High-frequency induction in vivo of mouse leukemia in AKR strain by 5-azacytidine and 5-iodo-2′-deoxyuridine

Zusammenfassung Nachweis der leukämogenen Wirkung von 5-Azacytidin und 5-Jod-2-Desoxuridin beim Stamm der AKR-Mäuse. Es wird angenommen, dass es sich hierbei um eine Virusinduktion handelt.     

Lipolytic effect of insulin and other hormones in vitro in aortic tissue of experimental animals

Zusammenfassung In der Aortenwand von Ratten, Meerschweinchen, Kaninchen und Schweinen wird eine hormonempfindliche Lipase beschrieben, die in vitro durch Katecholamine, ACTH und Glucagon beeinflusst wird. Glucagonfreies Insulin wies eine deutliche lipolytische Wirkung auf und unterschied sich dadurch von der Wirkung im Fettgewebe.     

Isoenzyme of some dehydrogenases and nonspecific esterase in experimental virus hepatitis in mice

Zusammenfassung Verschiedene Dehydrogenasen, die physiologischerweise nur in der Leber vorkommen, wurden bei Virushepatitis der Mäuse in fortgeschrittenem Stadium auch im Blut gefunden.     

Gonadotropin receptors,cAMP and testosterone in estrogenized male rats

Summary In neonatally estrogenized and PMSG-treated rats, binding of¹²⁵I-HCG to testicular receptors correlates with levels of plasma testosterone, but not with formation of cAMP.     

Scanning-autoradiography—a new method for the demonstration of membrane-surface-associated structures

Summary A method for the demonstration of membrane-localized markers and receptors is described which results from the combination of autoradiography and scanning electronmicroscopy.     

Experimental production of local osteomalacia

Summary The newly deposited bone which was laid down on necrotic bone in the experimentally produced osteochondral chips in the knee joint of 16 sheep and rabbits remained unmineralized and undermineralized in which respect it resembled osteomalatic bone. Local factors which interfere with the mineralisation of a new covering bone should be considered in the pathogenesis of osteomalacia, in healing of aseptic bone necrosis and fractures, and incorporation and fate of bone transplants.This project was partly supported by the Action Research for the Crippled Child, grant No. A/8/877.     

Nuclear degeneration induced by chlortetracycline

Summary After application of chlortetracycline to plants, a degeneration of nuclei, manifested by dilatation and vacuolation of the nuclear membrane, occurs in the mesophyll cells of the sunflower plant.