拟面向对象和面向对象智能决策支持系统开发环境

根据实际开发的经验，探讨拟面向对象和面向对象型智能决策支持系统开发环境的设计思想、基本结构、六大功能模块对象类库及用该环境开发拟面向对象型和面向对象型决策支持系统的有关步骤。     

无限维离散不可控系统二次判据问题讨论

通过构造一个范数，并利用动态规划原理对无限维离散不可控系统二次判据问题进行了讨论，得到了最优反馈控制的存在唯一性，以及自治情形下的Ｒｉｃｃａｔｉ方程。     

一种标定立体成像系统的新方法

在立体成像系统中，两相机的位置、取向、倾角由于机械上的困难，很难保证固定不变。因此，在匹配问题解决后，必须对成像系统进行标定，才能最终提取关于景物的三维信息，基于此，提出了一种成像系统的模型及其误差量定义，同时给出了用最小二乘法拟合立体成像系统参数的算法。     

一种立体视觉图像的特征选择与匹配方法

从立体图像对中获取精确的三维信息需要进行相机建模、标定和图像点的匹配［１，２］．提出了特征点的选取；利用金字塔图像结构进行立体匹配，以及对匹配点进行整体性检验的准则。实验表明，该算法匹配速度快，错误概率小，匹配点在整个景物中分布均匀。     

基于小波包的信号检测算法

针对多个相似信号分量的到达时间检测问题提出了一种基于小波包理论的新算法（ＷａｖｅｌｅｔＰａｃｋｅｔｓＤｅｔｅｃｔｉｏｎＡｌｇｏｒｉｔｈｍ，ＷＰＤＡ）．即使在各信号分量严重重叠的情况下，该算法都能非常精确地确定各分量的到达时间。为了进行比较，引用了Ｂ．Ｆｒｉｅｄｌａｎｄｅｒ提出的改进Ｇａｂｏｒ表征方法（ＩＧＲＭ）及其信号模型。实验证明，小波包检测算法可以得到更为优越的性能。还讨论了小波包检测算法中的正交镜像滤波器选择问题。     

基于LPC预测误差DWT的语音基音检测

在对语音信号进行ＬＰＣ分析的基础上，提出了一种有效的语音基音周期检测算法。该算法利用小波变换中著名的Ｍａｌｌａｔ算法逐层分解ＬＰＣ预测误差信号，在最低分辨率的逼近信号中寻找峰值，然后逐层回溯各个分辨率的逼近信号，最后在ＬＰＣ预测误差中确定出峰值，从而求出相应的基音周期。     

Protective effect of Shigyaku-to,a traditional Chinese herbal medicine,on the infection of herpes simplex virus type 1 (HSV-1) in mice

The antiviral activity of Shigyaku-to (TJS-109), a traditional Chinese herbal medicine, was investigated in mice infected with herpes simplex virus type 1 (HSV-1). TJS-109 is a combination of the medicinal plant extracts fromZingiberis siccatum rhizoma,Aconiti tuber andGlycyrrhizae radix in a specific proportion. Mice infected with a 10 LD₅₀ dose of HSV-1 were treated with TJS-109 orally at doses of 1.25 to 20 mg/kg 2 days before, and 1 and 4 days after the infection. The treated groups had 80% (1.25 mg/kg), 40% (5 mg/kg) and 23% (20 mg/kg) mortality rates 25 days after the infection as compared with a 100% mortality rate in control mice treated with saline. When HSV-1 infected mice (recipients) received CD8⁺T cell fractions derived from spleens of mice treated with TJS-109 (donors), 70% of recipients survived, as compared with 0% survivors in the groups of mice treated with saline, B cell fractions, CD4⁺ T cell fractions or macrophage-enriched fractions prepared from the same donors. TJS-109 did not show any virucidal activities against HSV-1 or any virostatic activities on the growth of HSV-1 in Vero cells. These results suggest that TJS-109 protected mice exposed to lethal amounts of HSV-1 through the activation of CD8⁺ T cells.     

A morphometric study of spermatogenesis in the testes of mice of a senescence accelerated strain

The morphometric parameters of spermatogenic cells in a mouse strain prone to accelerated senescence (SAM-P), a novel murine model of spontaneously promoted aging, were compared with those of a SAM resistant strain (SAM-R) after birth until 40 weeks (mean life span of SAM-P). A mixture of gonocytes and spermatogonia were present in the testis in 1-week-old mice, and no gonocytes were observed in 2-week-old mice. At 6 weeks of age, the absolute number of spermatogonia in SAM-P was 27% greater than that in SAM-R, whereas the cell number in 40-week-old SAM-P was 17% less than in SAM-R. Primary spermatocytes were first observed in 3-week-old animals, and the cell numbers in SAM-P at 3, 5 and 6 weeks were 78%, 31% and 25%, respectively, greater than in SAM-R, whereas the cell number in SAM-P at 40 weeks was 30% less than SAM-R. Round spermatids were first observed in all SAM-P at 4 weeks old, but 20% of SAM-r had no spermatids and the rest had only a few. At 5 and 6 weeks old, the absolute numbers of round spermatids in SAM-P was about 34% and 41%, respectively, greater than in SAM-R, whereas the cell number in 40-week-old SAM-P was about 34% less than SAM-R. These results indicate that testicular maturation begins at an earlier age in SAM-P than SAM-R. Furthermore, at the age of 40 weeks signs of testicular deterioration are evident in SAM-P mice only     

The effect of corticotropin-releasing factor and pro-opiomelanocortin-derived peptides on the phagocytosis of molluscan hemocytes

The effect of corticotropin-releasing factor (CRF) and pro-opiomelanocortin (POMC)-derived peptides on hemocyte phagocytosis in two molluscs,Planorbarius corneus andViviparus ater was studied. The peptides and related fragments examined are those which have been shown to influence hemocyte motility in the two species. The results obtained revealed that the effects on phagocytosis are not directly correlated with previous findings on cell motility. Furthermore, the mode of action of an individual peptide could be species-specific and dose-dependent. The relationships between peptides, locomotion and phagocytosis in these molluscs are discussed.     

Inhibition of glucose transport in human erythrocytes by 2,3-dioxoindole (Isatin)

10 mM isatin (2,3-dioxoindole) inhibited glucose influx into human erythrocytes by over 30%. The inhibition is of the competitive type, where the affinity constant (K_t) was increased from 5.71 (control) to 11.11 mM in the presence of isatin with no change in V_max (130 nmol/min/ml packed cells). The observed inhibition of sugar transport by isatin was not mediated through membrane–SH groups accessible to iodoacetate, iodoacetamide, DTNB, DNP or sodium arsenite. Isatin inhibited sugar transport in the presence of 2 mM harmaline, an alkaloid inhibitor of Na⁺, K⁺–ATP_ase activity. The inhibition was non additive which suggests that these two compounds interact with the same or a similar site on the erythrocyte membrane.