Male non-coding RNA genes identified by comparative genomic analysis of the Drosophila genomes

This issue published a research article by Yang et al. of Peking University “Significant divergence of sex-re-lated non-coding RNA expression patterns among closely related species in Drosophila”. In a genomic     

限宽水域中船舶平面运动机构试验及水动力导数数值模拟

为探究有限宽度水域中大型船舶的水动力特性,基于计算流体力学(CFD)技术对限宽水域中的平面运动机构(PMM)试验进行数值模拟.在对有限水域宽度的PMM试验的动态模拟上,开发了混合动网格技术,数值计算结果与循环水槽PMM试验结果对比证明采用该方法有效.继而模拟不同宽度水域中的PMM试验,分析船舶水动力随运动速度变化的关系.结果表明,限宽水域中水动力随运动速度变化的非线性特征更为显著,船舶操纵加速度导数增大,位置导数减小,旋转导数的绝对值有所增加,二阶非线性导数值变化较大.     

WGS-84坐标系下改进的广义最小二乘配准算法

针对广义最小二乘算法在WGS-84坐标系中存在收敛速度慢及收敛性能不稳定的问题,提出了一种改进的广义最小二乘算法.该算法以收敛步数作为最小二乘算法中的量测精度加权因子,使得量测精度随着步数的变化而变化,从而实现了收敛步数的减少和收敛之后稳定性的改善,提高了目标跟踪定位的性能.仿真结果表明,改进的广义最小二乘算法优于广义最小二乘算法,进一步验证了该算法的有效性.     

Coexistence of ferromagnetism and metallic conductivity in a molecule-based layered compound

Crystal engineering--the planning and construction of crystalline supramolecular architectures from modular building blocks--permits the rational design of functional molecular materials that exhibit technologically useful behaviour such as conductivity and superconductivity, ferromagnetism and nonlinear optical properties. Because the presence of two cooperative properties in the same crystal lattice might result in new physical phenomena and novel applications, a particularly attractive goal is the design of molecular materials with two properties that are difficult or impossible to combine in a conventional inorganic solid with a continuous lattice. A promising strategy for creating this type of 'bi-functionality' targets hybrid organic/inorganic crystals comprising two functional sub-lattices exhibiting distinct properties. In this way, the organic pi-electron donor bis(ethylenedithio)tetrathiafulvalene (BEDT-TTF) and its derivatives, which form the basis of most known molecular conductors and superconductors, have been combined with molecular magnetic anions, yielding predominantly materials with conventional semiconducting or conducting properties, but also systems that are both superconducting and paramagnetic. But interesting bulk magnetic properties fail to develop, owing to the discrete nature of the inorganic anions. Another strategy for achieving cooperative magnetism involves insertion of functional bulky cations into a polymeric magnetic anion, such as the bimetallic oxalato complex [MnIICrIII(C2O4)3]-, but only insoluble powders have been obtained in most cases. Here we report the synthesis of single crystals formed by infinite sheets of this magnetic coordination polymer interleaved with layers of conducting BEDT-TTF cations, and show that this molecule-based compound displays ferromagnetism and metallic conductivity.     

Molecular evolution of connective tissue growth factor in Cyprinidae (Teleostei: Cypriniformes)

Connective tissue growth factor (CTGF) plays an important role in regulation of cell growth, differentiation, apoptosis and individual development in animals. The study of sequences variation and molecular evolution of CTGF gene across various species of the cyprinid could be helpful for understanding of speciation and gene divergence in this kind of fish. In this study, 19 novel sequences of CTGF gene were obtained from the representative species of the family Cyprinidae using PCR amplification, cloning and sequencing. Phylogenetic relationships of Cyprinidae were reconstructed by neighbor-joining (NJ), maximum parsimony (MP), maximum likelihood (ML) and Bayesian method. Oryzias latipes from the family Cyprinodontidae was assigned to be the outgroup taxon. Leuciscini and Barbini were clustered into the monophyletic lineages respectively with the high nodal supports. The estimation of the ratio of nonsynonymous to synonymous substitution (dN/dS) for the various branches indicated that there stood the different evolution rates between the Leuciscini and the Barbini. With the ratio of dN/dS of the Leuciscini being lower than that of the Barbini, species within the Barbini were demonstrated to be subjected to the relatively less selection pressure and under the relaxable evolution background. A 6 bp indel (insertion/deletion) was found at the 5' end of CTGF gene of Cyprinidae, and this 6 bp deletion only appeared in the Leuciscini, which is a typical characteristic of the Leuciscini and provides evidence for the monophylogeny of the Leuciscini. For the amino acid sequences of CTGF protein, the most variations and Indels were distributed in the signal region and IGFBP region of this protein, implying that these variations were correlated with the regulation of the CTGF gene expression and protein activity.     

Serial time-encoded amplified microscopy for ultrafast imaging based on multi-wavelength laser

In this paper, a serial time-encoded amplified microscopy （STEAM） by employing a multiwavelength laser as the light source is proposed and experimentally demonstrated. This system achieves ultrafast optical imaging with a tunable frame rate. The measuring range depends on the spectrum width of the multiwavelength laser. Through tuning the speed of the modulating signal, the frame rate ranges from 100 to 250 MHz. In addition, the spatial resolution can be improved by increasing the group velocity dispersion and reducing the wavelength spacing. Finally, with the development of photonic integrate circuits （PIC）, the multiwavelength laser source has the potential for integration on a photonic chip and thus the size of the proposed STEAM could be reduced in the future.     

不同注聚时机聚合物驱含水率变化规律研究

因海上平台寿命有限,研究聚合物驱不同注聚时机的生产特征及产能预测,对在有效时间内实现经济高效生产很有必要。通过一维物理模拟实验和数值模拟方法,研究了不同注聚时机聚合物驱含水率变化规律。研究结果显示,早期注聚可以提高油藏最终采收率,但含水变化率随注聚时机的延后而增大。综合分析认为,通过动态数据的含水变化率总结,建立累计产油量和含水变化率的关系式,可以实现对注聚受效井生产能力的预测。     

模糊随机需求条件下三级供应链的数量折扣协调策略

为了分析模糊随机需求条件下三级供应链协调策略,考虑提前期内需求为模糊随机变量, 建立由供应商、制造商和零售商所组成的三级供应链优化决策和数量折扣协调模型, 其中订单量、再订货点为决策变量.首先推导出提前期内需求为模糊随机变量条件下的各成员成本和供应链总成本函数,然后设计相应的算法对模型进行求解,最后通过算例验证了模型的实用性, 并进行比较分析.结果表明：采用数量折扣协调策略能够降低三级供应链总成本;如果在制造商的上下游企业同时引入数量折扣策略,此时所引起的三级供应链总成本低于仅在制造商的下游企业引入数量折扣时的三级供应链总成本,亦低于未提供任何数量折扣策略时的三级供应链总成本;模糊随机需求条件下三级供应链总成本高于随机需求条件下的三级供应链总成本.     

一种混合退化系统剩余寿命预测方法

针对传统的预测方法不能同时考虑线性和非线性退化问题,提出了一种基于维纳过程的带随机参数和确定参数的混合退化模型.基于首达时间(FHT)的概念给出了剩余寿命(RUL)的解析渐进显式形式,模型中随机参数通过Kalman滤波技术实时更新,确定参数采用极大似然估计进行估计.最后,采用陀螺仪实验数据验证了该方法的有效性.