基于HLA的通用分布式仿真环境研究

HLA正逐步成为我军下一代分布式仿真的基础体系结构，各种基于HLA的仿真对象／模型以及不同版本的RTI也正在积极开发中。论文分析研究了不同版本RTI之间的互连互通、仿真对象的平台独立性与语言无关性、不同仿真对象之间的互操作性、仿真对象的可重用性以及开发仿真对象的复杂度等问题，并针对上述问题，研究了结合WWW技术，设计一个通用分布式仿真环境GDSE的可行性，并提出一个初步的设计方案。     

流体动力相似理论在旋流器中的建模

通过流体动力相似理论建立旋流器的结构参数、操作参数及物料的物性参数对其分离性能的影响的定性模型,在此基础上可通过一系列单因素试验作线性回归处理,从而得到旋流器进口欧拉准数,底流分率及分离性能的定量数学模型。     

K-rich lamellar exsolution in clinopyroxene： Constraint on the depth of peridotite source at Zhimafang

The oriented lamellar K-rich exsolutions within clinopyroxene host were recognized in garnet peridotite massif at Zhimafang in the Sulu ultrahigh pressure metamorphic terrane, eastern China. EMP and TEM analyses revealed that the composition and the index of electron diffraction for this exsolution are corresponding with phlogopite, and the shape is the lamellae with 1 μm in width and 5 to 30 μm in length. Moreover, the topotaxy is that the (001) of K-rich exsolution parallels to (I00) of the clinopyroxene host. The electron diffraction analyzing shows the exsolution is of a 1M polymorphism. The high-resolution lattice fringe image displays the stack features along [001], which only a layer mineral shows. We conclude that the clinopyroxene with IM and K-rich exsolution was probably derived from mantle depths over 240 km, thus resulting from decompressional exsolution in the initial stage of slab exhumation.     

From mRNA to tumor suppressor

The combination of inhibition of RNA degradation and comparative genomic scanning is a powerful new method for detecting gene disruptions. The utility of the method is well-illustrated by a series of observations linking the ephrin receptor EPHB2 to prostate cancer.     

浅谈“问题解决“教学

问题解决自提出以来就受到数学教育界的普遍关注。本文简述了“问题解决“教学的意义,着重从问题解决的影响因素出发阐述如何进行有效的“问题解决“教学,并指出了“问题提出“的重要性。     

A flower image retrieval method based on ROI feature

Flower image retrieval is a very important step for computer-aided plant species recognition. In this paper, we propose an efficient segmentation method based on color clustering and domain knowledge to extract flower regions from flower images. For flower retrieval, we use the color histogram of a flower region to characterize the color features of flower and two shape-based features sets, Centroid-Contour Distance (CCD) and Angle Code Histogram (ACH), to characterize the shape features of a flower contour. Experimental results showed that our flower region extraction method based on color clustering and domain knowledge can produce accurate flower regions. Flower retrieval results on a database of 885 flower images collected from 14 plant species showed that our Region-of-Interest (ROI) based retrieval approach using both color and shape features can perform better than a method based on the global color histogram proposed by Swain and Ballard (1991) and a method based on domain knowledge-driven segmentation and color names proposed by Das et al.(1999).     

Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms

Subcellular localization of nitric oxide (NO) synthases with effector molecules is an important regulatory mechanism for NO signalling. In the heart, NO inhibits L-type Ca2+ channels but stimulates sarcoplasmic reticulum (SR) Ca2+ release, leading to variable effects on myocardial contractility. Here we show that spatial confinement of specific NO synthase isoforms regulates this process. Endothelial NO synthase (NOS3) localizes to caveolae, where compartmentalization with beta-adrenergic receptors and L-type Ca2+ channels allows NO to inhibit beta-adrenergic-induced inotropy. Neuronal NO synthase (NOS1), however, is targeted to cardiac SR. NO stimulation of SR Ca2+ release via the ryanodine receptor (RyR) in vitro, suggests that NOS1 has an opposite, facilitative effect on contractility. We demonstrate that NOS1-deficient mice have suppressed inotropic response, whereas NOS3-deficient mice have enhanced contractility, owing to corresponding changes in SR Ca2+ release. Both NOS1-/- and NOS3-/- mice develop age-related hypertrophy, although only NOS3-/- mice are hypertensive. NOS1/3-/- double knockout mice have suppressed beta-adrenergic responses and an additive phenotype of marked ventricular remodelling. Thus, NOS1 and NOS3 mediate independent, and in some cases opposite, effects on cardiac structure and function.     

禀经酌伟 弥纶一代－《中国现代寓言史纲》读后

《中国现代寓言史纲》是陈蒲清先生《中国古代寓言史》的续篇,是又一部填补空白 的著作。他的问世,不仅完成了他中国寓言史的宏大建构,而且,通过对我国现代寓言史的全面、深入地探究、总结,将会极大地推动我国当代的寓言研究与寓言创作向前发展。