Role of the Raphe Magnus nucleus in morphine analgesia : studies with intracerebral microinjections in the rat]

Microinjections of low concentration of morphine (5 micrograms) into the nucleus Raphé Magnus of the Rat produce a strong analgesia that can be reversed by systemic naloxone, an opiate antagonist. The administration of naloxone (5 micrograms) into the Raphé Magnus considerably reduces the effects of intravenous morphine. The effects of microinjections of morphine are strongly reduced by Cinanserin, suggesting a role for serotoninergic mechanisms in morphine analgesia.     

Adaptation of the pituitary gland to prolonged LRH stimulation

Summary With prolonged constant rate infusion of luteinizing hormone-releasing hormone (LRH), the LH secretion rate of the rat pituitary gland changes continuously until a steady state of relative desensitization has developed. Recovery from this state can occur independently from changes in the pituitary's LH content.     

Action of insulin on the glycogen content of liver and muscle of the murrel,Ophicephalus striatus (Bloch)

Résumé Des doses variées d'insuline administrées à l'Ophicephalus striatus ont augmenté la quantité de glycogène du foie et des muscles. Dans le foie, les doses étant fortes (40 IU et 60 IU), la quantité normale de glycogène a presque quadruplé et elle a plus que septuplé dans les muscles. Le mécanisme possible présidant à l'action de l'insuline est aussi discuté.