指数化投资的风险评估与预测:基于中国指数基金的实证研究

以我国的指数基金为研究对象, 通过实证方法,检验我国指数化投资的风险状况. 首先,对样本指数基金的跟踪误差方差进行分解, 分析其历史风险水平; 然后,引入压力测试, 预测样本指数基金未来的风险水平. 实证结果表明,从总体上看, 样本指数基金的风险控制得较好. 最后, 发现我国的指数基金能够较紧密地跟踪其基准指数;指数基金的风险来源和结构, 符合指数化投资的风险特征.     

中国法治化进程中的法律信仰

大力进行依法治国,建设社会主义法治国家,是我国现代化进程的必然要求,而法律信仰是社会主体对法的一种特殊的主观把握方式和在理性认识基础上油然而生的一种神圣体验,是对法心悦诚服的认同感和依归感。法治化的过程实质上就是逐步建立法律权威和法律信仰的过程。     

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

We sought to identify new susceptibility loci for Alzheimer's disease through a staged association study (GERAD+) and by testing suggestive loci reported by the Alzheimer's Disease Genetic Consortium (ADGC) in a companion paper. We undertook a combined analysis of four genome-wide association datasets (stage 1) and identified ten newly associated variants with P ≤ 1 × 10(-5). We tested these variants for association in an independent sample (stage 2). Three SNPs at two loci replicated and showed evidence for association in a further sample (stage 3). Meta-analyses of all data provided compelling evidence that ABCA7 (rs3764650, meta P = 4.5 × 10(-17); including ADGC data, meta P = 5.0 × 10(-21)) and the MS4A gene cluster (rs610932, meta P = 1.8 × 10(-14); including ADGC data, meta P = 1.2 × 10(-16)) are new Alzheimer's disease susceptibility loci. We also found independent evidence for association for three loci reported by the ADGC, which, when combined, showed genome-wide significance: CD2AP (GERAD+, P = 8.0 × 10(-4); including ADGC data, meta P = 8.6 × 10(-9)), CD33 (GERAD+, P = 2.2 × 10(-4); including ADGC data, meta P = 1.6 × 10(-9)) and EPHA1 (GERAD+, P = 3.4 × 10(-4); including ADGC data, meta P = 6.0 × 10(-10)).     

翻转教学模式下无机非金属材料工艺学课程教学方法的研究

探索了专业课程无机非金属材料工艺学Ⅰ的教学方法,提出了翻转模式下教学过程的组合模式.该模式下教学内容的贯通式整合与建构有利于教学目标达成,依据金字塔模型理论,该方法学习效果优于以教师为中心的传统模式.实践表明,10 min线上微课+30 min课堂小组讨论+20min师生互动总结,有利于"有意义的传递-主导下探究相结合"教学观念的实施.     

金坛盐穴储气库畸形对盐腔体积影响

金坛盐穴储气库属于层状盐岩型储气库,建设过程中经常出现腔体畸形、偏溶现象,严重降低盐腔有效体积。研究腔体畸形对盐腔体积的影响规律,并在造腔过程中加以控制,将有助于加快库容工作气形成。结合金坛盐穴储气库实际盐腔情况,分析了腔体畸形、偏溶和底坑形状对盐腔有效体积的影响,并根据其形成原因给出了相应解决措施。结果表明,金坛盐穴储气库畸形、偏溶腔体约占总数的30%,畸形系数(11.8～90.1)×10^-3,畸形系数越大盐层利用率越低;畸形导致横截面为椭圆形,且不同深度的腔体直径差别较大,使腔体周围盐层利用率降低;偏溶使井间矿柱宽度过低,矿柱比减小,腔体直径受限,腔体积严重降低;底坑形状可分为“V”形、“一”形、“”形、“A”形4种,其注气排卤效率依次降低,其中,“”形、“A”形最不利盐腔空间利用,严重降低储气体积。对于腔体畸形可采用的控制手段有降低排量、采用正循环、天然气阻溶回溶等技术。对于偏溶可采用预测偏溶方向合理设计井位、降低矿柱比增加腔体直径等措施。底坑畸形尚无有效控制手段和提高注气排卤措施。该研究为后期腔体形状控制和提高盐腔体积奠定了理论基础,将有助于加快金坛盐穴储...     

A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis

Toll-like receptors (TLRs) and members of their signaling pathway are important in the initiation of the innate immune response to a wide variety of pathogens. The adaptor protein Mal (also known as TIRAP), encoded by TIRAP (MIM 606252), mediates downstream signaling of TLR2 and TLR4 (refs. 4-6). We report a case-control study of 6,106 individuals from the UK, Vietnam and several African countries with invasive pneumococcal disease, bacteremia, malaria and tuberculosis. We genotyped 33 SNPs, including rs8177374, which encodes a leucine substitution at Ser180 of Mal. We found that heterozygous carriage of this variant associated independently with all four infectious diseases in the different study populations. Combining the study groups, we found substantial support for a protective effect of S180L heterozygosity against these infectious diseases (N = 6,106; overall P = 9.6 x 10(-8)). We found that the Mal S180L variant attenuated TLR2 signal transduction.     

中国教育人类学新进展——人类学学者访谈录之六十九

经过三十余年的发展,中国教育人类学学科快速发展并取得了一定的成就。作为学科发展历程的亲历者和促进者,滕星教授指出,中国教育人类学目前仍处于"初步学术化"的发展阶段,但正在迈向组织化和专业化发展的新阶段,并随着与国外学术交流的增多、学术共同体的构建和学科知识的积累,该学科很可能在今后一段时期内会进入"井喷式发展"的黄金时期。     

纵向应用形式的渐变折射率棒透镜的光学追迹研究

目前渐变折射率透镜的应用,通常都采用其主轴就是光线传播的光轴（横向应用）的形式,未见主轴垂直光轴应用的纵向应用分析说明。为此进行了相关光学追迹,证明直径中间45％以内光线球差很小。通过数据拟合发现光线在这种情况下满足抛物线函数,对今后DLS快轴准直等工作具有重要意义。     

~7Be在示踪土壤侵蚀过程中的分配规律研究

采用自行设计的试验装置,通过室内淋洗模拟试验分析雨水中7Be质量活度、土壤吸附7Be质量活度及渗漏液中7Be质量活度,对7Be示踪坡面土壤侵蚀的可行性进行研究.试验结果表明雨水中的7Be有73.3%被土壤吸附,只有17.3%进入渗漏液.因此,通过降雨到达地表的7Be主要被土壤吸附,可以用于示踪土壤侵蚀研究.     

高校图书馆开架借阅的科学管理

根据多年的工作实践,指出了高校图书馆开架借阅中产生"破损、丢失、乱架及错借"等问题产生的原因,并提出了开架借阅应采取的科学管理措施.