Effect of alcohol ingestion on the epithelial cell population in rat small intestine

Summary Chronic administration of alcohol to well-nourished rats led to striking changes in the small intestinal cell population. The present experiments corroborate the view that alcohol is directly toxic to the small intestine.The authors wish to thank Mr.P. R. Gaspar for the technical assistance.     

Delay of normal development of sea urchin embryos by cytosine arabinoside

Résumé Le développement des ufs d'oursins est ralenti par la cytosine arabinoside à laquelle on les expose pendant 4 à 8 h, mais il reprend son cours après le traitement.

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This research was performed at the Naples Zoological Station in August of 1965 and was supported by an American Table award from the American Institute of Biological Sciences. I wish to thank Dr.A. Orengo for his kind assistance during my stay at the Station and to the director,P. Dohrn, for his hospitality.     

Kinetics of insulin secretion in response to glucose by isolated islands of Langerhans from the fetal rat]

Isolated islets of Langerhans from 21.5 day-old foetal Rats were studied in a perifusion system in vitro. The overall dynamics of insulin release by the foetal islets in response to glucose 13.9 mM is biphasic and qualitatively similar to that obtained with islets of adult Rats. The magnitude of the initial phase of insulin secretion is similar for the foetal and adult islets. The second phase is fourfold higher in the adult than in the foetus. The response of foetal islets occurs, 45 to 60 sec. after the increase of glucose concentration in the medium and a maximum insulin release for the first phase is obtained with a lag period of 2 min. The difference between foetal and adult islets is essentially quantitative.     

Phospholipid composition ofDipylidium caninum

Summary The phospholipid composition ofDipylidium caninum has been studied. Chloroform-methanol-soluble fraction amounted to 2.4% and phospholipids to 0.5% of the wet weight of the parasite. Phosphatidyl choline and phosphatidyl ethanolamine represented the bulk of the phospholipids, whereas phosphatidyl serine, phosphatidyl inositol, lysolecithin and lysophosphatidyl ethanolamine were present in minor amounts. Sulfatides were also identified in this parasite.