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排序方式: 共有169条查询结果,搜索用时 234 毫秒
71.
Zhang Yong''''an Zhou Di & Duan GuangrenCenter for Control Guidance Harbin Institute of Technology Harbin P. R. China 《系统工程与电子技术(英文版)》2005,16(1)
1.INTRODUCTION TheextendedKalmanfilter(EKF)isthemost widelyusednonlinearfilterbecauseofitssimplicity despiteitsinconsistenceinsomeapplications.Thein consistenceoftheEKFmainlyarisesfromtheuseof linearization.Sincethereferencepointsforthelin earizationarearoundthepriorestimatesofthestate (filteredestimateforlinearizationofstatetransition equationandpredictiveestimateforlinearizationof measurementequation,respectively),agoodprior estimateisveryimportantfortheEKF.Inmanycas es,themeasur… 相似文献
72.
Both α-Co(OH)_2 and Co_3O_4 porous microspheres have been synthesized by the simple solvothermal process as well as subsequent treatment. The morphologies and structures of the as-synthesized products were characterized by X-ray diffraction(XRD), scanning electron microscopy(SEM), transmission electron microscopy(TEM), and X-ray photoelectron spectroscopy(XPS). Both samples have spherical structures consisting of nanosheets, with similar crystallinity. The electrochemical properties of both samples were further investigated. Both samples show excellent electrochemical performances including high specific capacity, good cycling stability and rate capability. All results show that these microspheres exhibit potential applications in energy storage field. 相似文献
73.
The C-banding pattern and nucleolar organizer regions of the metaphase chromosomes of Cynoglossus semilaevis are reported. The interstitial regions in all chromosomes including the pair of sex chromosomes had positive C-bands, and the 6th and 12th pairs of chromosomes were entirely stained in most cases. Some chromosomes such as the 1st, 2nd, 7th, 8th, 9th and 10th pairs showed C-bands at centromeric or distal ends. The C-banding heretochromatin occupies 30.03% of the total chromosome surface in C. semilaevis, which is similar to that of amphibians such as Mixophyes fasciolatus (30. 2% ) and M. schevilli (20. 7% ), but is rather lower than that of cephalochordate Branchiostoma belcheri (54. 3 % ). Silver staining revealed a single pair of nucleolar organizer regions ( NORs) located in the telomeric regions of Chromosome 2. The association of NORs with heterochromatin observed in vertebrates also occurs in C. semilaevis as the telomeric regions of Chromosome 2 are always stained positively with C-banding. 相似文献
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Yusa K Rashid ST Strick-Marchand H Varela I Liu PQ Paschon DE Miranda E Ordóñez A Hannan NR Rouhani FJ Darche S Alexander G Marciniak SJ Fusaki N Hasegawa M Holmes MC Di Santo JP Lomas DA Bradley A Vallier L 《Nature》2011,478(7369):391-394
Human induced pluripotent stem cells (iPSCs) represent a unique opportunity for regenerative medicine because they offer the prospect of generating unlimited quantities of cells for autologous transplantation, with potential application in treatments for a broad range of disorders. However, the use of human iPSCs in the context of genetically inherited human disease will require the correction of disease-causing mutations in a manner that is fully compatible with clinical applications. The methods currently available, such as homologous recombination, lack the necessary efficiency and also leave residual sequences in the targeted genome. Therefore, the development of new approaches to edit the mammalian genome is a prerequisite to delivering the clinical promise of human iPSCs. Here we show that a combination of zinc finger nucleases (ZFNs) and piggyBac technology in human iPSCs can achieve biallelic correction of a point mutation (Glu342Lys) in the α(1)-antitrypsin (A1AT, also known as SERPINA1) gene that is responsible for α(1)-antitrypsin deficiency. Genetic correction of human iPSCs restored the structure and function of A1AT in subsequently derived liver cells in vitro and in vivo. This approach is significantly more efficient than any other gene-targeting technology that is currently available and crucially prevents contamination of the host genome with residual non-human sequences. Our results provide the first proof of principle, to our knowledge, for the potential of combining human iPSCs with genetic correction to generate clinically relevant cells for autologous cell-based therapies. 相似文献
77.
Alföldi J Di Palma F Grabherr M Williams C Kong L Mauceli E Russell P Lowe CB Glor RE Jaffe JD Ray DA Boissinot S Shedlock AM Botka C Castoe TA Colbourne JK Fujita MK Moreno RG ten Hallers BF Haussler D Heger A Heiman D Janes DE Johnson J de Jong PJ Koriabine MY Lara M Novick PA Organ CL Peach SE Poe S Pollock DD de Queiroz K Sanger T Searle S Smith JD Smith Z Swofford R Turner-Maier J Wade J Young S Zadissa A Edwards SV Glenn TC Schneider CJ Losos JB Lander ES Breen M Ponting CP Lindblad-Toh K 《Nature》2011,477(7366):587-591
The evolution of the amniotic egg was one of the great evolutionary innovations in the history of life, freeing vertebrates from an obligatory connection to water and thus permitting the conquest of terrestrial environments. Among amniotes, genome sequences are available for mammals and birds, but not for non-avian reptiles. Here we report the genome sequence of the North American green anole lizard, Anolis carolinensis. We find that A. carolinensis microchromosomes are highly syntenic with chicken microchromosomes, yet do not exhibit the high GC and low repeat content that are characteristic of avian microchromosomes. Also, A. carolinensis mobile elements are very young and diverse-more so than in any other sequenced amniote genome. The GC content of this lizard genome is also unusual in its homogeneity, unlike the regionally variable GC content found in mammals and birds. We describe and assign sequence to the previously unknown A. carolinensis X chromosome. Comparative gene analysis shows that amniote egg proteins have evolved significantly more rapidly than other proteins. An anole phylogeny resolves basal branches to illuminate the history of their repeated adaptive radiations. 相似文献
78.
The general design and layout of the double-line five-step ship-lock,the water delivery technique for high head ship-lock,the key technical problems of fully lined ship-lock and the monitoring techniques for large-scale miter gates and hoisting equipment under complicated operation conditions of Three Gorges Project (TGP) are introduced.Since the operation of ship-lock in 2003,the operation practice has proved that the design techniques are advanced,rational and reliable.The design and construction of the fully lined ship-lock promotes the development of design theory and practice of ship-lock projects,which makes the construction technology of ship-lock in the world reach a new level. 相似文献
79.
To address the problem that dynamic wind turbine clutter(WTC) significantly degrades the performance of weather radar, a WTC mitigation algorithm using morphological component analysis(MCA) with group sparsity is studied in this paper.The ground clutter is suppressed firstly to reduce the morphological compositions of radar echo. After that, the MCA algorithm is applied and the window used in the short-time Fourier transform(STFT) is optimized to lessen the spectrum leakage of WTC. Finally, the ... 相似文献
80.
Erratum to: New high-strength Ti–Al–V–Mo alloy: from high-throughput composition design to mechanical properties
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Erratum to:International Journal of Minerals, Metallurgy and Materials Volume 26, Number 9, September 2019, Page 1151https://doi.org/10.1007/s12613-019-1854-1The original version of this article unfortunately contained a mistake. The presentation of Fig. 11 was incorrect. The correct version is given below: 相似文献