脑让人每日耳目一新

脑的"可塑性"是现代科学的伟大发现之一,但神经科学家大卫?伊戈曼(David Eagleman)认为这种描述具有一定误导性."塑料"通过模具固定为一种特定的形状,而脑的物质结构却处在不断变化之中.但伊戈曼无法摆脱这个词:"所有的文献都在用这个词,我只能尽量避免."伊戈曼对脑的"计算机类比"也有所质疑.他创造出了"活体连...     

GPS单频PPP电离层延迟改正模型探讨

针对电离层延迟会导致GPS单频精密单点定位精度严重缺失的情况,分别探讨了克罗布歇模型、格网模型和历元差分模型,并采用IGS跟踪站数据进行电离层延迟改正。同时根据改正后的单频精密单点定位精度,比较了这三种电离层延迟改正模型的改正效果。结果表明:历元差分模型的改正效果最好,其改正后单频精密单点定位精度可达到厘米级,能较好地符合实际应用要求。     

Sperm viability in the reproductive tract of females in a population of Sceloporus mucronatus exhibiting asynchronous reproduction

Asynchronous reproduction is a common phenomenon in high-elevation populations of lizards from Central México. Sperm storage in the reproductive tract of females is the mechanism for making oocyte fertilization possible. Our study addresses questions related to functional oviductal sperm storage of females mating on different dates throughout the reproductive season. A population of Sceloporus mucronatus with copulation in the summer and ovulation in the fall was chosen for this experiment. Eleven females that copulated in the field during June and 13 females that copulated in captivity during August were maintained in the laboratory until parturition. The number of pregnant females and the litter sizes produced in each experimental group were indicative of the viability of the stored sperm. Sperm stored in the reproductive tract of females were able to fertilize eggs after 4 months. No significant differences were found in the number of pregnant females between the 2 experimental groups nor in the litter sizes that they produced. We found that the amount of time sperm were held in the female reproductive tract (ca. 3 months) had no effect on the capacity of sperm to fertilize eggs. Histological examination of 8 oviducts collected before the mating season eliminated the possibility of sperm storage from one year to the next. In this system, sperm retention could have evolved as a response mechanism to deal with the asynchrony between sexes in the reproductive cycles. However, we cannot rule out alternative hypotheses.     

乾陵地理信息数据库的建设与开发

文章的目的是提供一个综合的信息管理和空间数据分析工具,为文物保护部门对乾陵历史遗址的文物保护现状进行分析评估提供决策依据。文章采用当前国内外流行的大型数据库技术和处理空间地理信息的GIS技术,开发了乾陵地理信息数据库并在ArcGIS平台上与空间地理矢量图相连接,构成一个数字化乾陵保护区空间地理信息系统。结果表明:该系统的建立和运行,不仅能对乾陵保护区各种文物资源的现状进行评估,还能对文物保护区的保护规划提供决策服务。     

Simulating FAS-induced apoptosis by using P systems

In contrast to differential equations, P systems are an unconventional model of computation which takes into consideration the discrete character of the quantity of components and the inherent randomness that exists in biological phenomena. The key feature of P systems is their compartmentalised structure which represents the heterogeneity of the structural organisation of the cells, and where one can take into account the role played by membranes in the functioning of the system, for example signalling at the cell surface, selective uptake of substances from the media, diffusion across different compartments, etc. We show here that P systems can be a reliable tool for Systems Biology and could even outperform in some cases the current simulation techniques based on differential equations. We will also use a strategy based on the well known Gillespie algorithm but running on more than one compartment called Multi-compartmental Gillespie Algorithm.     

Genetic background of phenotypic variation

A noteworthy feature of the living world is its bewildering variability. A key issue in several biological disciplines is the achievement of an understanding of the hereditary basis of this variability. Two opposing, but not necessarily irreconcilable conceptions attempt to explain the underlying mechanism. The gene function paradigm postulates that phenotypic variance is generated by the polymorphism in the coding sequences of genes. However, comparisons of a great number of homologous gene and protein sequences have revealed that they predominantly remained functionally conserved even across distantly related phylogenic taxa. Alternatively, the gene regulation paradigm assumes that differences in the cis-regulatory region of genes do account for phenotype variation within species. An extension of this latter concept is that phenotypic variability is generated by the polymorphism in the overall gene expression profiles of gene networks. In other words, the activity of a particular gene is a system property determined both by the cis-regulatory sequences of the given genes and by the other genes of a gene network, whose expressions vary among individuals, too. Novel proponents of gene function paradigm claim that functional genetic variance within the coding sequences of regulatory genes is critical for the generation of morphological polymorphism. Note, however, that these developmental genes play direct regulatory roles in the control of gene expression.     

┱?例杨金彪;福建省南平市第

鸨?114尼美舒利致肝功能损伤1例陈瑶;李岚;厦门市妇幼保健院药剂科,上海儿童医学中心药剂科 厦门361000,上海200000尼美舒利;;肝功能损害0海峡药学Strait Pharmaceutical Journal118-119R725.9E06938E;E069_38陈瑶;114-115门诊药房实行专科药师制度的必要性陈成辉;何丽芳;     

Self-Dual Hadamard Bent Sequences

A new notion of bent sequence related to Hadamard matrices was introduced recently,motivated by a security application(Solé, et al., 2021). The authors study the self-dual class in length at most 196. The authors use three competing methods of generation: Exhaustion, Linear Algebra and Gr?bner bases. Regular Hadamard matrices and Bush-type Hadamard matrices provide many examples. The authors conjecture that if v is an even perfect square, a self-dual bent sequence of length v always exists. The ...     

基于自动变速的混合动力装载机控制策略

为了提高装载机能源的利用率与变矩传动效率,通过分析某5 t装载机的工况特点,提出了基于自动变速的并联式混合动力方案;采用模糊逻辑控制策略,通过在线估计系统需求转矩与车速,以需求转矩、超级电容SOC值、车速、油门开度及液力变矩器效率作为输入,输出发动机与电动机的工作点及系统挡位.结果表明:发动机效率提高,超级电容SOC值稳定,挡位变化合理有效,混合动力比传统装载机节油约9.56%,混合动力自动变速比传统装载机节油约11.82%,改善了燃油经济性.     

RSS拓补结构机座的动态优化

以燃气轮机透平端RSS(旋转对称支承板)机座为研究背景,通过用D’Alembert原理建立了RSS机座的拓补优化域和等价边界条件,从而实现了用均匀化方法的RSS机座拓扑结构优化,得到了旋转对称的弧形支承板拓扑结构的机座.然后,结合原来RSS机座的机构特征在ANSYS workbench中建立了RSS拓补结构光滑有限元模型,并进行了工作条件下的模态分析,以前三阶模态振型中轴承座的振型作为当量静载荷加载到原模型对比计算,验证边界条件的正确性.以RSS机座弧形支承板的四个关键尺寸为设计变量,以机座的变形量和应力为目标函数,进行了随频率变化的动态优化设计.通过优化改变了RSS拓补结构的动态特性,使固有频率远离了工作频率.