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排序方式: 共有225条查询结果,搜索用时 15 毫秒
191.
Crow YJ Leitch A Hayward BE Garner A Parmar R Griffith E Ali M Semple C Aicardi J Babul-Hirji R Baumann C Baxter P Bertini E Chandler KE Chitayat D Cau D Déry C Fazzi E Goizet C King MD Klepper J Lacombe D Lanzi G Lyall H Martínez-Frías ML Mathieu M McKeown C Monier A Oade Y Quarrell OW Rittey CD Rogers RC Sanchis A Stephenson JB Tacke U Till M Tolmie JL Tomlin P Voit T Weschke B Woods CG Lebon P Bonthron DT Ponting CP Jackson AP 《Nature genetics》2006,38(8):910-916
Aicardi-Goutières syndrome (AGS) is an autosomal recessive neurological disorder, the clinical and immunological features of which parallel those of congenital viral infection. Here we define the composition of the human ribonuclease H2 enzyme complex and show that AGS can result from mutations in the genes encoding any one of its three subunits. Our findings demonstrate a role for ribonuclease H in human neurological disease and suggest an unanticipated relationship between ribonuclease H2 and the antiviral immune response that warrants further investigation. 相似文献
192.
Klaus Regenauer-Lieb Andrew Bunger Hui Tong Chua Arcady Dyskin Florian Fusseis Oliver Gaede Rob Jeffrey Ali Karrech Thomas Kohl Jie Liu Vladimir Lyakhovsky Elena Pasternak Robert Podgorney Thomas Poulet Sheik Rahman Christoph Schrank Mike Trefry Manolis Veveakis Bisheng Wu David A. Yuen Florian Wellmann Xi Zhang 《地球科学学刊》2015,(1)
Deep geothermal from the hot crystalline basement has remained an unsolved frontier for the geothermal industry for the past 30 years. This poses the challenge for developing a new un-conventional geom... 相似文献
193.
Marjan Radi Behnam Dezfouli Kamalrulnizam Abu Bakar Shukor Abd Razak Mohammad Ali Nematbakhsh 《清华大学学报》2011,16(5):475-490
The existing multipath routing protocols for wireless sensor networks demonstrate the efficacy of traffic distribution over multiple paths to fulfill the Quality of Service (QoS) requirements of different applications.However,the performance of these protocols is highly affected by the characteristics of the wireless channel and may be even inferior to the performance of single-path approaches.Specifically,when multiple adjacent paths are being used concurrently,the broadcast nature of wireless channels res... 相似文献
194.
柿产业存在的问题及发展对策 总被引:1,自引:0,他引:1
柿树是我国主栽果树种类之一,栽培历史悠久.从柿子品种资源丰富,栽培管理容易,市场需求大和产品品种多样等方面分析了我国发展柿产业的优势.通过对我国柿树生产、保鲜加工技术和营销方面所存在问题的研究,提出发展柿产业相应的对策:1)调整品种结构,培育和引进优良品种,普及栽培技术;2)加强柿贮藏保鲜和加工技术的研究;3)合理布局,发挥地域优势,发展特色产业链;4)建立服务体系,完善营销渠道. 相似文献
195.
Ahmat Ali Ruxangul Jamal Weiwei shao Adalet Rahman Yakupjan Osman Tursun Abdiryim 《自然科学进展(英文版)》2013,23(6):524-531
Poly(3,4-propylenedioxythiophene)/nano-Zinic Oxide(PProDOT/ZnO) composites with the content of 3-7 wt%nano-ZnO were synthesized by the solid-state method with FeCl3 as oxidant.The structure and morphology of the composites were characterized by Fourier transform infrared(FTIR)spectroscopy,ultraviolet-visible(UV-vis) absorption spectroscopy,X-ray diffraction(XRD) and transmission electron microscopy(TEM).The electrochemical performances of the composites were investigated by galvanostatic charge-discharge,cyclic voltammetry and electrochemical impedance spectroscopy(EIS).The photocatalytic activities of the composites were investigated by the degradation of methylene blue(MB) dyes in aqueous medium under UV light irradiation.The results from FTIR and UV-vis spectra showed that the PProDOT/ZnO composites were successfully synthesized by solid-state method,and nano-ZnO had great influences on the conjugation length and oxidation degree of the polymers.Furthermore,the PProDOT/5 wt%ZnO had the highest conjugation and oxidation degree among the composites.The results of XRD analysis indicated that there were some FeCl4- ions as doping agent in the PProDOT matrix,and the content of ZnO had no effect on diffraction pattern of PProDOT.Morphological studies revealed that the pure PProDOT and composites had similar morphological structure,and all the composites displayed an irregular sponge like morphology.The results of electrochemical tests showed that the PProDOT/5 wt%ZnO had a higher electrochemical activity with a specific capacitance value of 220 F g-1 than others.The results from photocatalytic activities of the composites indicated that the PProDOT/5 wt%ZnO had better photocatalytic activity than other composites. 相似文献
196.
James M.TIEN Ananth KRISHNAMURTHY Ali YASAR Department of Decision Sciences Engineering Systems Rensselaer Polytechnic Institute Eighth St.Troy New York USA 《系统科学与系统工程学报(英文版)》2004,13(3):257-278
Our focus herein is on developing an effective taxonomy for the simultaneous and real-timemanagement of supply and demand chains.More specifically,the taxonomy is developed in terms ofits underpinning components and its research foci.From a components perspective,we first considerthe value chain of supplier,manufacturer,assembler,retailer,and customer,and then develop aconsistent set of definitions for supply and demand chains based on the location of the customer orderpenetration point.From a research perspective,we classify the methods that are employed in themanagement of these chains,based on whether supply and/or demand are flexible or fixed.Interestingly,our taxonomy highlights a very critical research area at which both supply and demandare flexible,thus manageable.Simultaneous management of supply and demand chains sets the stagefor mass customization which is concerned with meeting the needs of an individualized customermarket.Simultaneous and real-time management of supply and demand chains set 相似文献
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199.
Effects of different friction stir welding conditions on the microstructure and mechanical properties of copper plates
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Friction stir welding is a new and innovative welding method used to fuse materials. In this welding method, the heat generated by friction and plastic flow causes significant changes in the microstructure of the material, which leads to local changes in the mechanical properties of the weld. In this study, the effects of various welding parameters such as the rotational and traverse speeds of the tool on the microstructural and mechanical properties of copper plates were investigated; additionally, Charpy tests were performed on copper plates for the first time. Also, the effect of the number of welding passes on the aforementioned properties has not been investigated in previous studies. The results indicated that better welds with superior properties are produced when less heat is transferred to the workpiece during the welding process. It was also found that although the properties of the stir zone improved with an increasing number of weld passes, the properties of its weakest zone, the heat-affected zone, deteriorated. 相似文献
200.
针对天体光谱,通过小波包分解对光谱特征进行提取,并将该特征与支撑矢量机相结合,从而得到一种对活动天体与非活动天体实现自动分类的新方法.该方法未用到谱线信息,避免了谱线提取的复杂过程,使得在低信噪比,红移未知的情况下,依然能够对活动天体与非活动天体进行有效的分类识别.通过实验表明,该方法比其他现有方法有更高的识别率,可达到96.64%,并具有相当好的鲁棒性. 相似文献