Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer

Since the creation of Dolly via somatic cell nuclear transfer (SCNT), more than a dozen species of mammals have been cloned using this technology. One hypothesis for the limited success of cloning via SCNT (1%-5%) is that the clones are likely to be derived from adult stem cells. Support for this hypothesis comes from the findings that the reproductive cloning efficiency for embryonic stem cells is five to ten times higher than that for somatic cells as donors and that cloned pups cannot be produced directly from cloned embryos derived from differentiated B and T cells or neuronal cells. The question remains as to whether SCNT-derived animal clones can be derived from truly differentiated somatic cells. We tested this hypothesis with mouse hematopoietic cells at different differentiation stages: hematopoietic stem cells, progenitor cells and granulocytes. We found that cloning efficiency increases over the differentiation hierarchy, and terminally differentiated postmitotic granulocytes yield cloned pups with the greatest cloning efficiency.     

信息系统的电磁泄漏及其防护初探

评述信息电子系统的电磁泄漏与耦合机理,及其在恶劣电磁环境中可能带来的危害.讨论了抑制电磁泄漏辐射与传导发射的方法以及测试的相关问题.最后展望了电磁泄漏防护的发展趋势和今后应进一步探讨的相关课题.     

基于延时限制的无线局域网DCF丢包率性能分析

针对无线局域网中具有延时限制的多媒体业务,提出了基于理想信道和有限数目节点假设的带延时约束的DCF接入丢包率分析模型.分析了基本接入方式下给定延时限制的系统丢包率性能并通过仿真验证了分析模型的可靠性.研究结果表明:在固定延时约束条件下,丢包率随系统中节点数量的增加而增大;在固定节点数目时,分组的延时限制越紧,丢包率越高.此外,还研究了初始竞争窗和最大退避阶数对丢包率性能的影响.     

一种基于ebXML的数据交换系统架构

传统的数据交换系统缺乏通用性和扩展性,参与数据交换的各方为了对数据进行封装和解析,需要严格遵循相同的规则.该文提出一种基于ebXML的数据交换系统架构,通过构建符合XML标准的业务流程规范,可以不需要考虑底层数据交换细节进行应用开发,实现数据的无缝对接.     

A Novel Cross-Project Software Defect Prediction Algorithm Based on Transfer Learning

Software Defect Prediction(SDP) technology is an effective tool for improving software system quality that has attracted much attention in recent years. However, the prediction of cross-project data remains a challenge for the traditional SDP method due to the different distributions of the training and testing datasets. Another major difficulty is the class imbalance issue that must be addressed in Cross-Project Defect Prediction(CPDP). In this work,we propose a transfer-leaning algorithm(TSboo...     

基于LabVIEW的串口调试系统设计

串口通信是一种在计算机与计算机之间或计算机与外围设备之间传送数据的常用方法.阐述了基于LabVIEW串口调试系统的设计思路及主要功能,给出了串口调试软件的特点.实践证明,该软件使用方便,功能强大,具有良好的可移植性和可扩展性.     

自媒体时代编辑角色之适应

自媒体在内容、传播速度和传播方式方面都有不同于传统媒体的特点,它们对编辑工作提出了新的要求。传统媒体中的编辑精英化和专业化角色可能在一定程度上不符合自媒体的特征要求,所以需要在一定程度上进行改变。在坚持基本传播理念的前提下,编辑应该在精英化和平民化之间进行平衡,在新媒体时代提高自己的专业和技术水平。     

一类改进的HIV病理模型的全局稳定性

将治愈率引入经典的HIV病理模型,构建一个改进的HIV病理模型.证明了改进模型中无病平衡点的全局稳定性,给出染病平衡点全局稳定性的参数域,并进行了相关的数值模拟,进而发现当染病平衡点不稳定时模型存在周期解.研究结果表明:提高治愈率是有效控制HIV感染的重要途径.     

基于FPGA的交流伺服系统电流环带宽扩展

在电流环的数学模型基础上,分析了电流环带宽与电流环路延时的关系,比较了几种典型电流环时序下产生的延时,对电流采样和PWM占空比更新时序进行了改进,并在FPGA中得到了具体的验证和实现.实验结果表明:这种改进的电流环时序克服了原有电流环时序的问题,能在不改变功率器件开关频率和不损失输出电压能力的基础上减小电流环路延时,从而提高电流环带宽,改善电流环和速度环的控制性能.     

On a dynamic mixture GARCH model

This paper proposes a new mixture GARCH model with a dynamic mixture proportion. The mixture Gaussian distribution of the error can vary from time to time. The Bayesian Information Criterion and the EM algorithm are used to estimate the number of parameters as well as the model parameters and their standard errors. The new model is applied to the S&P500 Index and Hang Seng Index and compared with GARCH models with Gaussian error and Student's t error. The result shows that the IGARCH effect in these index returns could be the result of the mixture of one stationary volatility component with another non‐stationary volatility component. The VaR based on the new model performs better than traditional GARCH‐based VaRs, especially in unstable stock markets. Copyright © 2008 John Wiley & Sons, Ltd.