地基的稳定性,并且可以减少环境污染。对此方法的施工作了详细的介绍。     

Mutation of the matrix metalloproteinase 2 gene (MMP2) causes a multicentric osteolysis and arthritis syndrome.

The inherited osteolyses or 'vanishing bone' syndromes are a group of rare disorders of unknown etiology characterized by destruction and resorption of affected bones. The multicentric osteolyses are notable for interphalangeal joint erosions that mimic severe juvenile rheumatoid arthritis (OMIMs 166300, 259600, 259610 and 277950). We recently described an autosomal recessive form of multicentric osteolysis with carpal and tarsal resorption, crippling arthritic changes, marked osteoporosis, palmar and plantar subcutaneous nodules and distinctive facies in a number of consanguineous Saudi Arabian families. We localized the disease gene to 16q12-21 by using members of these families for a genome-wide search for homozygous-by-descent microsatellite markers. Haplotype analysis narrowed the critical region to a 1.2-cM region that spans the gene encoding MMP-2 (gelatinase A, collagenase type IV; (ref. 3). We detected no MMP2 enzymatic activity in the serum or fibroblasts of affected family members. We identified two family-specific homoallelic MMP2 mutations: R101H and Y244X. The nonsense mutation effects a deletion of the substrate-binding and catalytic sites and the fibronectin type II-like and hemopexin/TIMP2 binding domains. Based on molecular modeling, the missense mutation disrupts hydrogen bond formation within the highly conserved prodomain adjacent to the catalytic zinc ion.