An Ig-A-like substance in the chicken's pineal

Summary Immunohistochemistry revealed an Ig-A-like substance on the luminal surface of the pineal follicles and in the parafollicular layer. This substance was observed around 1 week of age and disappeared by 8 weeks at the time when the transformation of the follicular pattern leads to an adult-type pineal tissue.     

Statecharts for Distributed Product Data Management System Modelling

Product data management (PDM) has been accepted as an important tool for the manufacturing industries. In recent years, more and mor e researches have been conducted in the development of PDM. Their research area s include system design, integration of object-oriented technology, data distri bution, collaborative and distributed manufacturing working environment, secur ity, and web-based integration. However, there are limitations on their rese arches. In particular, they cannot cater for PDM in dis...     

面向WTO完善无形资产会计研究

文章借鉴有关国际贯例与经验，并结合我国实际情况，提出完善目前无形资产计量与核算的方法，并充分发挥无形资产的潜在价值，以不断优化企业财务结构，提高企业竞争能力，为企业国际化经营打下坚实的基础。     

Leaning Towards Agile in 21~(st) Century

Background: During the last fifteen years there ha s been an increased drive for organisations to reduce costs. From a production po int, this has often centred on lean manufacturing and JIT waste elimination proc esses. However, in 1991, the Iaccocca Institute Bethlehem P.A commissioned a re port specifically to analyse the changing nature of the marketplace. As a result , in the following year, the Agile Manufacturing Forum was initiated and the ter m ‘agile or responsive manufacturing‘ was first intr...     

排球运动中的供能特点与营养补充

物质和能量代谢是人体各组织器官机能活动的基础，应用运动时物质和能量代谢规律指导训练期间的营养安排是非常有益的．通过对排球运动的特点进行分析，结合各供能系统的特点以及各种能量物质分解的先后关系，简要陈述排球比赛中的物质和能量代谢，分析了排球运动中疲劳产生的可能原因，有针对性地提出训练中的营养安排以及应当注意补充的几种营养物质。     

Intramammary expression and therapeutic effect of a human lysozyme-expressing vector for treating bovine mastitis

To develop a gene therapy strategy for treating bovine mastitis, a new mammary-specific vector containing human lysozyme (hLYZ) cDNA and kanamycin resistance gene was constructed for intramammary expression and clinical studies. After one time acupuncture or intracisternal infusion of healthy cows with 400 μg of the p215C3LYZ vector, over 2.0 μg/ml of rhLYZ could be detected by enzymatic assay for about 3 weeks in the milk samples. Western blotting showed that rhLYZ secreted into milk samples from the vector-injected cows had molecular weight similar to that of the natural hLYZ in human colostrums. Twenty days after the primary injection, the quarters were re-injected with the same vector by quarter acupuncture and even higher concentrations of rhLYZ could be detected. Indirect competitive ELISA of milk samples showed that the vector injection did not induce detectable humoral immune response against hLYZ. Clinical studies showed that twice acupuncture of quarters with the p215C3LYZ vector had overt therapeutic effect on clinical and subclinical mastitis previously treated with antibiotics, including disappearance of clinical symptoms and relatively high microbiological cure rates. These data provide a solid rationale for using the vector to develop gene therapy for treating bovine mastitis.     

FBE复合覆盖层天然气管道外防腐施工实践

简述了天然气集输设施腐蚀的危害。结合工程实践。介绍了FBE复合覆盖层天然气管道外防腐施工方法及施工工艺，从防腐材料的选择、施工环境温度的控制、涂料的配制等方面对施工技术措施及质量控制要点进行了重点阐述。     

心理治疗还是药物治疗

心理治疗与药物治疗是精神病领域的两种治疗模式。心理治疗模式认为，个体精神状况正常与否主要受情绪、人格等心理因素影响，精神疾病由后天环境和生活经历所致；药物治疗模式则认为，精神病及各类神经症都有其生理基础，大脑机能的缺陷是导致精神疾病的主要原因，因此主张用药物进行治疗。尽管两者在精神病治疗中都有自己的优势与不足，但是在科学一统天下的今天，生物学模式似乎成了治疗的主流。要想最终解决心理治疗与药物治疗之争，科学预测精神病治疗的未来及新世纪心理治疗的命运，必须首先解决：（1）心理学的学科体系问题；（2）精神疾病的界定问题以及（3）心身关系问题。     

Aspirin-like drugs may block pain independently of prostaglandin synthesis inhibition

Summary Using flurbiprofen, a chiral anti-inflammatory and analgesic 2-arylpropionic acid derivative, the enantiomers of which are not converted to each other (less than 5%) in rats or man, we obtained evidence that prostaglandin synthesis inhibition is primarily mediating the anti-inflammatory activity but prostaglandin synthesis independent mechanisms contribute to the analgesic effects. Thus, the S-form inhibited prostaglandin synthesis, inflammation and nociception in rats. The R-form had much less effect on prostaglandin synthesis and did not affect inflammation. It did, however, block nociception in rats almost as potently as the S-form. S-flurbiprofen, in contrast to the R-form, was clearly ulcerogenic in the gastrointestinal mucosa. These results indicate additional molecular mechanisms of analgesia and suggest the use of R-arylpropionic acids as analgesics.