Effect of conditioned media on nerve cell differentiation

Summary Glial conditioned medium strongly stimulates the morphological maturation of cultured neuronal cells, while fibroblast and meningeal conditioned media have weaker effects.Acknowledgment. We acknowledge the expert technical assistance of Mrs M.F. Knoetgen.     

Abnormal sensitivity to erythropoietin in the erythroblast precursors in Vaquez disease]

Marrow specimens of patients with polycythemia vera rise to erythrocytic colonies in vitro without addition of erythropoietin to the culture. This behavior was never observed with marrow cells of normal subjects or secondary erythrocytosis. These results indicate that the sensitivity of some erythrocytic progenitor cells to erythropoietin is altered in polycythemia vera.     

Removal of polyethylene glycols from immunoglobulin samples by adsorption chromatography on polystyrene beads

Summary A chromatographic method is described for 80% removal of polyethylene glycol of different types, 600–6000, from human immunoglobulin preparations. Bio-beads SM-2 were used in batch procedures or packed on a 16×100 mm column. The polyethylene glycols were desorbed with 75% ethanol.     

The lambda phage att site: functional limits and interaction with Int protein

Site specific integrative recombination of bacteriophage lambda involves unequal partners. The minimal phage att site is composed of approximately 240-base pairs and four distinct binding sites for Int protein, at least three of which are crucial for function. This 'donor site' recombines efficiently with a smaller 'recipient site' that lacks the extensive interactions with Int protein.     

Dialyzable serum factors alter cellular immunity in pregnancy

Summary Lymphocyte responsiveness was found to be decreased in pregnant and increased in habitually aborting women. This is attributed to a dialyzable serum factor(s), that can be removed from the surface of lymphocytes by repeated washing.     

Effects of thalidomide on the skeleton of the rat foetus

Zusammenfassung Nach Thalidomidverabreichung an trächtigen Ratten fanden wir Fruchtresorption und Anomalien am fünften Brustbeinkern der Föten. Weitere ergänzende Skelettuntersuchungen ergaben, besonders bei mittelgrossen Thalidomidgaben, Verknöcherungs-störungen an den Halswirbelkörpern. Andere Skeletteile zeigten keine Thalidomid-abhängigen Entwicklungsvariationen.     

Survival of embryonic limb bud transplants in snapping turtles

Résumé Des membres furent transplantés chez des tortues embryonnaires deChelydra serpentina en combinaisons allogénique et xénogénique. Ces greffes survivaient longtemps, mais étaient usuellement rejettées de façon chronique.

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Supported by U.S. Public Health Service Grants No. 8 RO1 HD 03484 and No. 1 FO2 AM 33,123 from the National Institutes of Health.     

Effect of biogenic amines on γ-amylase (acid α-glucosidase)

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