转动惯量中的微元取法讨论

当计算同一物体绕定轴转动的转动惯量时,选取不同的微元进行积分,得出不同的结果.本文选取不同的微元对同一旋转曲面(空心球壳)和旋转球体绕直径轴转动的转动惯量进行了计算,对结果进行分析比较,总结出求物体转动惯量时,微元取法的规律.     

一类非散度型退化抛物方程广义解的存在性

讨论一类非散度型退化抛物方程的初边值问题. 利用抛物正则化方法, 证明了该问题广义解的存在性. 对初边值和方程做了两重正则化, 并分别进行了一系列的估计. 利用分析方法, 证明了所得逼近解序列的弱收敛性, 进而证明了其弱解的存在性.     

基于董事会治理因素的财务危机预警模型的构建

企业在经营过程中存在着越来越多的财务风险,为了防止这些风险演变为财务危机,及时进行财务危机预警分析,就需要理顺公司的治理结构,引入董事会治理因素来完善财务危机预警机制.以120家上市公司为研究对象,分别运用非参数检验、T检验以及主成分分析对财务变量和董事会治理变量进行筛选,进而运用Logistic回归分析构建预警模型.结果显示,未引入董事会治理变量的模型的预测正确率为92.5%,而引入董事会治理变量的模型预测正确率为94.15%,预警能力明显增强,也说明,董事会治理因素是影响公司财务危机的一个重要方面.     

Introducing an External Terminal Operator or Not? The Decision of Ports in a Duopoly Market

Facing with increasing competition, many ports are taking innovative approaches to improve productivity and profits. Among a variety of methods, introducing external terminal operators(ETOs) while the port acts as a landlord to collect "rents" from those operators for conducting terminal activities inside the port is regarded as an effective way and is commonly observed in practices.This paper analyzes the decisions of two competing ports about whether to introduce their respective ETOs using a three-stage non-cooperative game model when there already exists a port's self-operation terminal operator(STO). At the first stage, the two ports simultaneously decide whether to introduce an ETO. If a port decided to introduce an ETO, at the second stage, it will further decide the unit fee to charge from the ETO. At the third stage, the two ports and the introduced ETO(s) simultaneously decide their respective profit-maximizing output levels. The findings indicate the equilibrium is both ports will introduce their respective ETOs, but when the ports and ETOs are substitutable in the sense of having the same level of productivity, the equilibrium solution is only one port should introduce an ETO. And simulation results show that even if one of ETOs is inefficient this still hold true.     

The industrial asymmetry of the stock price prediction with investor sentiment: Based on the comparison of predictive effects with SVR

As a representative emerging financial market, the Chinese stock market is more prone to volatility because of investor sentiment. It is reasonable to use efficient predictive methods to analyze the influence of investor sentiment on stock price forecasting. This paper conducts a comparative study about the predictive performance of artificial neural network, support vector regression (SVR) and autoregressive integrated moving average and selects SVR to study the asymmetry effect of investor sentiment on different industry index predictions. After studying the relevant financial indicators, the results divide the Shenwan first-class industries into two types and show that the industries affected by investor sentiment are composed of young companies with high growth and high operative pressure and there are a great number of investment bubbles in those companies.     

融合多元触觉和沉浸式视觉的可移植VR软件框架

多元触觉和沉浸式视觉反馈的时空一致性配准以及现有VR软件框架中硬件设备的接入便捷性问题,制约了医疗、商务、娱乐等不同行业中视触觉融合场景的快速开发。为解决这一难题,提出融合多元触觉和沉浸式视觉的可移植VR软件框架,根据视触觉反馈精度要求的不同设计了双层和三层架构兼顾视觉渲染、触觉渲染、硬件控制的不同需求。实验结果表明该框架具有支持视-触融合同步反馈、硬件平台可移植、图形场景开发简便和交互场景可快速替换等特点,能够满足不同领域的交互应用需求。     

多重约束下智慧仓储机器人配置仿真优化研究

针对智慧仓库的仓储机器人配置问题,构建了基于排队论的离散事件仿真模型,在保证系统可靠性和服务强度的前提下,考虑到故障对系统的影响,以距离成本、时间成本、空闲成本和购置成本所构成的总成本最小化为目标,提出了一种基于FlexSim平台的离散事件仿真优化方法。通过分析系统平均队长、订单平均逗留时间等指标,将直观化的系统瓶颈与运行实际数据相结合,求得系统成本最小的配置策略。结合实例,对算例中的智慧仓库机器人配置方案进行求解。结果表明,基于FlexSim平台的离散事件仿真寻优方法,能够求解仓储机器人配置的优化方案,并能保证模型方法的计算效率。     

Defining G protein-coupled receptor peptide ligand expressomes and signalomes in human and mouse islets

Introduction

Islets synthesise and secrete numerous peptides, some of which are known to be important regulators of islet function and glucose homeostasis. In this study, we quantified mRNAs encoding all peptide ligands of islet G protein-coupled receptors (GPCRs) in isolated human and mouse islets and carried out in vitro islet hormone secretion studies to provide functional confirmation for the species-specific role of peptide YY (PYY) in mouse islets.

Materials and methods

GPCR peptide ligand mRNAs in human and mouse islets were quantified by quantitative real-time PCR relative to the reference genes ACTB, GAPDH, PPIA, TBP and TFRC. The pathways connecting GPCR peptide ligands with their receptors were identified by manual searches in the PubMed, IUPHAR and Ingenuity databases. Distribution of PYY protein in mouse and human islets was determined by immunohistochemistry. Insulin, glucagon and somatostatin secretion from islets was measured by radioimmunoassay.

Results

We have quantified GPCR peptide ligand mRNA expression in human and mouse islets and created specific signalomes mapping the pathways by which islet peptide ligands regulate human and mouse GPCR signalling. We also identified species-specific islet expression of several GPCR ligands. In particular, PYY mRNA levels were ~ 40,000-fold higher in mouse than human islets, suggesting a more important role of locally secreted Pyy in mouse islets. This was confirmed by IHC and functional experiments measuring insulin, glucagon and somatostatin secretion.

Discussion

The detailed human and mouse islet GPCR peptide ligand atlases will allow accurate translation of mouse islet functional studies for the identification of GPCR/peptide signalling pathways relevant for human physiology, which may lead to novel treatment modalities of diabetes and metabolic disease.

     

接触网抗风可靠性研究现状及展望

介绍了接触网抗风可靠性研究的国内外现状;并分析了接触网风荷载作用下的失效形式、抗风可靠性的安全界限和破坏准则;对存在的难点及研究方向提出了几点建议。     

Genome-wide association studies of 14 agronomic traits in rice landraces

Uncovering the genetic basis of agronomic traits in crop landraces that have adapted to various agro-climatic conditions is important to world food security. Here we have identified ～ 3.6 million SNPs by sequencing 517 rice landraces and constructed a high-density haplotype map of the rice genome using a novel data-imputation method. We performed genome-wide association studies (GWAS) for 14 agronomic traits in the population of Oryza sativa indica subspecies. The loci identified through GWAS explained ～ 36% of the phenotypic variance, on average. The peak signals at six loci were tied closely to previously identified genes. This study provides a fundamental resource for rice genetics research and breeding, and demonstrates that an approach integrating second-generation genome sequencing and GWAS can be used as a powerful complementary strategy to classical biparental cross-mapping for dissecting complex traits in rice.