方竹笋残渣不溶性膳食纤维制备工艺研究

为开发利用方竹笋残渣,采用酸碱法制备膳食纤维;以不溶性膳食纤维得率为指标,分别考察各因素对制备工艺的影响。结果表明,在碱液pH为12.5、温度60℃、料液比1∶10、浸泡时间2 h和酸液pH为2、浸泡温度60℃、料液比1∶8,浸泡时间1.5 h的条件下,方竹笋残渣不溶性膳食纤维得率为52%,持水力为5.19 g/g,膨胀力为5.72 mL/g,持油力为7.16 g/g。     

Treatment of PC-3 cells with ultrasound combined with microbubbles induces distinct alterations in the expression of Bcl-2 and Bax

The objective of the present study was to investigate whether ultrasound combined with microbubbles induces apoptotic cell death in androgen-independent prostate cancer cells and to identify the probable mechanism. We used ultrasound in continuous wave mode with a frequency of 21 kHz and a spatial-average temporal-average intensity of 46 mW/cm². Ultrasound combined with microbubbles (200 μL SonoVue?) was used to treat androgen-independent human prostate cancer PC-3 cells for 30 s. PC-3 cells were divided into three groups: the control group, the ultrasound group and the ultrasound combined with microbubbles group. Immediately after treatment, trypan blue exclusion was used to assess cell viability. Cell apoptosis at 24 h after treatment was measured using transmission electron microscopy and flow cytometry. Western blotting was used to evaluate the expression of the apoptosis-related proteins, Bcl-2 and Bax. Ultrasound combined with microbubbles had a minimal effect on the viability of PC-3 cells and induced minimal levels of cell lysis. The level of apoptosis in PC-3 cells induced by this modality was significantly higher than in controls (12.77 ± 0.31% vs. 2.56 ± 0.22%, P<0.01). Treatment with ultrasound combined with microbubbles increased the expression of Bax, a pro-apoptotic protein, and decreased the expression of Bcl-2, an anti-apoptotic protein. It was concluded that ultrasound combined with microbubbles induces apoptotic cell death in human prostate cancer PC-3 cells through down-regulation of Bcl-2 and up-regulation of Bax.     

基于SWOT的福州临空经济发展研究

福州是海峡西岸经济区的省会中心城市,发展临空经济,机遇良好,并具备一定的优势因素,但也面临相应的制约条件。福州应正确认识现状,充分利用和不断扩展空港资源,明确临空经济发展的总体思路,加强规划引导,完善基础配套,构建与其资源禀赋相符的产业体系,促进临空经济规模发展。     

快速沉积的金刚石薄膜生长特性

本文研究了用直流电弧等离子体喷射法快速沉积的金刚石薄膜的生长特性,并与用热解CVD法沉积的金刚石薄膜生长特性做了比较。     

Mechanism of brittle-ductile transition of a glass-ceramic rigid substrate

The hardness, elastic modulus, and scratch resistance of a glass-ceramic rigid substrate were measured by nanoindentation and nanoscratch, and the fracture toughness was measured by indentation using a Vickers indenter. The results show that the hardness and elastic modulus at a peak indentation depth of 200 nm are 9.04 and 94.70 GPa, respectively. These values reflect the properties of the glass-ceramic rigid substrate. The fracture toughness value of the glass-ceramic rigid substrate is 2.63 MPa·m1/2. The material removal mechanisms are seen to be directly related to normal force on the tip. The critical load and scratch depth estimated from the scratch depth profile after scratching and the friction profile are 268.60 mN and 335.10 nm, respectively. If the load and scratch depth are under the critical values, the glass-ceramic rigid substrate will undergo plastic flow rather than fracture. The formula of critical depth of cut described by Bifnao et al. is modified based on the difference of critical scratch depth     

Design and fabrication of superconducting HEB mixer

This paper describes the design and fabrication of superconducting hot electron bolometer （HEB） mixer based on ultra-thin superconducting NbN films. The high quality films were epitaxially grown on high resistance Si substrates. The device was fabricated by magnetron sputtering, electron beam lithography （EBL）, reactive ion etching （RIE）, lithography, and so on. The device＇s resistance-temperature （R-T） curves and current-voltage （I-V） curves were studied. The results of THz response of the device are presented. Y-factor technique was used to measure the device＇s noise temperature. When the device was irradiated with a laser radiation of 2.5 THz, the obtained lowest noise temperature of the device was 2213 K.     

表面活性剂对稀土荧光反应的影响——Ⅰ 离子型表面活性剂存在下 Ln~(3+)(Ln=Sm,Eu,Tb)-β-二酮、Ln~(3+)-β-二酮-有机碱及水溶性体系的荧光光谱

讨论了阴离子型表面活性剂(SDS)和阳离子型表面活性剂(CTMAB、Zeph 和 CPC)对 Ln~(3+)-β-二酮二元体系、Ln~(3+)-β-二酮-Phen(或 DPG)三元体系及 Tb~(3+)-AA-EDTA、Tb~(3+)-Tiron、Tb~(3+)-H_2Sal-EDTA 水溶性体系荧光光谱的影响,发现不同的表面活性剂对不同的反应体系影响不尽一致.增敏程度与表面活性剂和荧光配位体的结构有关。     

Development of a middle and low latitude theoretical ionospheric model and an observation system data assimilation experiment

On the basis of previous work, we develop a middle and low latitude theoretical ionospheric model in this paper, named Theoretical Ionospheric Model of the Earth in the Institute of Geology and Geophysics, Chinese Academy of Sciences （TIME-IGGCAS）. TIME-IGGCAS solves the equations of mass continuity, motion and energy of electron and ions self-consistently and uses an eccentric dipole field approximation to the Earth＇s magnetic field. We combine the Eulerian and Lagrangian approaches in the model and take account of the plasma ExB drift velocity. Calculation results reveal that the model is steady and credible and can reproduce most large-scale features of ionosphere. By using TIME-IGGCAS, we carried out an observation system data assimilation experiment. Assimilation results show that the ExB drift velocity can be accurately estimated by ingesting the observed foF2 and hmF2 into the model applying nonlinear least-square fit method. We suggest that this work is of great significance in the development of ionospheric data assimilation model to give better nowcast and forecast of ionosphere.     

An Improved Identity-Based Society Oriented Signature Scheme with Anonymous Signers

In this paper, we present an improved identity-based society oriented signature scheme with anonymous signers, which satisfies： （1） when members leave or join an organization, the public verification key and the signature verification procedure are unchanged; （2） a user participates in several organizations at the same time, her secret key is only related with her identity. However, no previous schemes have these two properties.     

青藏公路冻土路基最大设计高度研究

针对冻土路基斜坡稳定性受温度场影响的特殊性,采用自行开发的数字路基仿真平台对不同地温、不同坡度和不同路基高度条件下的大量工况进行了温度场数值模拟。采用冻土力学参数与地温的拟合公式将温度场与力学场关联起来,并考虑到冻融交界面作为软弱夹层对于冻土路基稳定性控制作用,采用自行编制的冻土斜坡稳定性评价程序对各工况进行了稳定性系数计算,并考虑了荷载作用对冻土路基斜坡稳定性的影响。参照《公路路基设计规范》中对于路堤软弱层滑动稳定性的设计规定,提出了不同坡比、不同荷载作用条件下的冻土路基最大设计高度。