Molecular structure and biological function of proliferating cell nuclear antigen

Proliferating cell nuclear antigen (PCNA) is the core component of replication complex in eukaryote. As a processive factor of DNA polymerase delta, PCNA coordinates the replication process by interacting with various replication proteins. PCNA appears to play an essential role in many cell events, such as DNA damage repair, cell cycle regulation, and apoptosis, through the coordination or organization of different partners. PCNA is an essential factor in cell proliferation, and has clinical significance in tumor research. In this article we review the functional structure of PCNA, which acts as a function switch in different cell events.     

通气状况与氮素形态对水稻和旱稻生长的影响

采用营养液培养法研究通气状况与氮素形态对水、旱稻生长和养分吸收的影响。结果表明，通气与不通气相比，通气明显的增加了植物地上部和地下部的生物量；同时验证了水稻喜NH4^ 和旱稻喜NO3^-的吸收特性。叶面积测定与地上部生物量的趋势完全一致，表明这种生物量的增加与光合作用增强、光合面积增大有关。植物地上部全N、P、K含量测定显示，通气状况与氮素形态对水、旱稻生物量的影响与N、P、K营养元素的吸收没有直接关系。     

用于海水淡化堆的闪蒸器蒸汽发生系统

核电站蒸汽发生器出现故障的几率较高。为减少蒸汽发生的质量和体积 ,提出用降压闪蒸的方法来产生蒸汽以替代蒸汽发生器。结合 10 MW核供热堆海水淡化系统 ,分析了闪蒸器蒸汽发生系统的特点。改进设计后 ,闪蒸器的体积比蒸发器小 4 0 % ,质量小约 80 % ;使用闪蒸器旁路调节对改善运行特性起很大作用。该设计拟用于摩洛哥核能海水淡化示范系统中。     

胰岛素原转化酶基因克隆及序列测定

目的研究胰岛素抵抗和胰岛素缺乏与Ⅱ型糖尿病发病机制的关系.方法Ⅱ型糖尿病普遍存在胰岛素、胰岛素原障碍,胰岛β细胞分泌出胰岛素原经胰岛素原转化酶(Prohormone convertase,PC2)去除部分肽段后形成胰岛素.结果与结论若PC降解功能异常可导致胰岛素原及其代谢产物不适当分泌引起胰岛素缺乏,研究该基因分布和表达的变化,对探讨糖尿病胰岛素抵抗的发病机制奠定基础.     

餐厨垃圾干式厌氧消化的试验研究

采用猪粪厌氧消化的消化污泥为接种物,在中温(37℃)条件下,以连续进料的方式对餐厨垃圾的干式厌氧消化进行了运行试验研究,监测整个试验过程中产气量、pH、VFA、碱度、酸碱比等能够反应厌氧消化系统指标。结果表明,实验中系统最佳有机负荷为2.3 kg/(m~3·d)(以VS计)。正常运行过程中pH稳定在8.2～8.5之间,VFA稳定在7 300～12 000 mg/L,碱度在17 000～19 000 mg/L范围内,氨氮在3 500～5 500 mg/L范围内,底物含水率b保持上升并且达到93%左右。     

多目标有约束关系模糊网络图决策模型及其应用

根据多目标模糊决策理论，本文首先提出接近度概念，其次计算模糊关系矩阵并将其转化为接近度网络图。在此基础上，建立了基于网络最大流寻优的多目标有约束关系的模糊网络图决策模型。最后，应用该模型对某矿井工业广场的工程设计位置问题进行了多目标决策，效果很好。     

A New ID-Based Proxy Multi-Signature Scheme from Bilinear Pairings

ID-based public key cryptosystem can be a good alternative for certifieate-based public key setting. This paper provides an efficient ID-based proxy multi signature scheme from pairings. In the random oracle model, we prove that our new scheme is secure against existential delegation forgery with the assumption that Hess＇s scheme-1 is existential unforgeable, and that our new scheme is secure against existential proxy multi-signature forgery under the hardness assumption of the computational Diffie-Hellman problem.     

稀土-过渡族—Y-Hf、Y-Zr二元相图的计算

本文采用L.Kaufman的计算方法,用规则溶体模型对稀土元素钇(Y)与难溶过渡族元素锆(Zr)、铪(Hf)的二元系:钇—锆,钇—铪进行了相平衡计算。并比较了此二系的计算相图和实测相图,二者符合良好。     

Improving the solidification structure of commercially pure aluminium with electropulse acting on liquid metal

The effect of electropulse on the solidification structure of commercially pure aluminium was studied. The orthogonal array L9 was used to determine the effect of three process parameters of electropulse modification (EPM), which were pulse current intensity, pulse frequency, and treating time. For each factor, three levels were chosen to cover the experimental region. According to the experimental results, the solidification structure of commercially pure aluminium was modified from large grains with columnar crystals to finer grains with equiaxed crystals, by allowing the electropulse to act on liquid aluminium. However, the solidification structures could be refined differently at different EPM parameters. Certain EPM parameters should be selected to get the optimum solidification structure. Among the three parameters, pulse frequency was the most important factor influencing the solidification structure, the secondary factor was current intensity, and treating time was the third one. The optimum parameters were the pulse frequency of 5 Hz, the current intensity of 68 A, and the treating time of 10 s.     

高层建筑结构选型影响因素分析

现今,越来越多的高层建筑建筑伫立于城市之中,要想在建筑行业得到利益与名义的双丰收,光靠地皮的价位是远远不够的,更重要的是建筑结构选型的标新立异、材料施工的安全保障和后期服务的全面到位。下面,就高层建筑结构选型这一问题进行具体探究。