一种可能的类热态——双温态

一种可能的类热态──双温态赵峥，朱建阳，王永成，Ｂ．Ｍｉｓｒａ（北京师范大学物理学系，１００８７５，北京；抚州师范专科学校物理学系，３４４０００，江西抚州；ＳｃｈｏｏｌｏｆＰｈｙｓｉｃａｌＳｃｉｅｎｃｅｓ，ＪａｗａｈａｒｌａｌＮｅｈｒｕＵｎｉｖｅｒｓ...     

2连通无爪图的周长

本文给出p阶2连通无爪图G的周长的下界的新的形式:c(G)≥min{p,2λ-2δ+4},这里λ=min{d(u+d(v)│u,v∈V(G),uv∈E(G)}.     

用Weyl坐标描述Kerr—NUT时空

用 Weyl 坐标可描述全部 Kerr-NUT 时空,根据 Weyl 坐标与 Boyer-Linquist 坐标之 .间的变换,得到了用 Boyer-Linquist 坐标描述的全部 Kerr-NUT 时空。     

Alterations of free amino acids concentrations in cat brain induced by rapid eye movement sleep deprivation

Résumé La concentration de certains acides aminés libres au niveau du cerveau chez le chat change sous l'influence de la privation élective du sommeil paradoxal. Ces changements pourraient s'expliquer par l'augmentation d'excitabilité nerveuse associée à la privation élective du sommeil paradoxal.     

Chromosome 6q25 is linked to susceptibility to leprosy in a Vietnamese population

Leprosy, a chronic infectious disease caused by Mycobacterium leprae, affects an estimated 700,000 persons each year. Clinically, leprosy can be categorized as paucibacillary or multibacillary disease. These clinical forms develop in persons that are intrinsically susceptible to leprosy per se, that is, leprosy independent of its specific clinical manifestation. We report here on a genome-wide search for loci controlling susceptibility to leprosy per se in a panel of 86 families including 205 siblings affected with leprosy from Southern Vietnam. Using model-free linkage analysis, we found significant evidence for a susceptibility gene on chromosome region 6q25 (maximum likelihood binomial (MLB) lod score 4.31; P = 5 x 10(-6)). We confirmed this by family-based association analysis in an independent panel of 208 Vietnamese leprosy simplex families. Of seven microsatellite markers underlying the linkage peak, alleles of two markers (D6S1035 and D6S305) showed strong evidence for association with leprosy (P = 6.7 x 10(-4) and P = 5.9 x 10(-5), respectively).     

A gene expression map of human chromosome 21 orthologues in the mouse

The DNA sequence of human chromosome 21 (HSA21) has opened the route for a systematic molecular characterization of all of its genes. Trisomy 21 is associated with Down's syndrome, the most common genetic cause of mental retardation in humans. The phenotype includes various organ dysmorphies, stereotypic craniofacial anomalies and brain malformations. Molecular analysis of congenital aneuploidies poses a particular challenge because the aneuploid region contains many protein-coding genes whose function is unknown. One essential step towards understanding their function is to analyse mRNA expression patterns at key stages of organism development. Seminal works in flies, frogs and mice showed that genes whose expression is restricted spatially and/or temporally are often linked with specific ontogenic processes. Here we describe expression profiles of mouse orthologues to HSA21 genes by a combination of large-scale mRNA in situ hybridization at critical stages of embryonic and brain development and in silico (computed) mining of expressed sequence tags. This chromosome-scale expression annotation associates many of the genes tested with a potential biological role and suggests candidates for the pathogenesis of Down's syndrome.     

电子技术实验教学模式的探讨

从电子技术实验教学改革的必要性出发,强调了实验教学改革实践中要着重培养学生的创新精神和实践能力,并就电子技术实验教学的改革做了一些有益的探讨.     

Xenorhabdus nematophilus BP品系杀虫毒素基因的克隆与鉴别

构建了昆虫病原线虫共生菌Xenorhabdus nematophilus BP品系的粘粒文库并用生物测定的方法从中筛选到2个对棉铃虫初孵幼虫有口服抑杀作用的克隆cos83和cos76。为初步确定这两个克隆的毒素基因与已报道基因的差异程度，根据已发表的共生菌毒素基因序列资料设计了7对引物对这两个克隆进行PCR扩增并对扩增产物进行测序和分析。从毒力较强的cos83中，7对引物均扩增出与目标片段大小一致的产物，而从cos76中只有5对扩增到目标片段。测序结果显示，cos76的5个PCR扩增产物与cos83的对应扩增产物DAN序列同源性为100％。以cos83的7个PCR扩增产物所编码氨基酸序列进行BLAST分析，它们与X．nematophilus PMF1296和Photorhabdus luminencenc W14毒素相应区间的平均同源性分别为94％和58％，说明cos83毒素是共生菌口服毒素家族的一员但与同类的其它毒素有一定的差异，值得对其杀虫谱，作用机理等进行进一步的研究。     

Paleomagnetic result of the Cenozoic volcanic rocks from the Tuoyun Basin, southwest Tien Shan of China and its tectonic implications

In the present decades, lots of Mesozoic and Ceno-zoic paleomagnetic data have been obtained from westernChina and adjacent areas[1—19], however, these results are still not enough to reconstruct a postcollisional kinematic model for each block of the Tibetan Plateau and Central Asia. As a result, it is very difficult to paleomagnetically depict the postcollisional interaction within blocks of Ti- bet and Central Asia in detail. On the other hand, shal- lower inclinations have been repeat…