Synthesis and characterization of bifunctional terbium complex-based nanoparticles

Novel bifunctional terbium complex-based nanoparticles were developed using a modified Stber method and a layer-by-layer assembly process. A magnetic core of Fe3O4 nanoparticles was coated with a silica shell to form the first layer. Then a ternary Tb3+ complex (TESPPA-Tb), which acted as a luminescent marker, was covalently bound to the silica surface by stable Si-O-Si bonds. The TESPPA monomer was synthesized by binding pyridine 2,6-dicarboxylic acid to 3-aminopropyltriethoxysilane, which was used as a ligand for coordination with the Tb3+ ions. An outer shell of silica was applied to the nanoparticles to allow for versatility with surface functionalization. The nanoparticles were characterized by X-ray powder diffraction, transmission electron microscopy, Fourier transform infrared spectroscopy, ultravioletvisible spectroscopy, vibration sample magnetometer, and photoluminescence spectroscopy. The bifunctional nanoparticles exhibited favorable superparamagnetic behavior and photoluminescence properties of Tb3+. These nanoparticles have potential applications in biolabeling, bioseparation, immunoassays, and pathogenic diagnosis.     

Graphene meets biology

Graphene features a shining star in the material sciences since its discovery in 2004. Biomedical application of graphene-family materials has been driven recently. In this paper, we overviewed the cutting-edge research in the biomedical application of graphene-based biomaterials, such as bio-sensing and bio-imaging, drug/gene delivery and scaffold for tissue engineering. We emphasized on the effect of graphene substrates on cellular behaviors of adhesion, proliferation~ and differentiation. The develop- ment of three-dimensional scaffolds based on graphene- based nanomaterials and the potential of these constructs in tissue engineering are discussed. The perspectives and challenges are also addressed.     

基于对比分析的项目管理成熟度模型应用研究

项目管理成熟度模型作为评估和改进组织项目管理能力的重要手段，已得到国外众多项目型组织的认可和应用。本文从等级划分思想、模型构架等方面对比分析了国外目前主要的几种项目管理成熟度模型及其应用情况，旨在为我国项目型组织应用成熟度模型提升自身项目管理能力提供选择的参考。同时，结合我国实际情况，提出了我国企业应用项目管理成熟度模型的基本流程，并对应用过程中应注意的问题进行了分析，并作出结论和展望。     

线性离散时滞系统的鲁棒稳定性分析

依据稳定性理论和矩阵范数理论推导了线性离散时滞系统鲁棒稳定的充分条件,在此基础上得到了不确定时滞离散系统扰动矩阵的范数界,根据不确定离散系统的鲁棒D-稳定的定义,给出了确保不确定离散时滞系统所有极点均位于给定圆形区域系统扰动矩阵的范数界,这些条件形式简单,易于实现,是用于初步检验系统稳定性的有用工具.     

季铵盐 A-l 的相转移催化性能

经实验研究发现具有结构为（Ｃ８～１０Ｈ１７～２１）３Ｎ＋ＣＨ３Ｃｌ－的季铵盐Ａ－ｌ是一种优良的相转移催化剂．在酯化、氧化和烷基化反应中其催化活性要优于聚乙二醇、季磷盐和其它短碳链的季铵盐．Ａ－ｌ在分离过程中不乳化，因而使合成产品易于分离提纯．该催化剂可循环使用，循环使用次数与温度有关．     

判定数据对延迟模型影响的度量

从距离角度讨论数据对延迟模型的影响，建立了延迟模型中的Ｃｏｏｋ距离，并研究了Ｃｏｏｋ距离与相关系数之间的关系。     

计算机硬件课程体系改革与探讨

根据目前计算机硬件课程的现状和存在的问题，对硬件课程教学的课程体系、实验类型、实验室建设提出了一些改革建议，旨在提高计算机硬件课程的教学效果，提高学生实验能力。     

大学生理想信念教育应体现层次性

理想,是人们在实践中形成的符合客观规律的、对未来的向往与追求.大学生理想信念教育是有层次性的,我们在教育过程中要使大学生理想信念教育收到实效,就应遵循人的认识发展规律,循序渐进地、具有层次性地对大学生进行理想信念教育.     

汉魏六朝女诗人作品与李清照词的相通

我国文学史上曾出现过一些优秀的女性作家,比如汉魏六朝的诸位女诗人和宋代的李清照,她们以女性独特的视角透视着整个社会生活,并将它们绘制在文学创作中,或欢快地恋爱,或悲吟着思念,或感喟现实离乱,或抒女子情怀,或豪气万千,或才华横溢,从而丰富了我们的视野,是我国文学史上最宝贵的财富。     

山区公路水毁机理分析及防治措施

依据历年山区公路水毁资料,对山区公路的水毁型式进行了分析,并对其内在机理进行了整理归纳,提出了防治措施,对预防和治理公路破坏具有一定的理论和实际意义.