排序方式: 共有152条查询结果,搜索用时 15 毫秒
91.
属性相似度的准确性是影响实体分辨准确程度的重要因素之一.为提高属性相似度的准确性,分析了属性相似度与函数依赖的关系,给出了属性相似度调整原则,提出了依据函数依赖进行相似度划分、相似度传递调整和计算相似度调整代价的方法,提出了通过属性相似度调整提高属性相似度准确性的属性相似度传递调整算法.实验结果表明,该算法能够更好地区分匹配记录对和不匹配记录对,获得更高的查全率、查准率和F1值. 相似文献
92.
Arking DE Pfeufer A Post W Kao WH Newton-Cheh C Ikeda M West K Kashuk C Akyol M Perz S Jalilzadeh S Illig T Gieger C Guo CY Larson MG Wichmann HE Marbán E O'Donnell CJ Hirschhorn JN Kääb S Spooner PM Meitinger T Chakravarti A 《Nature genetics》2006,38(6):644-651
Extremes of the electrocardiographic QT interval, a measure of cardiac repolarization, are associated with increased cardiovascular mortality. We identified a common genetic variant influencing this quantitative trait through a genome-wide association study on 200 subjects at the extremes of a population-based QT interval distribution of 3,966 subjects from the KORA cohort in Germany, with follow-up screening of selected markers in the remainder of the cohort. We validated statistically significant findings in two independent samples of 2,646 subjects from Germany and 1,805 subjects from the US Framingham Heart Study. This genome-wide study identified NOS1AP (CAPON), a regulator of neuronal nitric oxide synthase, as a new target that modulates cardiac repolarization. Approximately 60% of subjects of European ancestry carry at least one minor allele of the NOS1AP genetic variant, which explains up to 1.5% of QT interval variation. 相似文献
93.
提出了一种基于伯努利(Bernoulli)多项式的分数阶微分方程数值求解的新方法,推导了分数导数的Bernoulli运算矩阵,结合Tau法和配方法将分数阶微分方程简化为代数方程组。通过实例说明了该方法的有效性和适用性。 相似文献
94.
Analysis of a RanGTP-regulated gradient in mitotic somatic cells 总被引:1,自引:0,他引:1
The RanGTPase cycle provides directionality to nucleocytoplasmic transport, regulating interactions between cargoes and nuclear transport receptors of the importin-beta family. The Ran-importin-beta system also functions in mitotic spindle assembly and nuclear pore and nuclear envelope formation. The common principle underlying these diverse functions throughout the cell cycle is thought to be anisotropy of the distribution of RanGTP (the RanGTP gradient), driven by the chromatin-associated guanine nucleotide exchange factor RCC1 (refs 1, 4, 5). However, the existence and function of a RanGTP gradient during mitosis in cells is unclear. Here we examine the Ran-importin-beta system in cells by conventional and fluorescence lifetime microscopy using a biosensor, termed Rango, that increases its fluorescence resonance energy transfer signal when released from importin-beta by RanGTP. Rango is predominantly free in mitotic cells, but is further liberated around mitotic chromatin. In vitro experiments and modelling show that this localized increase of free cargoes corresponds to changes in RanGTP concentration sufficient to stabilize microtubules in extracts. In cells, the Ran-importin-beta-cargo gradient kinetically promotes spindle formation but is largely dispensable once the spindle has been established. Consistent with previous reports, we observe that the Ran system also affects spindle pole formation and chromosome congression in vivo. Our results demonstrate that conserved Ran-regulated pathways are involved in multiple, parallel processes required for spindle function, but that their relative contribution differs in chromatin- versus centrosome/kinetochore-driven spindle assembly systems. 相似文献
95.
Contrasting patterns of early twenty-first-century glacier mass change in the Himalayas 总被引:9,自引:0,他引:9
Glaciers are among the best indicators of terrestrial climate variability, contribute importantly to water resources in many mountainous regions and are a major contributor to global sea level rise. In the Hindu Kush-Karakoram-Himalaya region (HKKH), a paucity of appropriate glacier data has prevented a comprehensive assessment of current regional mass balance. There is, however, indirect evidence of a complex pattern of glacial responses in reaction to heterogeneous climate change signals. Here we use satellite laser altimetry and a global elevation model to show widespread glacier wastage in the eastern, central and south-western parts of the HKKH during 2003-08. Maximal regional thinning rates were 0.66?±?0.09 metres per year in the Jammu-Kashmir region. Conversely, in the Karakoram, glaciers thinned only slightly by a few centimetres per year. Contrary to expectations, regionally averaged thinning rates under debris-mantled ice were similar to those of clean ice despite insulation by debris covers. The 2003-08 specific mass balance for our entire HKKH study region was -0.21?±?0.05?m?yr(-1) water equivalent, significantly less negative than the estimated global average for glaciers and ice caps. This difference is mainly an effect of the balanced glacier mass budget in the Karakoram. The HKKH sea level contribution amounts to one per cent of the present-day sea level rise. Our 2003-08 mass budget of -12.8?±?3.5 gigatonnes (Gt) per year is more negative than recent satellite-gravimetry-based estimates of -5?±?3?Gt?yr(-1) over 2003-10 (ref. 12). For the mountain catchments of the Indus and Ganges basins, the glacier imbalance contributed about 3.5% and about 2.0%, respectively, to the annual average river discharge, and up to 10% for the Upper Indus basin. 相似文献
96.
以光纤传像束为基础搭建激光焊金属蒸气的多角度同步成像平台,从平台的3个方向获取金属蒸气的二维投影图像,并以二维投影图像为基础,采用基于中心投影模型的代数迭代法进行金属蒸气图像的三维重建,以获得金属蒸气图像辐射亮度的三维分布.结果表明:对于高功率激光焊接而言,金属蒸气图像的辐射亮度呈现出由内到外而逐渐降低的变化趋势,其中心部分的辐射亮度分布并不连续,且存在相对孤立的离散区域;当匙孔的开口与激光入射点重合时,金属蒸气的尺寸较小且贴近于工件表面;当熔池波动而造成匙孔失稳时,金属蒸气图像出现了形态异常和较为显著的尺寸变化. 相似文献
97.
针对典型交通场景下智能车多车协作的实时性、可靠性及分布式协作的要求,提出了基于可靠预约ALOHA的介质访问层信道接入协议,通过使用动态时分复用信道而提高车间通信的实时性,用预约时隙和广播机制而提高通信的可靠性与分布式特性,并设计了针对车队和超车的多车协作算法.同时,通过实验验证了通信协议及系统的可行性与可靠性. 相似文献
98.
1 IntroductionIn the Bayesian game modeIs[1t2], the uncertainty of objectives is described with probability. But sometbe the uncertainty in practice i8 gben by some fuzzy parnders, and theobjectives of players mny not be to mallmize the expected payOffs[3'4'5j. [6,7l discussed themodeIs for endogenous Stackelberg and price leadership under complete infOmation. In [8,9],we studied the Cournot and Stackelberg models with fuzzy parameters. In this paPer, we givea new subjective equllibrinm fo… 相似文献
99.
针对手机用户的个性化需求较高及传统方法的进程监控问题, 设计并实现了基于Android 开发平台的手机言行记录系统。该系统通过控制手机通讯录信息、文件加密操作、应用程序监控以及日志监控等方式实时监控分析手机用户的言行记录, 方便用户的自我监控与管理。该方法主要运用Intent 和日志监控实现软件监控功能,通过类FileEncrpter 对文件系统加密, 对录音加密则使用流加密, 运用MediaRecord 类和ACC(Advanced AudioCoding)编码实现音频录制。实验结果表明, 该系统达到了较为理想的实验效果, 证明了该系统的可行性。 相似文献
100.
介绍了列车运行控制系统的基本组成和原理,采用通用ARM芯片S3C2440设计了列车运行控制仿真硬件系统以及包含列车模型的PC端仿真软件.使用串口UART实现下位机控制系统硬件和上位机列车仿真模型软件之间的数据通信.最后,设计了基于滑动模态状态观测器的列车控制算法,并在仿真测试系统中进行了测试. 相似文献