Molecular Weight Distributions of Cotton Cellulose Treated with a Polycarboxylic Acid at Different pH

In last paper, the average molecular weight of a control cotton fabric and cotton fabrics treated with the polycarboxylic acid at different pH were measured. The result doesn‘t support the hypothesis that the pH of the finishing bath can affect the depolymerization of the finished cotton fabric. In order to understand more about it, the molecular weight distributions of the control and finished cotton fabrics were measured and the reason was fund. From the ratio and the molecular weight of the low molecular part one can see that the pH of the finishing bath can affect the depelymerization of the f‘mished cotton fabrics. The phenomenon that the average molecular weights of the cotton fabric crosslinked with BTCA at different pH are almost same is attributed to that the crosslinks are not broken completely when treated with 0.5 M NaOH solution at 50℃ for 144 h.     

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

Tumour suppressor genes, whose usual function seems to be controlling normal cell proliferation, have been implicated in many inherited and sporadic forms of malignancies Much evidence supports the concept of tumour formation by loss-of-function mutations in suppressor genes, as predicted by the two-hit model of Knudson and DeMars. The suppressor gene, p53, is affected in such a manner by numerous mutations, which occur in a variety of human tumours. These mutations usually represent the loss of one allele and the substitution of a single base in the other. We have now analysed the p53 gene in a family affected by Li-Fraumeni syndrome, a rare autosomal dominant syndrome characterized by the occurrence of diverse mesenchymal and epithelial neoplasms at multiple sites. In some instances the neoplasms seem to be related to exposure to carcinogens, including ionizing radiation. The Li-Fraumeni family that we studied had noncancerous skin fibroblasts (NSF) with an unusual radiation-resistant phenotype. DNA derived from the NSF cells of four family members, spanning two generations, had the same point mutation in codon 245 (GGC----GAC) of the p53 gene. This mutation leads to substitution of aspartic acid for glycine in one of the regions identified as a frequent target of point mutations in p53. The NSF cell lines with the mutation also retained the normal p53 allele. This inherited p53 mutation may predispose the members of this family to increased susceptibility to cancer.     

我国现存有尾类及研究现状分析

本从地理分布特征和数量方面介绍了我国现存的３７种（亚种）有尾类动物,并分析了目前我国有尾类的研究方向和研究现状。     

各种PWM控制方式下的电机共模电压比较研究

研究了不同PWM控制方式下电机共模电压、轴电压和轴承电流的产生机理,建立了脉宽调制逆变器驱动系统共模回路的等效电路,并由此得到轴电压的计算公式.为研究不同PWM控制方式对电机共模电压的影响,建立了电机共模电压仿真模型,比较了在三种PWM控制方式下电机共模电压的仿真波形,通过对仿真结果的对比分析得到了在SPWM控制方式下电机共模电压最小的结论,为逆变器采用哪种控制方式会有最小的轴电压和轴承电流提供了一定依据.     

模块化多电平换流器的快速数字仿真模型

模块化多电平换流器(Modular Multilevel Converter,MMC)拓扑中含有大量电力电子开关元件,因而在基于器件电气物理模块的电磁暂态仿真环境中仿真速度十分缓慢.提出了一种基于简化阻抗变换矩阵的MMC快速数字仿真模型,将电气开关等效为两个状态的可控等效电阻,电容则等效为其暂态等值模型,从而构建了单个子模块的等效阻抗变换矩阵,通过等效电阻串联的方式,简化了矩阵计算,大幅降低了MMC的仿真时间.在Matlab/Simulink环境下搭建了MMC快速数字仿真模型,验证了该模型的有效性.