Role of 1,25-dihydroxyvitamin D3 in the generation of the acute-phase response in rats with talc-induced granulomatosis

Subcutaneous injection of nonspecific irritants such as magnesium silicate (talc) provokes granulomatous inflammation in the rat. Part of the acute phase response (APR) in these animals is the loss of trabecular bone at sites distant from the site of inflammation. To assess the possible involvement of vitamin D in the bone loss, we studied the development of the acute phase response in vitamin D-deprived rats. The serum APR provoked by subcutaneous inflammation in rachitic rats consisted of hypozincemia, hypercupremia, increased, alkaline phosphatase activity and adrenocorticotropic hormone (ACTH) concentration, and was similar to that in control animals except for the absence of hypoferremia. Control rats with talc-induced subcutaneous inflammation also had splenomegaly and decreased total and mononuclear peripheral blood cell counts, while subcutaneous inflammation did not induce spleen changes in rachitic rats. Subcutaneous inflammation induced the loss of trabecular bone and decreased the osteoblastic cell count in tibial metaphyses in control animals. Rachitic rats had abundant osteoid on trabecular surfaces, and the number of osteoblasts and osteoclasts was comparable to that of the controls. Subcutaneous inflammation did not affect any of the bone parameters in rachitic rats. These results indicate that vitamin D plays an important role in the generation of the acute phase response during inflammation, particularly in the induction of spleen and bone cell changes. The discrepancy of the blood on one hand and bone and spleen indices of the APR on the other, indicate that there may be divergent pathways in the generation of the inflammatory response, some of which may be dependent on vitamin D.     

具有周围组织的动脉脉搏波分析

本文提出在周围结缔组织深处动脉的理论模型。利用土力学原理分析动脉纵向振动,指出动脉纵向振动引起周围结缔组织的位移是以表面波形式传播的,动脉纵向波速是表面波相速度,表面波的存在是动脉纵向振动的必要条件。Lamb波速是本文结论特例。     

基于鲁棒输入训练神经网络的非线性多传感器故障诊断方法及其应用

针对非线性系统多传感器故障诊断时出现的检测准确性下降和数据重构产生的残差污染问题,提出了基于鲁棒输入训练神经网络非线性多传感器故障诊断模型.在目标函数中引入影响因子函数和可靠性系数,并通过计算机模拟和仿真确定最佳影响因子函数形式,抑制了多个含有显著误差故障数据的不良影响,并增加了具备高可靠性的重要数据影响权重,大大减小...     

尿素、碳酸氢铵/添加剂同时脱硫脱硝试验研究

在鼓泡反应装置上进行了尿素、碳酸氢铵/三乙醇胺溶液同时脱硫脱硝的试验研究,比较尿素和碳酸氢铵的脱硫脱硝性能,试验分别对液位、吸收剂组成以及SO2体积分数等参数对脱硝效率的影响规律进行了研究.结果表明:液位、吸收液中尿素/碳酸氢铵的比例及SO2入口浓度对NOx的脱除效率均有重要的影响,液位在459 mm时2种吸收液的脱硝...     

藏雪鸡（Tetraogallus tibetanus）冬季活动规律及觅食地的选择

2009年12月～2010年3月间在西藏日喀则南木林县南木林镇岗噶村周围对藏雪鸡的冬季活动规律与觅食地选择进行了初步研究。结果显示,藏雪鸡在该地区冬季主要活动在平均海拔4484.16±242.99m（n=73）,上线海拔达到5233m,下线海拔4213m。日活动强度显示有3个峰点,分别是9：00、12：00、19：00。主要以6～10只为集群的形式觅食。通过对73个样方14个参数进行主成分分析后发现,海拔高度是冬季藏雪鸡活动规律及觅食地选择的最主要因子,植被是次主要因子,坡向是次要因子。     

Effect of storage conditions on long-term stability of Ag nanoparticles formed via green synthesis

Spherical Ag nanoparticles (AgNPs) with a diameter of 20 nm or smaller were biologically synthesized using algae Parachlorella kessleri. The effect of storage conditions on the long-term stability of AgNPs was investigated. UV/Vis spectrophotometry, transmission electron microscopy, and dynamic light scattering measurements revealed that the long-term stability of AgNPs was influenced by light and temperature conditions. The most significant loss of stability was observed for the AgNPs stored in daylight at room temperature. The AgNPs stored under these conditions began to lose their stability after approximately 30 d; after 100 d, a substantial amount of agglomerated particles settled to the bottom of the Erlenmeyer flask. The AgNPs stored in the dark at room temperature exhibited better long-term stability. Weak particle agglomeration began at approximately the 100th day. The AgNPs stored in the dark at about 5℃ exhibited the best long-term stability; the AgNPs stored under such conditions remained spherical, with a narrow size distribution, and stable (no agglomeration) even after 6 months. Zeta-potential measurements confirmed better dispersity and stability of AgNPs stored under these conditions.     

Low-cost solid FeS lubricant as a possible alternative to MoS2 for producing Fe-based friction materials

Three reaction systems of MoS2–Fe, FeS–Fe, and FeS–Fe–Mo were designed to investigate the use of FeS as an alternative to MoS2 for producing Fe-based friction materials. Samples were prepared by powder metallurgy, and their phase compositions, micro-structures, mechanical properties, and friction performance were characterized. The results showed that MoS2 reacts with the matrix to produce iron-sulfides and Mo when sintered at 1050°C. Iron-sulfides produced in the MoS2–Fe system were distributed uniformly and continuously in the matrix, leading to optimal mechanical properties and the lowest coefficient of friction among the systems studied. The lubricity observed was hypothesized to originate from the iron-sulfides produced. The FeS–Fe–Mo system showed a phase composition, porosity, and density similar to those of the MoS2–Fe system, but an uneven distribution of iron-sulfides and Mo in this system resulted in less-optimal mechanical properties. Finally, the FeS–Fe system showed the poorest mechanical properties among the systems studied because of the lack of Mo reinforcement. In friction tests, the formation of a sulfide layer contributed to a decrease in coefficient of fric-tion (COF) in all of the samples.     

城乡融合背景下特色小镇的发展模式与提升策略

推动城乡融合作为乡村振兴战略背景下的关键举措,要落实这一举措就必须借助有力的载体来破解城乡二元结构的体制机制障碍.而特色小镇作为一种新型的社会组织形态,其不仅对于经济结构的转型具有较强带动作用,也是推动城乡融合发展的重要载体.但就目前特色小镇的发展模式来看,在市场定位、规划布局、特色产业发展、人才引进、基础设施以及投融资方面均存在诸多问题,使其在城乡融合发展过程中的应然功能未得到完全发挥.因此,有必要针对特色小镇在探索发展过程中所存问题来提出相应的完善策略,具体包括找准市场定位、突出特色产业、科学合理规划、重视人才效应、改善基础设施以及扩宽融资渠道,最终促进特色小镇在城乡融合过程中应然功能的发挥.     

量子云计算理论与应用简述

经典计算机在处理大规模数据集或是高强度计算的时候,受硬件工艺与算法原理限制存在性能瓶颈。为了解决此类问题,人们构想出了用量子计算机通过量子力学的微观性质进行计算。近年来实验技术上的突破使得一些科技公司推出了面向公众的量子计算机,以更深刻地理解量子算法并解决一些实际问题。文章介绍了量子云计算的基本原理和发展现状,并给出了量子云计算应用的成功案例,希望以此引起人们对此领域的关注。