实时实现MPEG2运动估计的DSP处理系统

本文根据ＭＰＥＧ２的图像标准与要求，利用若干大规模集成电路芯片，设计了实时实现活动图像运动估计的ＤＳＰ处理系统板，通过序列图像的测试，证明其工作正常，性能可靠，完全符合ＭＰＥＧ２的技术规范，从而为我国近期实现ＭＰＥＧ２的编解码系统、乃至ＨＤＴＶ实验系统在硬件方面打下了良好的基础。     

Nuclear localization and signalling activity of phosphoinositidase C beta in Swiss 3T3 cells.

The hydrolysis of phosphatidylinositol 4,5-bisphosphate (PtdInsP2) is a widespread receptor-coupled signalling system at the plasma membrane of most eukaryotic cells. The existence of an entirely separate nuclear phosphoinositide signalling system is suggested from evidence that purified nuclei synthesize PtdInsP2 and phosphatidylinositol 4-phosphate (PtdInsP) in vitro and that a transient decrease in the mass of these lipids occurs when Swiss 3T3 cells are cultured in the presence of insulin-like growth factor-1 (IGF-1). These IGF-1-dependent changes in inositol lipids coincide with an increase in nuclear diacyglycerol and precede translocation to the nucleus and activation of protein kinase C (refs 5, 6). Circumstantial evidence that links these changes with mitosis comes from the isolation of a 3T3 clone that expresses the type-1 IGF receptor and binds IGF-1 peptide but does not respond mitogenically or show transient mass changes in nuclear inositol lipids. A key question is how IGF-1 initiates the rapid breakdown of PtdInsP and PtdInsP2 in the nucleus. Here we present evidence that nuclei of 3T3 cells contain the beta-isozyme of phosphoinositidase C, whereas the gamma-isozyme is confined to the cytoplasm and that IGF-1 treatment stimulates exclusively the activity of nuclear phosphoinositidase C.     

磁光光盘动态性能的研究

该文报道了所研制的具有AIN/TbFeCo/AIN/AI四层结构磁光光盘的动态性能测试结果.当记录信息位尺寸为1μm时,信息读出载噪比大于45dB,载噪比随盘片径向位置而异.文中根据测试结果,讨论了影响载噪比的诸因素.     

数据采集与光条图象细化新方法——用于三维计算机视觉系统

介绍了具有位置反馈信息旋转平台的图象数据采集方法,以及对采集到的图象进行智能化快速细化的新方法,使得在一周内的36幅图象做到边采集边细化,而且仅用40s时间。     

Prediction of the structure of a receptor-protein complex using a binary docking method.

To validate procedures of rational drug design, it is important to develop computational methods that predict binding sites between a protein and a ligand molecule. Many small molecules have been tested using such programs, but examination of protein-protein and peptide-protein interactions has been sparse. We were able to test such applications once the structures of both the maltose-binding protein (MBP) and the ligand-binding domain of the aspartate receptor, which binds MBP, became available. Here we predict the binding site of MBP to its receptor using a 'binary docking' technique in which two MBP octapeptide sequences containing mutations that eliminate maltose chemotaxis are independently docked to the receptor. The peptides in the docked solutions superimpose on their original positions in the structure of MBP and allow the formation of an MBP-receptor complex. The consistency of the computational and biological results supports this approach for predicting protein-protein and peptide-protein interactions.     

奥氏体-贝氏体复相组织形态的研究

在60Si2MnA钢等温淬火工艺和性能研究的基础上,用MEF-3型金相显微镜和JEM-200CX型透射电子显微镜对等温转变产物的组织形态进行了观察研究。并用Rigku D/maxⅢB型X-射线衍射仪测定了样品的残余奥氏体体积分数。实验结果表明,奥氏体-贝氏体复相组织强韧性好的原因在于含有一定数量的残余奥氏体和变态贝氏体组织,且贝氏作为无碳化物贝氏体。     

Short alanine-based peptides may form 3(10)-helices and not alpha-helices in aqueous solution.

Short alanine peptides, containing 16 or 17 residues, appear to form alpha-helices in aqueous solution. But the main spectroscopic analyses used on helical peptides (circular dichroism and nuclear magnetic resonance) cannot distinguish between an alpha-helix (in which the ith residue is hydrogen-bonded to residue i + 4; ref. 9) and the next most common peptide helix, the 3(10)-helix10 (i-->i + 3 hydrogen-bonding). To address this problem we have designed single and doubly spin-labelled analogues of alanine-based peptides in which the nitroxide spin label forms an unbranched side chain extending from the sulphur atom of a cysteine residue. Here we report the circular dichroism, Fourier-transform infrared and electron-spin resonance spectra of these peptides under helix-forming conditions. The infrared absorbance gives an amide I' band with a frequency that is substantially different from that observed for alpha-helices. The electron-spin resonance spectra of doubly labelled helices show that the ranking of distances between side chains, around a single turn (residues 4-8), is inconsistent with an alpha-helical structure. Our experiments suggest that the more likely peptide geometry is a 3(10)-helix.     

2,5-二甲氧基-4-吗啉基苯基重氮氯化锡复盐的合成

本文采用较为简便的合成手段,较好地合成了一种高速感光重氮型化合物--2,5-二甲氧基-4-码啉基苯基重氮氯化锡复盐,并经 IR 谱、′HNMR 谱,以及元素分析等检测,证实该产物的存在.产品紫外特征吸收峰艾λ_(max)=398. 2nm,热分解温度为158℃.     

韭菜凝集素的纯化及部分性质的研究

用葡聚糖凝胶柱层析法从韭菜的叶片组织分离出一种对新鲜兔红细胞有强烈凝集作用的凝集素，ＰＡＧＥ鉴定和高碘酸－Ｓｃｈｉｆｆ试剂反应均显单一条带。ＳＤＳ－ＰＡＧＥ分析表明该凝集素含有３个亚基，其相对分子质量分别约为３１０００、２４０００和２１０００。韭菜凝集素具有一定的热稳定性，在酸、碱处理中该凝集素对碱处理较酸处理稳定，氨基酸组成分析表明韭菜凝集素含有１４种氨基酸，其中半胱氨酸含量较高。     

狄拉克（Dirac）与当代物理学

从量子力学、真空、大数假说、磁单极子诸方面，阐述了坎拉克的治学思想和研究方法的特点及其对当代物理学所做出的重大贡献．