Quantitative distribution of glucose-6-phosphate dehydrogenase and isocitric dehydrogenase in the human nephron

Zusammenfassung In den einzelnen Abschnitten des menschlichen Nephrons und in Nierenhomogenaten wurden quantitativ die Glucose-6-phosphat-dehydrogenase-und die Isozitronens?uredehydrogenase-Aktivit?t gemessen.

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This investigation was made possible by a grant from the Swiss National Foundation for the Development of Scientific Research. The technical assistance of MissD. Keller is gratefully acknowledged.     

The interpretation of genetical data

Zusammenfassung Für die Interpretation genetischer Ergebnisse wird den Autoren vorgeschlagen, Grundannahmen jeweils ausführlich zu formulieren.     

Licht- und elektronenmikroskopische Befunde an den Geschmacksknospen der Axolotlzunge

Summary The investigation of the taste buds in the tongue of the neotene Mexican axolotl (Siredon mexicanum) by light and electron microscopy demonstrates 4 different cell types: 1) R-cells, marginal cells of less differentiated character. 2) G-cells, granulated cells in basal position. 3) Cells of type A with fibrills, vesicular elements, and dark bodies, showing supporting and secretory function. 4) Cells of type B with an agranular endoplasmic reticulum in stripe like arrangement, supposed to be receptor cells.     

Difference in electrical activity during wakefulness and the phase of ‘sleep with muscular twitches’ as recorded from the cortex of the marsupialDidelphis azarae (South American opossum)

Resumen Se ha observado una neta diferencia entre los registros electroencefalográficos de la vigilia y la fase de « Sueño con sacudidas musculares » del MarsupialDidelphis azarae según sea la posición de los electrodos sobre la corteza cerebral.     

Amplification of immunoglobulin lambda constant genes in populations of wild mice

The lambda immunoglobulin light chain (Ig lambda) locus of BALB/c inbred mice consists of two variable region gene segments (V lambda)1-3, and four constant region gene segments (C lambda)1,2,4,5. Each C lambda gene segment is associated with a unique joining segment (J lambda)2,4-7, and they are organized in two paired units, J3C3-J1C1 and J2C2-J4C4 (refs 4, 8). Using cDNA probes specific for C lambda 1 and C lambda 2 (ref. 9) we have analysed the genomic organization of the C lambda gene segments in wild-derived and inbred strains of mice. Although Southern blots of the genomic DNA of inbred mice show a constant pattern of hybridization, wild-derived mice show a high degree of variation in the number, size and intensity of hybridizing fragments. We have now found that, per haploid genome, mice of a Mus musculus musculus stock isolated from Sladeckovce, Czechoslovakia (CzII) have at least 12 C lambda segments, and mice of a Mus musculus domesticus stock 'Centreville Lights' from Centreville, Maryland (CL) have at least 8 C lambda segments. There appears to have been relatively recent amplifications of the C lambda gene segments in wild mice.