Identification and characterization of new functional truncated variants of somatostatin receptor subtype 5 in rodents

Somatostatin and cortistatin exert multiple biological actions through five receptors (sst1-5); however, not all their effects can be explained by activation of sst1-5. Indeed, we recently identified novel truncated but functional human sst5-variants, present in normal and tumoral tissues. In this study, we identified and characterized three novel truncated sst5 variants in mice and one in rats displaying different numbers of transmembrane-domains [TMD; sst5TMD4, sst5TMD2, sst5TMD1 (mouse-variants) and sst5TMD1 (rat-variant)]. These sst5 variants: (1) are functional to mediate ligand-selective-induced variations in [Ca²⁺]_i and cAMP despite being truncated; (2) display preferential intracellular distribution; (3) mostly share full-length sst5 tissue distribution, but exhibit unique differences; (4) are differentially regulated by changes in hormonal/metabolic environment in a tissue- (e.g., central vs. systemic) and ligand-dependent manner. Altogether, our results demonstrate the existence of new truncated sst5-variants with unique ligand-selective signaling properties, which could contribute to further understanding the complex, distinct pathophysiological roles of somatostatin and cortistatin.     

电力输电线路高塔驱鸟系统设计

针对鸟害容易引起电力输电线路事故的问题,设计了一个红外驱鸟报警系统。系统采用被动式热释电红外传感器作为检测部件,进行非接触式远距离检测,并将检测到的微弱电信号转换输出,经被动式热释电红外传感信号处理器BISS0001,进行运算放大、滤波、功率放大,利用所得信号触发报警电路,使鸟受到惊吓飞离杆塔,从而保护输电线路免受鸟害威胁。分析表明,系统具有良好且环保的驱鸟效果。     

Effects of different ant species on the attendance of neighbouring hemipteran colonies and the outcomes for the host plant

Ants commonly participate simultaneously in mutualisms with honeydew-producing hemipterans and extrafloral nectar-bearing host plants. These interactions are based on the exchange of resources (honeydew and extrafloral nectar) for ant protection against natural enemies. The benefits may vary according to the species of ant interacting, and the outcomes for the host plant and hemipteran will depend on the results of the ant-plant-hemipteran relationship as a whole. We studied a plant-mealybug association with Camponotus crassus Mayr (Formicinae) and Ectatomma tuberculatum Olivier (Ectatomminae) in a Brazilian tropical savanna. We aimed to elucidate whether the frequency of visitation by different species of ants can be affected by neighbouring colonies of mealybugs, and whether these ant species influence the number of hemipterans in a different way. Furthermore, we intended to find out whether the interaction between ant and hemipteran has any effect on the proportion of fruit production or on the abundance of trophobiont and non-trophobiont herbivores, also influenced by the ant species. Our results show that neighbouring aggregations of mealybugs influenced the frequency of ant visitation and the ants affected the number of nymphs over time, with both positive results only for C. crassus. We also detected an indirect negative effect on proportion of fruit production and an increase in abundance of trophobiont and non-trophobiont herbivores in the presence of C. crassus-mealybug interaction. Thus, we provide further evidence that colonies of hemipterans interacting with ants can be beneficial for these herbivorous insects, but they are quite harmful to the host plant. Nevertheless, the outcomes can be highly conditional in relation to ant species.     

Distributed Estimation in Sensor Networks with Repetition Coding

This paper considers the distributed estimation of a source parameter using quantized sensor observations in a wireless sensor network with noisy channels. Repetition codes are used to transmit quantization bits of sensor observations and a quasi best linear unbiased estimate is constructed to estimate the source parameter. Simulations show that the estimation scheme achieves a better power and spectral efficiency than the previous scheme.     

高校图书馆自动化、网络化与数据库建设浅议

本文主要论述了高校图书馆自动化系统与数据库建设的内容及系统功能特征,提出了应当注意的问题.     

太行山猕猴蹠骨形态学比较

目的:对太行山猕猴5根蹠骨的非测量形态特征进行描述.方法:对5根猕猴蹠骨的近侧端关节面的形态特征的比较.结果表明:5根蹠骨形态特征显著,通过近侧端关节面的形态比较,可以很容易将5根蹠骨区分.同样根据各个蹠骨近侧端关节面对称性和侧面之间的衔接,可以将每根蹠骨的的侧别区分;但是根据蹠骨形态特征无法区分性别.     

基于对等网络的蠕虫检测系统

针对传统基于互联网的蠕虫检测手段并不完全适应对等网络环境下的蠕虫防御问题,在充分研究现有的网络蠕虫检测技术和综合借鉴当前较为先进的蠕虫检测算法的基础之上,提出了一种基于对等网络的蠕虫检测系统,结合P2P蠕虫的传播特点,从3个层次和多个角度对P2P蠕虫进行快速检测,多重防御,及时预警并尽可能地降低预警的误报率和漏报率,本系统能为后续的蠕虫防御提供一定的参考.     

智能规划的逻辑编码求解性能分析

将SAT问题的编码和求解过程联合起来进行研究,提出了逻辑编码求解性能分析模型,利用该模型对国际标准规划域Logistic域和Blocks World域中的问题进行实验研究,并对实验结果中大量数据进行分析,进而分析逻辑编码的特性与求解效率的关系.实验结果表明逻辑编码的编码方式、编码规模以及规划图的扩展程度影响逻辑编码的求解效率.     

我国高等院校实践教学质量评估体系构建

构建高等院校实践教学质量评估体系是我国极其重要而又紧迫的现实课题。对于实践教学质量评估而言,理清评估目标、评估标准以及评估方法三个关键性环节,有助于把握整个评估系统的脉络。评估目标的制定要参考企业、政府等利益主体的需求等因素,评估标准体系的形成应以国内或国际工程专业认证体系作为前提和参考依据,评估方法要多样化,充分发挥师生的主体能动性,并与教学进程相结合,形成一个良性的反馈系统,最终构建一套实践教学质量评估生态系统。     

基于小波变换的按摩手法肌电信号分析

为通过滚法的量化结果分析为按摩手法的评定及训练提供一定的参考依据, 利用表面肌电仪采集按摩师及初学者滚法相关肌群的表面肌电信号, 采用小波变换算法对信号进行多分辨率分析, 进而研究其能量分布。实验结果表明, 在滚法操作中, 按摩师75%的能量集中在低频段, 其中肱桡肌的能量占总能量的40%, 而初学者能量分布与之有显著差异。在掌握正确的操作要领前提下, 初学者应注重肱桡肌能量的训练。