Effects of monosodium glutamate on circulating concentrations of luteinizing hormone and growth hormone in young growing domestic fowl (Gallus domesticus)

Summary The administration of monosodium glutamate (MSG) at a dose of 4 g/kg in 5-day-old fowl or 5 daily injections of MSG (total dose 20 g/kg) in 1- to 5-day-old fowl did not affect body growth in either male or female domestic fowl. Neither MSG treatment schedule affected either testis weight or the circulating concentration of luteinizing hormone (LH). A small, but significant decrease in the plasma concentration of growth hormone (GH) was observed in female chicks which had received daily MSG injections.Acknowledgments. Paper of Journal Series, New Jersey State Experiment Station, project No. 18141 and 18443, supported by State and Hatch Act funds and grants from the National Science Foundation (PCM 80227227) and the Upjohn Company.     

Effect of acetylsalicylic acid on iron absorption in the rat

Summary The in vivo administration of⁵⁹Fe to the rat accompanied by acetylsalicylic acid (ASA) enhanced significantly counts in blood, spleen, liver and femur without affecting those of the intestine. The results suggest that ASA augments iron absorption either via an inhibitory action on the synthesis of prostaglandins or by a purely chemical mechanism.This work was supported by Grant No. 6638 from CONICET (Argentina).The technical assistance of Mrs María E. Castro and Mrs Patricia Dubra is gratefully acknowledged.     

Effect of alcohol ingestion on the epithelial cell population in rat small intestine

Summary Chronic administration of alcohol to well-nourished rats led to striking changes in the small intestinal cell population. The present experiments corroborate the view that alcohol is directly toxic to the small intestine.The authors wish to thank Mr.P. R. Gaspar for the technical assistance.     

Delay of normal development of sea urchin embryos by cytosine arabinoside

Résumé Le développement des ufs d'oursins est ralenti par la cytosine arabinoside à laquelle on les expose pendant 4 à 8 h, mais il reprend son cours après le traitement.

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This research was performed at the Naples Zoological Station in August of 1965 and was supported by an American Table award from the American Institute of Biological Sciences. I wish to thank Dr.A. Orengo for his kind assistance during my stay at the Station and to the director,P. Dohrn, for his hospitality.     

Kinetics of insulin secretion in response to glucose by isolated islands of Langerhans from the fetal rat]

Isolated islets of Langerhans from 21.5 day-old foetal Rats were studied in a perifusion system in vitro. The overall dynamics of insulin release by the foetal islets in response to glucose 13.9 mM is biphasic and qualitatively similar to that obtained with islets of adult Rats. The magnitude of the initial phase of insulin secretion is similar for the foetal and adult islets. The second phase is fourfold higher in the adult than in the foetus. The response of foetal islets occurs, 45 to 60 sec. after the increase of glucose concentration in the medium and a maximum insulin release for the first phase is obtained with a lag period of 2 min. The difference between foetal and adult islets is essentially quantitative.