全文获取类型
收费全文 | 35028篇 |
免费 | 76篇 |
国内免费 | 118篇 |
专业分类
系统科学 | 338篇 |
丛书文集 | 720篇 |
教育与普及 | 87篇 |
理论与方法论 | 116篇 |
现状及发展 | 15314篇 |
研究方法 | 1398篇 |
综合类 | 16655篇 |
自然研究 | 594篇 |
出版年
2013年 | 200篇 |
2012年 | 486篇 |
2011年 | 1075篇 |
2010年 | 181篇 |
2008年 | 551篇 |
2007年 | 633篇 |
2006年 | 668篇 |
2005年 | 662篇 |
2004年 | 632篇 |
2003年 | 626篇 |
2002年 | 555篇 |
2001年 | 1067篇 |
2000年 | 1033篇 |
1999年 | 654篇 |
1992年 | 632篇 |
1991年 | 543篇 |
1990年 | 578篇 |
1989年 | 501篇 |
1988年 | 520篇 |
1987年 | 557篇 |
1986年 | 537篇 |
1985年 | 691篇 |
1984年 | 558篇 |
1983年 | 450篇 |
1982年 | 370篇 |
1981年 | 394篇 |
1980年 | 521篇 |
1979年 | 1119篇 |
1978年 | 916篇 |
1977年 | 882篇 |
1976年 | 701篇 |
1975年 | 782篇 |
1974年 | 1050篇 |
1973年 | 927篇 |
1972年 | 915篇 |
1971年 | 1113篇 |
1970年 | 1463篇 |
1969年 | 1098篇 |
1968年 | 914篇 |
1967年 | 1014篇 |
1966年 | 916篇 |
1965年 | 648篇 |
1964年 | 165篇 |
1959年 | 386篇 |
1958年 | 612篇 |
1957年 | 466篇 |
1956年 | 419篇 |
1955年 | 351篇 |
1954年 | 382篇 |
1948年 | 282篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
281.
K. R. Middleton F. W. Schaefer H. J. Saz 《Cellular and molecular life sciences : CMLS》1979,35(2):243-244
Summary 4-Isothiocyanato-4-nitrodiphenylamine possessed anthelmintic activity againstNippostrongylus dubius andHymenolepis nana in mice andH. diminuta in rats as determined by both egg counts and recovery of parasites at autopsy. No activity was detected against the cestode,Spirometra mansonoides, in cats.This investigation was supported in part by grants AI-10512 and AI-09483 from the National Institutes of Health. The authors are indebted to Dr P.P. Weinstein for providing animals infected withSpirometra mansonoides. 相似文献
282.
C Radanyi G Redeuilh E Eigenmann M C Lebeau N Massol C Secco E E Baulieu H Richard-Foy 《Comptes rendus des séances de l'Académie des sciences. Série D, Sciences naturelles》1979,288(2):255-258
The antibodies against estrogen receptor were obtained after injecting Rabbits with a cytoplasmic receptor fraction isolated from Calf uterus. The estrogen receptor was partially proteolysed by the action of trypsin and subsequently purified by affinity chromatography (purification 4,000 to 10,000 fold, to a purity of 5-20%). The affinity of the antibody for the proteolysed receptor is KD approximately 1 nM and serum titres have reached values of approximately 50 nM. The values remained constant after the third injection. Preliminary results indicate that the antibody has approximately the same affinity for "native" cytoplasmic estrogen receptor from Calf uterus, as well as for the "trypsinized" forms of estrogen receptor isolated from Calf uterine cytosol and Hen oviduct nuclei. 相似文献
283.
S André N Farjaudon C Pareyre E Séguin 《Comptes rendus des séances de l'Académie des sciences. Série D, Sciences naturelles》1979,288(14):1095-1097
Comparing cytotoxicity of tubulosine and of six newly synthesized pseudo-tubulosines in the Allium test, we have characterized all the current features of protein inhibition. Nevertheless cytotoxicity of the six pseudotubulosines is much weaker. Furthermore, "floating poles anaphasis", a disturbance characteristic of the action of tubulosine, has been found with a lesser intensity with the other compounds. 相似文献
284.
Summary Synthetic 3-methylcyclohex-3-en-1-one, or 3,3-MCH, decreased by 77% the flight aggregation ofDendroctonus pseudotsugae (Scolytidae) to sticky traps containing attractant (frontalin, -pinene, and resin). However, windthrown trees were protected by 3,3-MCH much less than is known to occur with the isomer 3,2-MCH.This research was supported in part by NSF grants BMS 72-02522 and DEB 77-11361 and the O.S.U. School of Forestry. We thank the administration of the Siuslaw National Forest for study sites, and Dr L.M. Libbey for GC/MS of 3,3-MCH. Oregon State University Ag. Exp. Sta. Tech. Paper No. 4313. 相似文献
285.
The levels of membrane alkaline phosphatase have been measured on different lymphocyte fractions from human peripheral blood separated on bovine serum albumin discontinuous gradients. The peak in enzyme activity was observed in a non-T-, non-B-cell fraction, rich in "null" lymphocytes; the lowest values were found in the fraction with the highest proportion of T-cells. 相似文献
286.
Using an automated system for the analysis of amylase, the release of this enzyme was compared in superfused parotid gland segments from control and reserpine treated rats. Stimulant-evoked amylase release was delayed and of smaller magnitude in the glands of the treated animals and a reduction of the transmembrane K+ gradient caused a smaller and short lasting reduction in Ach-evoked release of amylase in the glands from these animals. 相似文献
287.
A thymic extract (TE) was prepared from supernatant of mice thymic epithelial cultures according to the purification of thymosin. TE and thymosin stimulated, in vitro, the immune response of mouse against deep red blood cells. 相似文献
288.
Summary Physostigmine in a dose of 0.1 mg/kg i.v. expressly stimulated the oxygen uptake in the rat cerebral cortex. This effect was blocked by propranolol and seems be mediated by catecholamines. Since atropine also antagonized the stimulant effect of physostigmine, it appears that the action of physostigmine is primarily cholinergic and that the adrenergic effect is a secondary phenomenon. The higher dose of physostigmine (0.4 mg/kg i.v.) caused a depression of rat brain oxygen uptake.This work was supported by a grant from Serbian Republic Scientific Fund (ZMNU SR Srbija), Belgrade (Yugoslavia).The authors wish to acknowledge the skilful technical assistance of Lj. Krsti. 相似文献
289.
Field stimulation of isolated, spirally-cut cervix from day-22 pregnant rats produced contractions which could be inhibited by tetrodotoxin or hyoscine and potentiated by propranolol. The rat cervix would appear to receive both cholinergic and noradrenergic innervations whose transmitters activate muscarinic cholinoceptors and beta-adrenoceptors respectively. 相似文献
290.