Effect of ions on the light-sensitive current in retinal rods

The effect of ions on the light-sensitive current of retinal rods was studied by sucking the inner segment into a tightly fitting capillary with the outer segment projecting into a flowing solution. This new method showed that the light-sensitive pathway, in which Na+ is the normal carrier of current, has an ionic selectivity different from that of other known sodium channels. Externàl calcium has a striking effect on the current, which increased about 20-fold when all calcium was removed. Reducing the sodium concentration gradient greatly prolonged the response to a flash of light, as would be expected if internal calcium blocks sodium channels and if light releases calcium which is subsequently extruded by a sodium-calcium exchange mechanism.     

The effect of lipids fromListeria monocytogenes on immune response in mice

Résumé Nos expériences ont démontré que les lipides deListeria monocytogenes ont un fort effet adjuvant aux niveaux cellulaire et humoral. Comme antigène, on a utilisé des èrythrocytes de mouton. On a déterminé le nombre de cellules de la rate produisant des anticorps ainsi que le titre de l'hémolysine d'après la méthode de l'hémolyse radiale en gélose.

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Supported by grants from Polish Academy of Science.     

Action diurétique et natriurique du Chlorpropamide chez le Rat. Comparaison avec le Tolbutamide

Zusammenfassung Sulfonylharnstoffderivate wirken bei der mit Wasser belasteten Ratte wie ein Salidiureticum. Dieser Wirkungsmodus ist der Grund weshalb diese Pharmaka wie Salidiuretica bei Diabetes insipidus günstig wirken.