Genetic background of phenotypic variation

A noteworthy feature of the living world is its bewildering variability. A key issue in several biological disciplines is the achievement of an understanding of the hereditary basis of this variability. Two opposing, but not necessarily irreconcilable conceptions attempt to explain the underlying mechanism. The gene function paradigm postulates that phenotypic variance is generated by the polymorphism in the coding sequences of genes. However, comparisons of a great number of homologous gene and protein sequences have revealed that they predominantly remained functionally conserved even across distantly related phylogenic taxa. Alternatively, the gene regulation paradigm assumes that differences in the cis-regulatory region of genes do account for phenotype variation within species. An extension of this latter concept is that phenotypic variability is generated by the polymorphism in the overall gene expression profiles of gene networks. In other words, the activity of a particular gene is a system property determined both by the cis-regulatory sequences of the given genes and by the other genes of a gene network, whose expressions vary among individuals, too. Novel proponents of gene function paradigm claim that functional genetic variance within the coding sequences of regulatory genes is critical for the generation of morphological polymorphism. Note, however, that these developmental genes play direct regulatory roles in the control of gene expression.     

论气化炉超负荷运行的危害

我公司气化车间是以三台德士古水煤浆加压气化炉为主要设备的生产车间.车是自2006年投产试运行以来,历经坎坷,几经磨练,现在终于步入正轨,进入高产、稳定、长周期运行的可喜局面.这里,我要说一说我们曾今走过的弯路,虽然不够深刻,但也是我精心总结,以供大家参考,希望有所帮助.     

高校体育专业女生足球普修课教学探讨

对于高校体育专业学生而言,无论是男生还是女生,必须进行足球普修。普修的基本任务是通过学习,使学生掌握足球的基本理论知识和基本技术,了解足球运动的基本规律,基本胜任中学的足球教学和训练。基于女生的基础和兴趣如何使她们完成普修课的教学任务是我们目前迫切需要解决的问题。     

物理教学与美育的渗透研究

爱美之心,人皆有之,在物理学科教学中渗透美育,有利于激发学生学习兴趣,提高教学质量和全面培养学生素质。本文探索了在中学物理教学中融合美育的问题,为中学生的全面素质教育提供了一个侧面的参考。     

浅析高职院校化学实验教学对学生能力的培养

本文首先对高职院校化学实验室的作用和教学工作的改革创新及学生实践能力的培养做了全面的分析和思考。然后就改革化学实验教学培养创新实践人才提出了自己的看法。     

具有吸收项和局部源的一维p-拉普拉斯方程解的熄灭

利用Lp模估计和Sobolev嵌入不等式,研究了一维情形下p-拉普拉斯方程解的熄灭,并给出解在有限时刻熄灭的充分条件及衰退估计.     

┱?例杨金彪;福建省南平市第

鸨?114尼美舒利致肝功能损伤1例陈瑶;李岚;厦门市妇幼保健院药剂科,上海儿童医学中心药剂科 厦门361000,上海200000尼美舒利;;肝功能损害0海峡药学Strait Pharmaceutical Journal118-119R725.9E06938E;E069_38陈瑶;114-115门诊药房实行专科药师制度的必要性陈成辉;何丽芳;     

Self-Dual Hadamard Bent Sequences

A new notion of bent sequence related to Hadamard matrices was introduced recently,motivated by a security application(Solé, et al., 2021). The authors study the self-dual class in length at most 196. The authors use three competing methods of generation: Exhaustion, Linear Algebra and Gr?bner bases. Regular Hadamard matrices and Bush-type Hadamard matrices provide many examples. The authors conjecture that if v is an even perfect square, a self-dual bent sequence of length v always exists. The ...     

显德汪矿合理支柱迎山角研究与实践

结合显德汪煤矿实际情况，通过对支柱迎山角在倾斜工作面支护作用机理的分析，阐明了合理支柱迎山角重要性及如何确定支柱迎山角，并结合工程实际提出了简便可行的支柱迎山角施工与验收方法。     

常见家畜毛的扫描电镜检验

本文用扫描电镜对马、牦牛、驴、羊等家畜背部的毛进行了初步观察研究，结果表明动物毛干的毛小皮呈覆瓦样排列，不同动物毛干的毛小皮形态和排列各有特征。各动物毛干内部结构均由毛小皮层、毛皮质和毛髓质构成，毛皮质呈无结构的均质状，毛髓质的形态各异，且不同动物毛干的毛皮质和毛髓质所占比例不同。毛小皮的形态学差异以及毛干内部皮质和髓质所占的比例可以作为种属认定的依据。