康熙己卯顺天乡试案考辨

康熙三十八年发生的己卯顺天乡试案,是康熙朝科场大案之一,不仅牵涉甚广,而且对此后的科举制度发展产生了深远影响.文章主要考察了己卯顺天乡试案的案情始末,并对整个案件的处理情况进行了分析,指出此次科场案件不仅体现了康熙皇帝高明的政治手段和治国策略,更成为清朝科举制度改革的重要契机,由此而生发的各种科场改革对有清一代亦发挥重要作用.     

冀东金矿集中区控矿条件探讨

论述了冀东金矿集中区绿岩型金矿的矿质来源，并恢复其矿源层的原岩。对构造及中小型岩浆任入体的控矿作用作了论述，并提出了成矿模式。     

Preferential hydrophobic interactions are responsible for a preference of D-amino acids in the aminoacylation of 5'-AMP with hydrophobic amino acids.

We have studied the chemistry of aminoacyl AMP to model reactions at the 3' terminus of aminoacyl tRNA for the purpose of understanding the origin of protein synthesis. The present studies relate to the D, L preference in the esterification of 5'-AMP. All N-acetyl amino acids we studied showed faster reaction of the D-isomer, with a generally decreasing preference for D-isomer as the hydrophobicity of the amino acid decreased. The beta-branched amino acids, Ile and Val, showed an extreme preference for D-isomer. Ac-Leu, the gamma-branched amino acid, showed a slightly low D/L ratio relative to its hydrophobicity. The molecular basis for these preferences for D-isomer is understandable in the light of our previous studies and seems to be due to preferential hydrophobic interaction of the D-isomer with adenine. The preference for hydrophobic D-amino acids can be decreased by addition of an organic solvent to the reaction medium. Conversely, peptidylation with Ac-PhePhe shows a preference for the LL isomer over the DD isomer.