Intercellular bridges of chick blastoderm studied by scanning and transmission electron microscopy

Summary Chick blastoderms were studied by scanning and transmission electron microscopy to identify by both methods a type of thread-like structure lying on the epiblast. The structure was identified by transmission microscopy as a long telophase bridge containing mid-body and spindle remnant. It apperas to provide cytoplasmic continuity between only 2 cells.Supported by a grant from The Medical Research Council of Canada.     

X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment

Epilepsy and mental retardation limited to females (EFMR) is a disorder with an X-linked mode of inheritance and an unusual expression pattern. Disorders arising from mutations on the X chromosome are typically characterized by affected males and unaffected carrier females. In contrast, EFMR spares transmitting males and affects only carrier females. Aided by systematic resequencing of 737 X chromosome genes, we identified different protocadherin 19 (PCDH19) gene mutations in seven families with EFMR. Five mutations resulted in the introduction of a premature termination codon. Study of two of these demonstrated nonsense-mediated decay of PCDH19 mRNA. The two missense mutations were predicted to affect adhesiveness of PCDH19 through impaired calcium binding. PCDH19 is expressed in developing brains of human and mouse and is the first member of the cadherin superfamily to be directly implicated in epilepsy or mental retardation.     

商业银行个人理财业务的发展与对策

介绍了个人理财的发展概况,阐述了商业银行个人理财定位的误区,在分析个人理财业务发展环境的基础上,探讨了个人理财业务的市场发展趋势及对策。     

盐酸羟胺还原-亚铜试剂显色树脂相分光光度法测定痕量Cu(Ⅰ)

在pH4.50的酸性介质中,亚铜试剂与Cu(Ⅰ)生成紫色配合物,与强酸性阳离子交换树脂交换吸附,可进行树脂相分光光度法测定痕量Cu(Ⅰ).最大吸收波长λmax为520nm;表观摩尔吸光系数ε为6.8×104L.mol-1.cm-1;Cu(Ⅰ)在0～1.48mg.L-1范围内符合Beer定律.用此法测定天然水中痕量Cu(Ⅰ),结果满意.     

Stability of expression-linked surface antigen gene in Trypanosoma equiperdum

African trypanosomes evade clearance in immune-competent hosts by periodically replacing their major surface glycoprotein with an antigenically different glycoprotein. Expression of many of these variant surface glycoproteins (VSGs) is associated with the duplication and transposition of silent basic copy genes (BCs) into unlinked genomic expression sites. The new expression-linked VSG gene copies (ELCs) are oriented with their 3' ends proximal to chromosome telomeres. Other VSG genes are activated without the production of an ELC. The 3' ends of these VSG genes are near chromosome telomeres both when they are active and when they are inactive. Recently, we have shown that activation of the VSG-1 gene in the BoTaR (Bordeaux trypanozoon antigen repertoire) serodeme of Trypanosoma equiperdum involves the duplication and transposition of a telomeric BC gene into one of at least three unlinked telomeric sites. Here we show that the VSG-1 ELC is inactivated but not eliminated in some antigenic variants derived from a VSG-1 expressor. In addition, a subsequent variant that again expresses VSG-1 has not reactivated the residual VSG-1 ELC (R-ELC), but instead contains a new, active VSG-1 ELC in an unlinked telomeric site. These results show that the simple presence of an ELC in a potential expression site is not sufficient for its expression.     

高技术指标：2007年度33国(地区)技术竞争力报告

文中的高技术指标（High Tech Indicators,HTI）为佐治亚理工大学发布的沿用多年的指标。数据对
比的时间段分别为1993年、1996年、1999年、2002/3年和2007年。论文给出了33个国家（地区）当前的竞争
力指标——技术排名(Technological Standing, TS), 同时提供了四个表征未来竞争力前景的主要指标——国家
发展取向指标(National Orientation, NO)、社会经济基础指标(Socio-Economic Infrastructure, SE)、技术基础指
标(Technological Infrastructure, TI)与生产能力指标(Productive Capacity, PC)。论文无意在高技术指标的结果上
多加笔墨,但是也的确注意到,中国已经取代美国占据了技术排名的首位。这一结果反映了高技术指标的特
点,更重要的是,它反映了中国过去15年的惊人发展速度。     

隔板对燃烧室压力高频自激振荡的抑制作用

隔板在抑制液体火箭发动机高频燃烧不稳定性方面具有重要作用。该文研究隔板对液体火箭发动机中自激高频燃烧不稳定性的抑制作用机理。在初边值条件不施加任何激励的情况下,首先对无隔板的液氧/煤油模型发动机中的气液两相非稳态燃烧过程进行数值模拟,获得的燃烧室压力和流向平均速度与实验结果相符,并得到了燃烧室中的压力自激振荡。研究了隔板对这种压力自激振荡的抑制作用,并分析了压力波随时间的传递与演化过程。结果表明:无隔板燃烧室中发生了高频不稳定燃烧,频谱分析显示其具有1阶横向振型与2阶纵向振型;引入隔板后,燃烧室中的压力振荡减弱,且其横向振型消失,只有2阶纵向振型。结合燃烧室中压力波的传递和演化过程进行分析可知,压力自激振荡源主要出现在头部附近的区域,隔板的加入可以有效抑制压力波的横向传播,并提高激发不稳定燃烧所需的能量,从而抑制燃烧不稳定性的发生。