An Analysis of the Kinetic Features of Scissor Elevator Mechanism and Its Optimized Design

A mathematical model has been established for the research on scissor elevator for ship passenger stairs.The kinematical and kinetic simulation analyses were carried out with MATLAB/Simulink.The relative kinetic relation between hydraulic cylinder and other parts,as well as its rules of change has been found.A 3-D model of ship scissor elevator was established with Pro/E.The design of the mechanism was optimized in Pro/MECHANICA based on the findings from simulation analysis.Practice has proved that the design is scientific and reasonable and could serve as the theoretical guidance and reference for the design of scissor mechanism of other uses.     

浅谈林场职工思想政治教育工作

对于林杨职工来说,构建和谐的人际关系,既是构建社会主义和谐社会的必然要求,同时也为新时期林场思想政治工作指明了目标和方向.     

《科学》课程改革的核心是改变知识结构

课程改革的核心问题是改变课程结构，从而使学生建立适应社会的知识结构。文章从反思原来课程对学生知识结构的影响，现代社会所需人才的知识结构，在科学教学中使学生形成合理的知识结构三个方面论述中心论点。     

MAPK/ERK1/2 signaling mediates endothelial-like differentiation of immature DCs in the microenvironment of esophageal squamous cell carcinoma

Endothelial-like differentiation of dendritic cells (DCs) is a new phenomenon, and the mechanism is still elusive. Here, we show that the tumor microenvironment derived from the human esophageal squamous cell carcinoma (ESCC) cell line EC9706 can induce immature DCs (iDCs) differentiate toward endothelial cells, and become endothelial-like cells, but it has no obvious influence on mature DCs. During the course of endothelial-like differentiation of iDCs, a sustained activation of mitogen-activated protein kinase/extracelluar signal-regulated kinase1/2 (MAPK/ERK1/2) and cAMP response element-binding protein (CREB) was detected. Incubation of iDCs with MEK phosphorylation inhibitor PD98059 blocked the MAPK/ERK1/2 and CREB phosphorylation as well as the endothelial-like differentiation of iDCs. Inhibition of vascular endothelial growth factor-A (VEGF-A) in the microenvironment with its antibody blocked the endothelial-like differentiation and the phosphorylation of MAPK/ERK1/2 and CREB. These data suggest that MAPK/ERK1/2 signaling pathway activated by VEGF-A could mediate endothelial-like differentiation of iDCs in the ESCC microenvironment.     

试论高校学生组织体制的改革

高校体制改革使学生组织内外环境发生了变化，从而出现新情况、新问题，这些具体条件的变化要求学生组织体制也应该进行相应的变革，充分体现师生共同活动的统一和互动，充分发挥大学生的主体性，主动性和创造性。目前高校学生组织机制的重新设计和建构还是一个尚未开发的重要体制资源，值得探讨。     

网络营销的经济分析

随着网络的发展,网络营销受到越来越多的关注,文章试从其产生的背景、网络营销的特点、营销方式及其与传统营销之间的关系来对网络营销这种现象作一个简单的经济分析.     

刚体瞬时运动合成的一种实用方法

关于刚体瞬时运动的合成问题，尚无一个规范方法。本文给出解决这类问题的一种新方法，它是利用给定运动的参量与力学的元素这两类量的相似比拟来求解。     

一种基于“流”的复合系统协调管理模型

对可用于复合系统协调管理建模的方法作了分析，并以区域经济，资源，环境协调发展问题为背景，探讨了一种基于“流”的复合系统协调管理模型的建模及协调控制方法，并就一简单的经济－资源－环境复合系统，建立了基于“流”的协调管理模型。     

基于坐标测量机的多智能主体检测规划知识框架的实现

ＤＩＫＦ是在基于分布式并行处理智能检测规划集成开发平台中，用于多智能主体协同求解的分布式检测规划知识模型框架．论文主要论述了ＤＩＫＦ的系统组织原则和组成ＤＩＫＦ的智能主体的内部结构和功能模块，并依据其内部结构说明了分布式检测规划的协同求解方法和策略．     

结合最优类别信息离散的细粒度超网络微阵列数据分类

针对传统演化超网络只能有效处理二值数据输入的问题，提出一种结合最优类别信息离散（Optimal Class-Dependent Discretization， OCDD)的细粒度演化超网络模型，对连续数据进行离散化生成细粒度二进制编码，并通过对其进行演化学习得到具备决策能力的超网络分类器.该方法避免了传统超网络模型对连续数据进行直接二值化后的高信息损失，使演化超网络的概率估计更接近于数据真实分布，提高了超网络的决策分类能力.对结肠癌、肺癌、前列腺癌和急性白血病4种DNA微阵列数据集进行实验的结果表明，结合OCDD的细粒度演化超网络具有比传统演化超网络更高的识别率和鲁棒性.