试论大学生卫生保健工作的信息管理

从系统论的观点来看，学生的卫生保健工作可作为教育系统的一个子系统。本文利用系统、信息庥和控制论的方法，首先试图分析该子系统的功能和各种相互依赖作用的关系，然后提出建立学生卫生保健工作信息管理的初步方案，高等教育的总目标就是培养德、智、体全面发展的高级人才，当然卫生保健工作的优化目标必须从属于该总目标。     

Effects of vitamin B12 on plasma melatonin rhythm in humans: increased light sensitivity phase-advances the circadian clock?

Vitamin B12 (methylcobalamin) was administered orally (3 mg/day) to 9 healthy subjects for 4 weeks. Nocturnal melatonin levels after exposure to bright light (ca. 2500 lx) were determined, as well as the levels of plasma melatonin over 24 h. The timing of sleep was also recorded. Vitamin B12 was given blind to the subjects and crossed over with placebo. We found that the 24-h melatonin rhythm was significantly phase-advanced (1.1 h) in the vitamin B12 trial as compared with that in the placebo trial. In addition, the 24-h mean of plasma melatonin level was much lower in the vitamin B12 trial than with the placebo. Furthermore, the nocturnal melatonin levels during bright light exposure were significantly lower in the vitamin B12 trial than with the placebo. On the other hand, vitamin B12 did not affect the timing of sleep. These findings raise the possibility that vitamin B12 phase-advances the human circadian rhythm by increasing the light sensitivity of the circadian clock.     

Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum.

Shiga toxin and some other protein toxins that act on targets in the cytosol have previously been shown to enter the trans-Golgi network. Transport by this route may be necessary for translocation of the toxin to the cytosol and for intoxication, but it is not known whether the enzymatically active part of the toxins actually enters the cytosol from the trans-Golgi network. It has been suggested that such toxins are transported in a retrograde manner to the endoplasmic reticulum and that translocation occurs in this organelle, but retrograde transport of endocytosed material beyond the trans-Golgi network has never been demonstrated. Here we show that in butyric acid-treated A431 cells endocytosed Shiga toxin is not only transported to the trans-Golgi network, but also to all Golgi stacks, to the endoplasmic reticulum and to the nuclear envelope. Furthermore, butyric acid sensitizes the cells to Shiga toxin, which is consistent with the possibility that retrograde transport is required for translocation of the toxin to the cytosol.     

精密镗削头振动模态的实验研究

通过对国产与进Ｄ的同类型精密镗削头振动模态实验研究，找出了这两种精密镗削头的固有振动频率，给出了它们的各阶动画振型图．从这一侧面解释了国产精密镗削头回转精度偏低的原因。     

管节点疲劳裂纹扩展规律和寿命估算

对Ｔ型管节点的疲劳试验进行分析，研究疲劳裂纹的扩展规律，用“柔度法”计算应力强度因子范围ΔＫ，确定材料常数ｃ，ｍ，提出并运用“直线－曲线模式法”估算管节点疲劳寿命，结果与试验吻合，具有一定的实用参考价值。     

乒乓球运动中的力学分析

利用力学原理分析了乒乓球的运动方程与击球时作用力、球的速度和位置之间的关系．确定出任意条件下的球的落点．并给出了一些计算结果．     

地方性氟中毒流行病及在我国的流行特征

地方性氟中毒是一种在全球流行的地方病。本文介绍了其概念、研究史和研究现状,探讨了地氟病的病理学特征及病区的成因,并初步分析了地氟病在人群中的分布规律及在我国的地理流行特征。